Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 427 Skin Absorption In Vivo Method


Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 427 Skin Absorption In Vivo Method
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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 427 Skin Absorption In Vivo Method


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 427 Skin Absorption In Vivo Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2004-11-23

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 427 Skin Absorption In Vivo Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-23 with categories.


The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 427 Skin Absorption In Vivo Method


Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 427 Skin Absorption In Vivo Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2004-11-23

Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 427 Skin Absorption In Vivo Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-23 with categories.


The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 428 Skin Absorption In Vitro Method


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 428 Skin Absorption In Vitro Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2004-11-23

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 428 Skin Absorption In Vitro Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-23 with categories.


This Test method has been designed to provide information on absorption of a test substance, (ideally radiolabelled), applied to the surface of a skin sample separating the two chambers (a donor chamber and a receptor chamber) of a diffusion cell ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 439 In Vitro Skin Irritation Reconstructed Human Epidermis Test Method


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 439 In Vitro Skin Irritation Reconstructed Human Epidermis Test Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2021-06-17

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 439 In Vitro Skin Irritation Reconstructed Human Epidermis Test Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-17 with categories.


This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2.



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 404 Acute Dermal Irritation Corrosion


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 404 Acute Dermal Irritation Corrosion
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2015-07-28

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 404 Acute Dermal Irritation Corrosion written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-28 with categories.


This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. It recommends sequential testing strategies, which include the performance of validated and accepted in vitro or ex vivo tests for corrosion/irritation.



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 410 Repeated Dose Dermal Toxicity 21 28 Day Study


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 410 Repeated Dose Dermal Toxicity 21 28 Day Study
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 1981-05-12

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 410 Repeated Dose Dermal Toxicity 21 28 Day Study written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-05-12 with categories.


This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 411 Subchronic Dermal Toxicity 90 Day Study


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 411 Subchronic Dermal Toxicity 90 Day Study
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 1981-05-12

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 411 Subchronic Dermal Toxicity 90 Day Study written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-05-12 with categories.


This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 435 In Vitro Membrane Barrier Test Method For Skin Corrosion


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 435 In Vitro Membrane Barrier Test Method For Skin Corrosion
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2015-07-28

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 435 In Vitro Membrane Barrier Test Method For Skin Corrosion written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-28 with categories.


This updated Test Guideline 435 provides an in vitro membrane barrier test method that can be used to identify corrosive chemicals. The test method utilizes an artificial membrane designed to respond to corrosive chemicals in a manner similar to animal skin in situ.



Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Document For The Conduct Of Skin Absorption Studies


Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Document For The Conduct Of Skin Absorption Studies
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2004-11-01

Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Document For The Conduct Of Skin Absorption Studies written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-01 with categories.


This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 417 Toxicokinetics


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 417 Toxicokinetics
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2010-07-23

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 417 Toxicokinetics written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-23 with categories.


This Test Guideline describes in vivo studies that provide information on mass balance, absorption, bioavailability, tissue distribution, metabolism, excretion, and basic toxicokinetic parameters [e.g. AUC], as well as supplemental approaches that ...