Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 440 Uterotrophic Bioassay In Rodents A Short Term Screening Test For Oestrogenic Properties

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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 440 Uterotrophic Bioassay In Rodents A Short Term Screening Test For Oestrogenic Properties
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2007-10-15
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 440 Uterotrophic Bioassay In Rodents A Short Term Screening Test For Oestrogenic Properties written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-15 with categories.
The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 456 H295r Steroidogenesis Assay
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2025-06-25
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 456 H295r Steroidogenesis Assay written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with categories.
This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 407 Repeated Dose 28 Day Oral Toxicity Study In Rodents
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2025-06-25
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 407 Repeated Dose 28 Day Oral Toxicity Study In Rodents written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with categories.
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 443 Extended One Generation Reproductive Toxicity Study
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2025-06-25
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 443 Extended One Generation Reproductive Toxicity Study written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with categories.
This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...
Reproductive And Developmental Toxicology
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Author : Ramesh C. Gupta
language : en
Publisher: Academic Press
Release Date : 2022-02-11
Reproductive And Developmental Toxicology written by Ramesh C. Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-11 with Medical categories.
**Selected for Doody's Core Titles® 2024 in Toxicology**Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
Regulatory Toxicology In The European Union
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Author : Tim Marrs
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-02-21
Regulatory Toxicology In The European Union written by Tim Marrs and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-21 with Medical categories.
Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of the principles of regulatory toxicology and their application and presents the relationship between toxicology and legislative processes in regulating chemical commodities across Europe. This title has a broad scope, covering historical and current chemical regulation in Europe, the role of European agencies and institutions, and also the use of toxicology data for important classes of chemicals, including human and veterinary medicines, animal feed and food additives, biocides, pesticides and nanomaterials. This book is therefore extremely pertinent and timely in the toxicology field at present. This book is an essential reference for regulatory authorities, industrialists, academics, undergraduates and postgraduates working within safety and hazards, toxicology, the biological sciences, and the medicinal and pharmaceutical sciences across the European Union.
Toxicologic Pathology
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Author : Page R. Bouchard
language : en
Publisher: CRC Press
Release Date : 2025-06-23
Toxicologic Pathology written by Page R. Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-23 with Medical categories.
The new edition provides practical and timely information for toxicologic pathologists working in drug discovery and development. The introductory concept chapters are consolidated into two more concise and better-organized introductory chapters. The two concept chapters introduce the reader to pharmaceutical R&D, the role of the pathologist in the process, and critical partner scientific disciplines with whom the pathologist will collaborate. In this revision, the organ system chapters incorporate more consistent commentary and guidance on the molecular mechanism of action, human translational relevance, and regulatory impact of pathological findings as they are described in these chapters. Key Features: Aids scientists in understanding spontaneously occurring and compound-related pathological findings Features three new well-respected scientists on the editorial team Includes more consistent commentary and guidance in the organ system chapters
Test No 440 Uterotrophic Bioassay In Rodents A Short Term Screening Test For Oestrogenic Properties Korean Version
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Author : OECD
language : ko
Publisher: OECD Publishing
Release Date : 2009-07-16
Test No 440 Uterotrophic Bioassay In Rodents A Short Term Screening Test For Oestrogenic Properties Korean Version written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-16 with categories.
Endocrine Toxicology
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Author : J. Charles Eldridge
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Endocrine Toxicology written by J. Charles Eldridge and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology's increased importance in environmental safety issues
Test No 455 The Stably Transfected Human Estrogen Receptor Alpha Transcriptional Activation Assay For Detection Of Estrogenic Agonist Activity Of Chemicals
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2009-09-08
Test No 455 The Stably Transfected Human Estrogen Receptor Alpha Transcriptional Activation Assay For Detection Of Estrogenic Agonist Activity Of Chemicals written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-08 with categories.
This Test Guideline describes an in vitro assay, which provides mechanistical information, and can be used for screening and prioritization purposes. The test system utilises the hERalpha-HeLa-9903 cell line derived from a human cervical tumor and ...