Nuclear Matrix
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Molecular Biology Of Steroid And Nuclear Hormone Receptors
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Author : Leonard Freedman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Biology Of Steroid And Nuclear Hormone Receptors written by Leonard Freedman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Against this deep historical backdrop of the founding studies of intercellular signaling, molecular biology sprang into existence a mere forty years ago, rooted in the revelation of regulable gene expression in bacteria. But contemporaneous with those classical analyses of transcriptional regulation of the lactose operon, the mod em era of signal transduction was inaugurated by the identification of cAMP as a second messenger -- an intracellular mediator of hormonal activation of glycogen catabolism (Sutherland and RaIl 1960). Later in that same decade, it emerged that cAMP is a critical signal not only in metazoans, but even in bacteria, where it serves an analogous function as a critical switch that activates expression of genes re quired for catabolism of complex carbon sources, including those of the lactose operon.
Nuclear Import And Export In Plants And Animals
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Author : Tzvi Tzfira
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-25
Nuclear Import And Export In Plants And Animals written by Tzvi Tzfira and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-25 with Science categories.
Nuclear Import and Export in Plants and Animals provides insight into the remarkable mechanisms of nuclear import and export. This book covers a range of topics from the nuclear pore structure, to nuclear import and export of macromolecules in plant and animal cells. In addition, the book covers the special cases of nuclear import of Agrobacterium T-DNA during plant genetic transformation, nuclear import and export of animal viruses, and nuclear intake of foreign DNA. A chapter on research methods to study nuclear transport concludes the book.
Genome Structure And Function
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Author : C. Nicolini
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genome Structure And Function written by C. Nicolini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Proceedings of the NATO Advanced Study Institute on Genome Structure and Function, held in Marciana Marina, Elba, Italy, 13-23 June 1996
Molecular Basis Of Human Cancer
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Author : C. Nicolini
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Molecular Basis Of Human Cancer written by C. Nicolini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.
During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the course was to address, in a tutorial and structural fashion, the molecular basis of human cancer, including the mechanism of signal transduction in mammalian cells, the genetic mechanism of malignant transformation in man, growth factors, hormone receptors, cell membrane and cytoskeleton, and DNA high order structure. The course had this as its major objective and the resulting book reflects it. The participants were exposed to a critical evaluation of current knowledge about cancer and to some of the key problems that remain as stumbling blocks to our eventual understanding of this important biological and medical problem. Through the media of formal and informal lectures, workshops, symposia and informal discussions, a select group of interested young and senior scientists were acquainted with many of the aspects of human cancer.
Molecular And Cellular Approaches To The Control Of Proliferation And Differentiation
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Author : Gary Stein
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Molecular And Cellular Approaches To The Control Of Proliferation And Differentiation written by Gary Stein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Molecular and Cellular Approaches to the Control of Proliferation and Differentiation focuses on molecular and cellular approaches used to control cell proliferation and differentiation. This book discusses the basic mechanisms involved in the regulation of cell growth, emphasizing the coupling of proliferation and the progressive expression of several specific cellular phenotypes. This text is organized into three sections encompassing 12 chapters and begins with an introduction to cell proliferation and how it is regulated by growth factors and nuclear protooncogenes in cell proliferation. The book then discusses mitosis and its investigation by means of the cell biological, genetic, biochemical, and immunological approaches, along with the model for mitotic regulation. The next chapters examine the manner in which cell structure is involved in the selective expression of genes associated with proliferation and differentiation and, how gene expression in response modulates both intracellular (nuclear matrix and cytoskeleton) and extracellular (extracellular matrix) architecture. The extent to which common signaling mechanisms and regulatory events are operative in the control of proliferation and differentiation is also addressed. The book concludes by analyzing the involvement of histone modifications in the condensation of mitotic chromosomes. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in genetics, cell biology, biological chemistry, microbiology, and immunology.
Biochemical And Structural Dynamics Of The Cell Nucleus
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Author : Eugenia Wang
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Biochemical And Structural Dynamics Of The Cell Nucleus written by Eugenia Wang and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Biochemical and Structural Dynamics of the Cell Nucleus is a collection of papers dealing with the biology of the cell nucleus. The collection describes the methods used in isolating and defining the chemistry and functional interactions of the nuclear components. Some papers also discuss the diversity of the roles that these components play in regulating cellular phenotypes, differentiation, and proliferation. One paper discusses the possible role for lamin A in muscle differentiations, where due to its presence and the appearance of A-type lamins during the differentiation of a number of cell types, lamin A or any of its isoelectric variants cannot specifically be responsible for the induction of muscle specific gene expression. The work of Loewinger and McKeon (1988) can show evidence of the role for lamin A in the differential expression of muscle-specific genes during the process of myogenesis if the investigator uses an alternative method. Several papers also discuss the dynamics of assembly and disassembly of the nuclear lamina and envelope, DNA- and RNA-binding proteins, as well as the nucleocytoplasmic transport. The collection can prove valuable to biochemists, cellular biologists, microbiologists, and molecular biologists.
Recent Advances In Steroid Hormone Action
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Author : V. K. Moudgil
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-07-22
Recent Advances In Steroid Hormone Action written by V. K. Moudgil and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-22 with Science categories.
No detailed description available for "Recent Advances in Steroid Hormone Action".
International Review Of Cytology
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Author :
language : en
Publisher: Academic Press
Release Date : 1996-01-04
International Review Of Cytology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-04 with Science categories.
International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Molecular Cytology V1
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Author : Jean Brachet
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Molecular Cytology V1 written by Jean Brachet and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Molecular Cytology presents an integrated version about the morphology and biochemistry of the cell. This two-volume book focuses on the dynamic aspects of cytology and on the nucleocytoplasmic interactions in unicellular organisms and eggs. The first chapter covers the history of cell, cytology, and nucleic acids, as well as the uniformity and diversity in cell. The book then discusses various methods used in cell biology, including optical, cytochemical, biological, biochemical, and biophysical techniques. It also examines the activities of cytoplasm and nucleus during interphase. The final chapter describes various phases of the cell cycle, the structure of metaphase chromosomes, the molecular organization of the mitotic apparatus, and the cytokinesis, with emphasis on the main mitotic abnormalities. With the aim of linking the morphology and biochemistry of the cell, this book is intended for advanced students, research workers, biochemists, and cytologists who wish to broaden their knowledge in cell.
The Eukaryotic Nucleus
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Author : Samuel H. Wilson
language : en
Publisher: CRC Press
Release Date : 1990-08-09
The Eukaryotic Nucleus written by Samuel H. Wilson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-09 with Science categories.
This series provides, in two volumes, a complete and exhaustive review of the subject of the eukaryotic nucleus, the site of the DNA. The focus of the book is how the information in the DNA is transcribed, accessed and maintained.