Reproductive And Developmental Toxicology


Reproductive And Developmental Toxicology
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Reproductive And Developmental Toxicology


Reproductive And Developmental Toxicology
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Author : Ramesh C. Gupta
language : en
Publisher: Academic Press
Release Date : 2011-04-04

Reproductive And Developmental Toxicology written by Ramesh C. Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-04 with Medical categories.


Reproductive toxicology is a complex subject dealing with three components—parent, placenta, and fetus—and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife. Provides a complete, integrated source of information on the key risk stages during reproduction and development Includes coverage of emerging science such as stem cell application, toxicoproteomics, metabolomics, phthalates, infertility, teratogenicity, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis



Reproductive And Developmental Toxicology


Reproductive And Developmental Toxicology
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Author : Ramesh C. Gupta
language : en
Publisher: Academic Press
Release Date : 2017-03-24

Reproductive And Developmental Toxicology written by Ramesh C. Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-24 with Medical categories.


Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components—parent, placenta, and fetus—and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Includes new chapters covering significant developments, such as dose-response assessment for developmental toxicity, juvenile toxicity, and neural tube defects, as well as emerging science, such as stem cell application, toxicoproteomics, metabolomics, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis



Developmental And Reproductive Toxicology


Developmental And Reproductive Toxicology
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Author : Ronald D. Hood
language : en
Publisher: CRC Press
Release Date : 2005-08-30

Developmental And Reproductive Toxicology written by Ronald D. Hood and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-30 with Medical categories.


Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e



Reproductive And Developmental Toxicology


Reproductive And Developmental Toxicology
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Author : Kenneth S . Korach
language : en
Publisher: CRC Press
Release Date : 1998-03-27

Reproductive And Developmental Toxicology written by Kenneth S . Korach and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-03-27 with Medical categories.


This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproducti



Computational Methods For Reproductive And Developmental Toxicology


Computational Methods For Reproductive And Developmental Toxicology
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Author : Donald R. Mattison
language : en
Publisher: CRC Press
Release Date : 2015-12-02

Computational Methods For Reproductive And Developmental Toxicology written by Donald R. Mattison and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-02 with Medical categories.


Building from the perspective of reproductive and developmental biology, Computational Methods for Reproductive and Developmental Toxicology provides a timely and comprehensive overview of approaches in reproductive and developmental toxicology. The book, which is part of the QSAR in Environmental and Health Sciences series, is divided into three broad sections. The first provides a review of methods and approaches to meet the need for safety assessments in product development and regulatory approaches for environmental chemicals. The next one reviews the biological processes and endpoints involved in reproduction and development. The final and largest section summarizes protocols for evaluating biological processes and endpoints within reproduction and development. It also discusses informatics resources and computational methods. The book takes a cross-disciplinary approach bringing together developmental, reproductive and systems biology, chemistry, toxicology, pharmacology, biostatistics, information sciences, bioinformatics, and computational approaches. This valuable resource provides those in the field with the necessary knowledge to evaluate both classic and recent approaches to characterize toxicity.



Evaluating Chemical And Other Agent Exposures For Reproductive And Developmental Toxicity


Evaluating Chemical And Other Agent Exposures For Reproductive And Developmental Toxicity
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2001-04-13

Evaluating Chemical And Other Agent Exposures For Reproductive And Developmental Toxicity written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-13 with Nature categories.


The United States Navy has been concerned for some time with protecting its military and civilian personnel from reproductive and developmental hazards in the workplace. As part of its efforts to reduce or eliminate exposure of Naval personnel and their families to reproductive and developmental toxicants, the Navy requested that the National Research Council (NRC) recommend an approach that can be used to evaluate chemicals and physical agents for their potential to cause reproductive and developmental toxicity. The NRC assigned this project to the Committee on Toxicology, which convened the Subcommittee on Reproductive and Developmental Toxicology, to prepare this report. In this report, the subcommittee recommends an approach for evaluating agents for potential reproductive and developmental toxicity and demonstrates how that approach can be used by the Navy. This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the NRC's Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report: James Chen (National Center for Toxicological Research), George Daston (Procter and Gamble Company), Jerry Heindel (National Institute of Environmental Health Sciences), Grace Lemasters (University of Cincinnati), and John Young (National Center for Toxicological Research).



Reproductive And Developmental Toxicants


Reproductive And Developmental Toxicants
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Author : Eleanor Chelimsky
language : en
Publisher: DIANE Publishing
Release Date : 2000

Reproductive And Developmental Toxicants written by Eleanor Chelimsky and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.


Evaluates federal regulatory actions on environmental chemicals known to cause adverse reproductive and developmental outcomes. Identifies 30 environmental chemicals found to be of high concern because of the widespread acknowledgment of their reproductive and developmental consequences as toxicants. Determines the extent to which these chemicals are regulated by the federal government. Assesses the degree to which these regulatory actions are based on reproductive and developmental toxicity. Evaluates whether the regulatory protection currently provided to the public against reproductive and developmental disease is sufficient.



Reproductive Toxicology


Reproductive Toxicology
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Author : Jesús del Mazo
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Reproductive Toxicology written by Jesús del Mazo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.


Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.



Reproductive Toxicology


Reproductive Toxicology
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Author : Robert W. Kapp
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Reproductive Toxicology written by Robert W. Kapp and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology's contributors are experienced regulatory agency and Clinical Research Organization representatives w



Developmental And Reproductive Toxicology


Developmental And Reproductive Toxicology
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Author : Ali S. Faqi
language : en
Publisher: Humana
Release Date : 2018-06-15

Developmental And Reproductive Toxicology written by Ali S. Faqi and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Medical categories.


This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part of the safety assessment process for compounds with potential use in women of childbearing age or females that might be exposed during pregnancy as well as men of reproductive potential. The in vivo assessments included here are guideline-driven and are required for submissions for product approval. Written for the Methods in Pharmacology and Toxicology series, this collection includes the kind of detailed implementation advice necessary for success in the lab. Authoritative and practical, Developmental and Reproductive Toxicology is an ideal resource for researchers working in this vital field of study./div