Nucleic Acid Therapeutics In Cancer
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Nucleic Acid Therapeutics In Cancer
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Author : Alan M. Gewirtz
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-03-25
Nucleic Acid Therapeutics In Cancer written by Alan M. Gewirtz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-25 with Medical categories.
A cutting-edge review of the important issues underlying the therapeutic use of nucleic acid-mediated gene silencing. Topics range from basic methodology and delivery to targeting and clinical targets. The authors thoroughly explain the latest developments in RNA biology, as well as the underpinnings of RNA interference, oligodeoxynucleotide delivery into cells, and strategies for targeting these molecules to accessible regions within the mRNA. They also provide some examples of how these new therapeutic compounds are being used clinically.
Nucleic Acid Therapeutics In Cancer
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Author : Alan M Gewirtz
language : en
Publisher:
Release Date : 2004-03-25
Nucleic Acid Therapeutics In Cancer written by Alan M Gewirtz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-25 with categories.
Prospects For Antisense Nucleic Acid Therapy Of Cancer And Aids
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Author : Eric Wickstrom
language : en
Publisher: Wiley-Liss
Release Date : 1991-10-18
Prospects For Antisense Nucleic Acid Therapy Of Cancer And Aids written by Eric Wickstrom and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-10-18 with Medical categories.
A wide range of new technology involving a direct genetic approach to the treatment of disease using nucleic acid therapeutics is the main focus of this absorbing book. Provides in-depth coverage of the rapid progress of this new technology, from its theoretical stage to its current position at the verge of experimental applications, along with provocative discussions of the therapeutic implications.
Rna Therapeutics
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Author : Paloma H. Giangrande
language : en
Publisher: Academic Press
Release Date : 2022-04-10
Rna Therapeutics written by Paloma H. Giangrande and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-10 with Science categories.
RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development. Features leading experts in the field of RNA therapeutics, spanning all classes of RNA therapies Provides a detailed examination of approved RNA therapies and lessons learned from failed therapeutics Covers all aspects of therapeutic discovery and preclinical development, as well as clinical translation, manufacturing and regulatory aspects
Pharmaceutical Perspectives Of Nucleic Acid Based Therapy
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Author : Ram I. Mahato
language : en
Publisher: CRC Press
Release Date : 2002-06-27
Pharmaceutical Perspectives Of Nucleic Acid Based Therapy written by Ram I. Mahato and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-27 with Medical categories.
Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in
Rna Therapeutics Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-03-06
Rna Therapeutics Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-06 with Science categories.
RNA Therapeutics, Part B, Volume 204 updates on a new class of medication based on RNA molecules, with chapters on a variety of topics, including RNA therapeutics for cardiovascular disorders, RNA therapeutics for kidney injury, RNA therapeutics for beta-thalassemia, RNA therapeutics for infectious diseases, RNA therapeutics for reproductive diseases, Potential of RNA and transcriptomic data to drive drug repurposing for various diseases, RNA therapeutics for glioma/glioblastoma, RNA therapeutics for regenerative medicine, Advances in the liposome-based delivery systems for RNA therapeutics in cancer, Advances in the polymeric nanoparticulate delivery systems for RNA therapeutics in cancer, and more. Covers RNA therapeutics' history and future perspectives Discusses the processes of RNA therapeutical development Presents recent applications of RNA therapeutic in clinics Provides the advantages and disadvantages of RNA therapeutics
Nucleic Acids As Gene Anticancer Drug Delivery Therapy
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Author : Loutfy H. Madkour
language : en
Publisher: Academic Press
Release Date : 2019-08-27
Nucleic Acids As Gene Anticancer Drug Delivery Therapy written by Loutfy H. Madkour and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Business & Economics categories.
Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research. Discusses intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery Contains a comprehensive comparison of various delivery systems, listing their advantages and limitations Presents combination therapy as a new hope for enhancing current gene-based treatment efficacy
Nucleic Acid Biology And Its Application In Human Diseases
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Author : Subhrangsu Chatterjee
language : en
Publisher: Springer Nature
Release Date : 2023-05-30
Nucleic Acid Biology And Its Application In Human Diseases written by Subhrangsu Chatterjee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-30 with Medical categories.
This book reviews the structure-function relationship of nucleic acids, their role in the pathophysiology of the diseases, and as therapeutic targets for human diseases. The chapters discuss the role of nucleic acids in inflammatory diseases, neurodegenerative diseases, and cancer. The book also describes recent advancements in nucleic acid-based therapy, the application of nucleic acids in diagnostics, in the development of nano-carriers, logic gates, and sensors. It explores the use of nucleic acids (RNA and DNA) as a unique and multifunctional platform for numerous applications, including therapeutics, diagnostics, nanodevices, and materials. It further examines the role of DNA methylation, histone modifiers and readers, chromatin remodelers, microRNAs, and other components of chromatin in the progression of cancer. The book also discusses the applications of nucleic acid as a vaccine and as a gene-editing tool. It also provides an overview of the clinical trials using genome editing platforms for disease treatment and the challenges in implementing the editing technology. Finally, the book elucidates a representative description of challenges associated with nucleic acid-mediated therapy.
Advances In Nucleic Acid Therapeutics
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Author : Michael J Gait
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-02-11
Advances In Nucleic Acid Therapeutics written by Michael J Gait and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-11 with Science categories.
The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a comprehensive review of the latest advances in the field, covering the background of the development of nucleic acids for therapeutic purposes to the array of drug development approaches currently being pursued using antisense, RNAi, aptamer, immune modulatory and other synthetic oligonucleotides. Nucleic acid therapeutics is a field that has been continually innovating to meet the challenges of drug discovery and development; bringing contributions together from leaders at the forefront of progress, this book depicts the many approaches currently being pursued in both academia and industry. A go-to volume for medicinal chemists, Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery.
Antisense Therapy
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Author : Shashwat Sharad
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-11-20
Antisense Therapy written by Shashwat Sharad and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-20 with Medical categories.
Antisense Therapy offers a comprehensive, state-of-the art perspective on the role of antisense therapy in the treatment of human disease, with a special focus on cancer. Use of antisense oligonucleotides is a growing field of pharmaceutical and biotech companies and research programs for treatment of several diseases. This book summarizes and presents the best updates, therapeutic principles, methods, and applications in the field and offers meaningful information to move treatment discovery forward.