Off The Target

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The Waiting Rooms

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Author : Eve Smith
language : en
Publisher: Orenda Books
Release Date : 2020-04-09

The Waiting Rooms written by Eve Smith and has been published by Orenda Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-09 with Fiction categories.

Swinging from South Africa to England: one woman's hunt for her birth mother in an all-too-believable near future in which an antibiotic crisis has decimated the population. A prescient, thrilling debut. 'Combines the excitement of a medical thriller à la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible, but written with such humanity and emotion' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy ________________ Decades of spiralling drug resistance have unleashed a global antibiotic crisis. Ordinary infections are untreatable, and a scratch from a pet can kill. A sacrifice is required to keep the majority safe: no one over seventy is allowed new antibiotics. The elderly are sent to hospitals nicknamed 'The Waiting Rooms' ... hospitals where no one ever gets well. Twenty years after the crisis takes hold, Kate begins a search for her birth mother, armed only with her name and her age. As Kate unearths disturbing facts about her mother's past, she puts her family in danger and risks losing everything. Because Kate is not the only secret that her mother is hiding. Someone else is looking for her, too. Sweeping from an all-too-real modern Britain to a pre-crisis South Africa, The Waiting Rooms is epic in scope, richly populated with unforgettable characters, and a tense, haunting vision of a future that is only a few mutations away. ________________ 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews 'A touching, gut-wrenching story of family mystery and tragedy ... a thriller that punches on two fronts – heart AND mind' The Sun 'Gripping and disturbing ... the medical research is convincing, the scenarios plausible, and the story is emotionally engaging. This is an incredible debut!' Gill Paul 'If the themes are dark and topical, the writing is exquisite. Breath held, I got to the finale with my heart in my mouth. Eve Smith weaves a complex and clever tale, merging countries and timelines; the result is a superb and satisfying novel' Louise Beech 'Margaret Atwood is one of my all-time writing heroes and The Handmaid's Tale is probably the best book I've ever read. Eve Smith and The Waiting Rooms really do challenge that long-held crown...' Random Things through My Letterbox 'Thoroughly engaging ... an eye-opening read' Crime Fiction Lover 'A novel of our times' Trip Fiction 'Haunting, honest and horrifying in its reality ... An epic and thrilling read' Book Literati 'Stunning dystopian debut. A prescient and alarming tale that seems just a whisper from reality' Suzy Apsley ' The Waiting Rooms will certainly distract us from the real world for a few hours and this is the immeasurable value of fiction. It gives hope that, as in Eve Smith's fictitious world, the possibility of a happy ending still exists' Die Burger ' The Waiting Rooms is a seriously impressive debut, a novel that is intuitive and chilling, one that will resonate with all in this current climate' Swirl & Thread

Off The Target

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Author : Muhammad Ali Nasir
language : en
Publisher: Springer Nature
Release Date : 2021-11-23

Off The Target written by Muhammad Ali Nasir and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-23 with Political Science categories.

This book describes the history of European integration and the Eurozone, before presenting ways in which the European Union can move forward. Charting integration from before the Second World War, the foundations of the Eurozone are examined to provide insight into the challenges faced by the European Union, including the Global Financial Crisis, over recent decades. The impact of TARGET2 and the European Monetary System are also discussed. This book aims to highlight ways that current challenges to European integration, such as the COVID-19 crisis, environmental degradation, and fiscal debt, can be overcome to promote economic growth and social advancement. It will be relevant to students, researchers, and policymakers interested in the political economy and European economic policy.

Off Target

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Author : Jill Ammon Vanderwood
language : en
Publisher: Human Rights Watch
Release Date : 2019-01-28

Off Target written by Jill Ammon Vanderwood and has been published by Human Rights Watch this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-28 with Juvenile Nonfiction categories.

What would you do if your friend showed you a gun?You are new in town and it's your first day at a new school. Your neighbor, Trevor introduces you to a group of three boys and two girls. Right away you notice that Eric, one of the guys in the group, is being bullied at school. When you go to Eric's house with your new friends, he shows the group a fully loaded handgun that is left in his mother's nightstand. You are faced with some hard choices when someone suggests that Eric should take the gun to school.___________________________________________What should you do? It's time to choose a path: If you're worried that Eric will take the gun to school-continue on page 7.If you decide to take the gun to prevent anyone from being hurt-continue on page 9.If you leave the house with the others and plan to come back for target practice the next day-continue on page 10.____________________________________________Off Target is the first book in The Path You Choose series. You, the reader determine the outcome by the choices you make. Once you read one story, go back and choose a different story. There are thirteen possible endings in this book.What path will you choose

Final Target

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Author : Iris Johansen
language : en
Publisher: Bantam
Release Date : 2007-12-18

Final Target written by Iris Johansen and has been published by Bantam this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-18 with Fiction categories.

The President’s daughter... The women determined to save her... The man with the power to betray a nation... Melissa Riley arrives at her sister’s isolated Virginia country home to find herself plunged into a deadly drama. There the renowned Dr. Jessica Riley is attempting to draw the daughter of the President of the United States out of a severe catatonic trauma. The last thing young Cassie Andreas saw was an organized team ruthlessly murder her nanny and the Secret Service agents sworn to protect her. But to free Cassie, Melissa and Jessica must trust a mysterious, charismatic man. Michael Travis made his fortune in the international underworld. He risked everything to save Cassie during that terrible night of bloodshed. And he has entered into a secret bargain with the President. But is his show of concern all a treacherous charade? Melissa and Jessica have no choice but to accept Travis as their ally—and to follow a dangerous plan that will lead them into the world of a killer who’ll destroy anyone standing between him and the...Final Target.

Target 100

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Author : Liz Josefsberg
language : en
Publisher: BenBella Books
Release Date : 2017-12-19

Target 100 written by Liz Josefsberg and has been published by BenBella Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-19 with Health & Fitness categories.

"When I was losing weight, Liz was more than my coach; she was my rock, and I couldn't have done it without her. She just got it, because she'd been through it herself (and helped about a million other people through it, too). Target 100 is Liz in book form—smart, supportive, and full of practical, simple solutions. Liz changed my life and my whole concept of dieting—and now can change, yours too." —Jessica Simpson When did weight loss get so complicated? Today, it feels like there are a million different apps, tools, workouts, and eating plans designed to help you lose weight. Some promise success via drastic, unlivable restrictions, others are so complex they turn losing weight into a second job. In Target 100, celebrity weight-loss coach Liz Josefsberg shows you don't have to be a slave to your weight-loss program. You don't have to count every gram of every nutrient and every calorie you eat at every meal. Believe it or not, weight loss can be simple. It can even be . . . fun. A 15-year veteran of the weight-loss industry and who lost—and kept off—65 pounds herself, Liz has accrued a high-profile clientele. She helped Oscar-winner Jennifer Hudson lose weight and transform her life and coached Jessica Simpson to shed over 50 pounds of baby weight (twice!). But along with the likes of Charles Barkley and Katie Couric, Josefsberg has also coached thousands of others, everyone from stay-at-home moms to office jockeys. Along the way, she's learned what works—and what doesn't—when it comes to lasting weight loss, and she's ready to share her secrets with the rest of us. Target 100 streamlines the weight-loss process into six easy-to-follow guidelines and shows you how to adjust them to fit your lifestyle, personalizing the program so that it works for you. Josefsberg offers tips, worksheets, and powerful insights to help you fine-tune a range of weight-related behaviors, from battling stress to getting more sleep, setting the stage for permanent, long-term weight loss. Instead of counting calories, you'll learn how simple changes come together to jumpstart your health and wellbeing, such as: Drinking 100 ounces of water a day Exercising for 100 minutes a week Adding 100 minutes of Sleep a week De-Stressing for 100 minutes a week And more! Warm and no-nonsense, encouraging and informative, Target 100 is a holistic and revolutionary wellness book with a simple message: You don't need to be perfect to lose weight, or transform yourself into someone you're not. You can lose weight for good, with the world's simplest weight loss program.

The Actor And The Target

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Author : Declan Donnellan
language : en
Publisher:
Release Date : 2002

The Actor And The Target written by Declan Donnellan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Acting categories.

Declan Donnellan's fresh and radical approach to acting takes a scalpel to the heart of actor's persistent fears from . . . I don't know what I'm doing through I don't know who I am to I don't know what I'm playing. The Actor and the Target has already been hailed by the press in Russia where it is already published: Practically and modestly written, Declan Donnellan's book helps actors to release their talent to be free on stage. However Donnellan's path leads to wider perspectives, his book is rooted in modern theatre, modern psychology and, above all, modern reality. Written with grace and elegance, The Actor and the Target will be thoroughly enjoyed not only by the actors of the new millennium, but also by those of us who see the stage from the dark auditorium.-IzvestiaDonnellan's directing style is immediately recognizable in his book, drenched in its spirit of artistic and personal freedom. Unpretentious, straightforward, and pierced with acute insight.-KommersantClearly and systematically laid out and full of firm and unambiguous precepts, this book will become a bible for actors in the 21st century.Declan Donnellan is the first Director of the Royal Shakespeare Academy and is best known for his work with Check By Jowl, including As You Like It, and the recent production of Homebody/Kabul in New York. As Associate Director of the National Theatre his pro-ductions included Fuente Ovejuna, Sweeney Todd, and Angels in America. Abroad, his work abroad includes Le Cid for the Avignon Festival, The Winter's Tale for the Maly Theatre in St. Petersbourg and Puskin's Boris Godunuv for the Moscow Theatre confederation. He has received awards in London, Paris, New York, and Moscow.

Nanomedical Drug Delivery For Neurodegenerative Diseases

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Author : Awesh K. Yadav
language : en
Publisher: Academic Press
Release Date : 2022-03-10

Nanomedical Drug Delivery For Neurodegenerative Diseases written by Awesh K. Yadav and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-10 with Medical categories.

Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. - Includes design, synthesis and applications of drug delivery systems - Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders - Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases - Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems - Details how nanocarrier-based delivery is useful to improve efficacy and cure

Precision Medicine For Investigators Practitioners And Providers

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Author : Joel Faintuch
language : en
Publisher: Academic Press
Release Date : 2019-11-16

Precision Medicine For Investigators Practitioners And Providers written by Joel Faintuch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Science categories.

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. - Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers - Covers disease groups and ancillary information about techniques, resources and consequences - Follows a structured blueprint, ensuring essential chapters items are not overlooked

Rna Based Technologies For Functional Genomics In Plants

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Author : Guiliang Tang
language : en
Publisher: Springer Nature
Release Date : 2021-04-11

Rna Based Technologies For Functional Genomics In Plants written by Guiliang Tang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-11 with Science categories.

This book offers a unique and comprehensive overview of key RNA-based technologies, as well as their development and applications for the functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on small RNAs, long non-coding RNAs and protein-coding genes. These techniques chiefly focus on target mimics (TMs) and short tandem target mimics (STTMs) for small RNAs, and artificial microRNAs (amiRNAs), RNA interference (RNAi) and CRISPR/Cas for genes. Furthermore, the book discusses the latest trends in the field and various modifications of the above-mentioned approaches, and explores how these RNA-based technologies have been developed, applied and validated as essential technologies in plant functional genomics. RNA-based technologies, their mechanisms of action, their advantages and disadvantages, and insights into the further development and applications of these technologies in plants are discussed. These techniques will enable the users to functionally characterize genes and small RNAs through silencing, overexpression and editing. Gathering contributions by globally respected experts, the book will appeal to students, teachers and scientists in academia and industry who are interested in horticulture, genetics, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture & genetic engineering, and functional genomics.

The Epigenetics Of Autoimmunity

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Author : Rongxin Zhang
language : en
Publisher: Academic Press
Release Date : 2018-04-25

The Epigenetics Of Autoimmunity written by Rongxin Zhang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-25 with Medical categories.

The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sjögren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment. - Provides the accurate and cutting-edge information on autoimmunity epigenetics - Wide coverage appeals to those interested in fundamental epigenetics and inheritance to those with more clinical interests - Critical reviews of the mean of deriving and analysing autoimmunity epigenetics information as well as its translational potential - Up-to-date coverage of emerging topics in autoimmunity epigenetics