On The Origin And Function Of Human Nk Like Cd8 T Cells Charting New Territories
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On The Origin And Function Of Human Nk Like Cd8 T Cells Charting New Territories
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Author : Fernando A. Arosa
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-25
On The Origin And Function Of Human Nk Like Cd8 T Cells Charting New Territories written by Fernando A. Arosa and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-25 with categories.
Human CD8+ T cells expressing NK receptors and receptors found on innate immune cells, and designated as NK-like or innate CD8+ T cells, have been long considered as terminally differentiated lymphocytes responsible for tissue inflammation and destruction. However, a growing body of knowledge is unveiling that NK-like CD8+ T cells have many, sometimes contrasting, functions. The limited knowledge of the biology of this type of CD8+ T cells and the role they play within peripheral tissues and organs under homeostatic conditions has hampered our understanding of disease and therefore the possible development of disease diagnostic tools and effective immunotherapies. In this Research Topic are presented a variety of topics and views, some of them overlooked for many years, on human NK-like CD8+ T cells, which may open new and novel avenues of research to further our understanding of these polyfunctional T cells.
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 2000
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Environmental health categories.
Code Of Federal Regulations
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Author :
language : en
Publisher:
Release Date : 2011
Code Of Federal Regulations written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Environmental law categories.
Special edition of the Federal Register, containing a codification of documents of general applicability and future effect as of July 1, ... with ancillaries.
The Code Of Federal Regulations Of The United States Of America
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Author :
language : en
Publisher:
Release Date : 2005
The Code Of Federal Regulations Of The United States Of America written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Administrative law categories.
The Code of Federal Regulations is the codification of the general and permanent rules published in the Federal Register by the executive departments and agencies of the Federal Government.
Code Of Federal Regulations Title 40 Protection Of Environment Pt 790 999 Revised As Of July 1 2011
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Author :
language : en
Publisher: Government Printing Office
Release Date : 2011-08-29
Code Of Federal Regulations Title 40 Protection Of Environment Pt 790 999 Revised As Of July 1 2011 written by and has been published by Government Printing Office this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-29 with Law categories.
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus
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Author : Wantao Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-20
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus written by Wantao Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-20 with Medical categories.
The interplay between cancer cells and the immune system is a critical area of research, with recent advancements highlighting the potential of immunotherapy in offering durable responses across various cancer types. Immune checkpoint inhibitors, in particular, have emerged as a cornerstone of cancer therapy, transforming patient outcomes. However, the heterogeneity of tumor-immune interactions poses significant challenges, with a considerable fraction of patients not responding to such treatments. This underscores the urgent need for a deeper understanding of the molecular and cellular underpinnings of these interactions, to harness the full potential of immunotherapy. This Research Topic aims to address the complex landscape of tumor-immune interactions, focusing on identifying and leveraging novel biomarkers and mechanisms that can predict and enhance the efficacy of immunotherapy. Given the pivotal role of the immune system in controlling and eradicating cancer, understanding these interactions at a granular level could lead to more personalized and effective treatment strategies. Recent advances in technologies such as next-generation sequencing, single-cell RNA sequencing, and mass cytometry have opened new avenues for dissecting the complexity of the tumor microenvironment and immune evasion strategies. This collection seeks to compile cutting-edge research that employs these technologies to uncover new biomarkers, understand resistance mechanisms, and identify potential therapeutic targets within the immune contexture of tumors. By bridging gaps in knowledge and fostering innovation, this topic aims to propel the field towards more predictive and responsive immunotherapy approaches.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2003
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Dissertations, Academic categories.
Harrison S Principles Of Internal Medicine Twenty First Edition Vol 1 Vol 2
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Author : Joseph Loscalzo
language : en
Publisher: McGraw Hill Professional
Release Date : 2022-04-05
Harrison S Principles Of Internal Medicine Twenty First Edition Vol 1 Vol 2 written by Joseph Loscalzo and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-05 with Medical categories.
The Voice of Clinical ReasonA Doody's Core Title for 2024 & 2023! Harrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text—and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. Harrison's Principles of Internal Medicine stands as the benchmark for authoritative, practical information on patient care and the pathogenesis and clinical management of symptoms and signs and specific diseases. Written and edited by the world’s top experts in their respective fields, this landmark guide provides the comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. Harrison’s is world-renowned as the most authoritative source for: • Descriptions of disease mechanisms and how the clinician can apply that knowledge for the best patient care and optimal diagnosis and treatment of specific diseases • Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases • The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow • Updated clinical trial results and recommended guidelines • Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings • Coverage of both therapeutic approaches and specific treatment regimens • Practical clinical decision trees and algorithms • Organ-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, general and specific approaches to therapy Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition: • Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer • Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries • More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes • More than a dozen atlases featuring curated collections of visual aspects of diagnosis and management • Complete, updated curation and synthesis of primary medical literature which incorporates current data from major studies and clinical trials • Clinical reasoning resources and helpful disease/presentation schemas • Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms
Science Citation Index
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Author :
language : en
Publisher:
Release Date : 1992
Science Citation Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.
Vols. for 1964- have guides and journal lists.
Nk Cell Subsets In Health And Disease New Developments
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Author : Emanuela Marcenaro
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-29
Nk Cell Subsets In Health And Disease New Developments written by Emanuela Marcenaro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-29 with categories.
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.