Ntp Gmm
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Ntp Gmm
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Author :
language : en
Publisher:
Release Date : 2005
Ntp Gmm written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Carcinogenicity testing categories.
Genetically Modified Model Report On Toxicology And Carcinogenesis Study Of Glycidol Cas No 556 52 5 In Genetically Modified Haploinsufficient P16ink4a P19arf Mice Gavage Study
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Author : J. K. Dunnick
language : en
Publisher: DIANE Publishing
Release Date : 2008-06
Genetically Modified Model Report On Toxicology And Carcinogenesis Study Of Glycidol Cas No 556 52 5 In Genetically Modified Haploinsufficient P16ink4a P19arf Mice Gavage Study written by J. K. Dunnick and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06 with categories.
Glycidol is used as a chemical intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, Glycidol ethers, and amines. Glycidol was nominated for carcinogenecity study by the Environmental Protection Agency (EPA). Glycidol was selected for study in the haploinsufficient p16Ink4a/p19Arf mouse because it was found to be carcinogenic in rats and mice in conventional 2-year rodent studies (NTP, 1990), but was negative in a study in p53+/- mice (Tennant et al., 1999). In this study, male and female mice received Glycidol (greater than 95% pure) by gavage for 40 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 2006-08
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08 with Environmental health categories.
Alternative Sweeteners
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Author : Lyn O'Brien-Nabors
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Alternative Sweeteners written by Lyn O'Brien-Nabors and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Technology & Engineering categories.
The fourth edition of Alternative Sweeteners follows the same formula as the previous three books by discussing each sweetener in terms of its characteristics. Qualities covered include means of production, physical characteristics, utility, and relative sweetness (compared to sucrose). Technical qualities covered include admixture potential, application, availability, shelf life, transport, metabolism, carcinogenicity, and other toxicity evaluation data. A new chapter on the sweetener Advantame has been added, and new contributors have updated information throughout the book. Also new is a section on how stevia sweeteners have been examined and deemed safe by the Joint FAO/WHO Expert Committee on Food Additives and the US FDA.
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 3 Environmental Toxicologic Pathology And Major Toxicant Classes
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Author : Wanda M. Haschek
language : en
Publisher: Elsevier
Release Date : 2023-02-24
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 3 Environmental Toxicologic Pathology And Major Toxicant Classes written by Wanda M. Haschek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-24 with Medical categories.
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides updated and revised chapters for in-depth discussions of toxicologic pathology for the protection of the environment and food supplies - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Neet Guide For Physics Chemistry Biology
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Author : Disha Experts
language : en
Publisher: Disha Publications
Release Date : 2017-08-29
Neet Guide For Physics Chemistry Biology written by Disha Experts and has been published by Disha Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-29 with Study Aids categories.
The book NEET Guide for Physics, Chemistry & Biology has been written exclusively to help students crack the NEET exam. The book covers the 100% syllabus in Physics, Chemistry and Biology. The book follows the exact pattern of the NCERT books. Thus Physics has 29, Chemistry has 30 and Biology has 38 chapters. Each chapter contains Key Concepts, Solved Examples, Exercise with detailed solutions. The exercise contains MCQs as per the pattern of the NEET exam. This is followed by an exhaustive exercise. A real cracker, this book is complete in all aspects and is a must for every NEET aspirant. The book is also useful for AIIMS/ JIPMER/ AMU/ KCET etc.
The Stevia Deception
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Author : Bruce Fife
language : en
Publisher: Piccadilly Books, Ltd.
Release Date : 2017-08-14
The Stevia Deception written by Bruce Fife and has been published by Piccadilly Books, Ltd. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-14 with Health & Fitness categories.
Through the power of persuasive advertising and clever marketing, we’ve been sold on the idea that stevia is a natural herbal sweetener that is not only harmless but even health-promoting. As such, it is promoted as a better choice over sugar or other low-calorie sweeteners. Stevia has rapidly become a multimillion-dollar industry. Despite all of the marketing hype, stevia is not the innocent little herb it is made out to be—and it is not harmless. The stevia sweetener you purchase at the store is a highly refined, purified chemical that is little different from any other artificial sweetener, with many of the same drawbacks and dangers. The author’s observation of troubling adverse reactions associated with stevia led him on an investigation that uncovered disturbing facts hidden from the public, including studies that contradict the sweetener’s safety and assumed benefits. In this book, you will learn why you should never use stevia if you want to lose excess weight or control diabetes. You will also learn why all low-calorie sweeteners are potentially dangerous, and what options you have available. The information in this book comes directly from published studies, historical facts, and the author’s personal experiences. In this book you will learn that stevia is not an herb but a highly refined chemical acts like an artificial sweetener is addictive can cause digestive distress alters the gut microbiome is a gut excitotoxin promotes obesity, diabetes, and metabolic syndrome can cause allergic reactions
Computational Systems Pharmacology And Toxicology
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Author : Rudy J Richardson
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-03-01
Computational Systems Pharmacology And Toxicology written by Rudy J Richardson and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-01 with Science categories.
The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics. This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.
Advances In Ecology Environment And Conservation Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Advances In Ecology Environment And Conservation Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.
Advances in Ecology Environment and Conservation Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ecology Environment and Conservation. The editors have built Advances in Ecology Environment and Conservation Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ecology Environment and Conservation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Ecology Environment and Conservation Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Animal Models In Toxicology
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Author : Shayne C. Gad
language : en
Publisher: CRC Press
Release Date : 2016-04-05
Animal Models In Toxicology written by Shayne C. Gad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-05 with Medical categories.
Animal Models in Toxicology is a single-source reference for the use of animal models in toxicology. Chapters cover nine species used in toxicology and experimental biology. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provides an excellent introductory "course" alon