Optical Coherence Tomography In Multiple Sclerosis
DOWNLOAD eBooks
Download Optical Coherence Tomography In Multiple Sclerosis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Optical Coherence Tomography In Multiple Sclerosis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Optical Coherence Tomography In Multiple Sclerosis
DOWNLOAD eBooks
Author : Axel Petzold
language : en
Publisher: Springer
Release Date : 2015-08-28
Optical Coherence Tomography In Multiple Sclerosis written by Axel Petzold and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-28 with Medical categories.
This book gives a clinical context to optical coherence tomography (OCT) findings, while considering the differential diagnosis and providing patient management guidance. Relevant anatomical and technical aspects are discussed, followed by a pragmatic illustration of the use of OCT for the clinical spectrum of multiple sclerosis and optic neuritis, and finishing with information on monitoring ocular side effects of recently approved disease-modifying treatments in multiple sclerosis. Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications is aimed at clinical neurologists working with patients suffering from MS and general neurologists who see patients with visual symptoms in their daily practice. Ophthalmologists sharing clinical responsibilities with neurologists for patients under disease-modifying treatments will also find the book of interest.
Optical Coherence Tomography In Multiple Sclerosis
DOWNLOAD eBooks
Author :
language : en
Publisher:
Release Date : 2021
Optical Coherence Tomography In Multiple Sclerosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) affecting more than two million people worldwide. The disease is characterised by inflammation in the CNS (leading to episodes of focal neurological dysfunction, i.e. relapses) and neurodegeneration (leading to progressive and permanent disability). Depending on the localisation of the CNS damage, patients exhibit a wide range of symptoms including muscle weakness, sensory disturbances, problems with coordination, fatigue and cognitive impairment. Visual symptoms are common as well, with more dan 50% of MS patients experiencing one or more episodes of optic neuritis (ON) during the course of the disease. The disease course in MS is highly variable and difficult to predict. However, predicting the disease course is crucial for determining the proper treatment. This thesis focuses on how optical coherence tomography (OCT) can aid in monitoring and predicting the disease course in patients with MS. OCT is an imaging technique that generates high resolution images of the retina and all its layers. The inner two retinal layers consist of the retinal ganglion cells and their axons that will eventually form the optic nerve. Thereby, these two layers are directly connected to the brain. Previous research has demonstrated that previous episodes of ON result in atrophy (thinning) of these two layers. Sometimes, it can be challenging to establish whether a patient has ever experienced an episode of optic neuritis clinically. The absolute thickness of the retinal layers is not a good indicator for this. Our research shows that the difference in retinal layer thickness between the eyes of a single patient can, with high accuracy, discriminate ON patients from non-ON patients. Being able to establish the presence of a previous episode of ON in this way, might lead to an earlier diagnosis of MS and earlier treatment.
Optical Coherence Tomography In Neurologic Diseases
DOWNLOAD eBooks
Author : Peter A. Calabresi
language : en
Publisher: Cambridge University Press
Release Date : 2015-05-14
Optical Coherence Tomography In Neurologic Diseases written by Peter A. Calabresi and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-14 with Medical categories.
The first comprehensive review of the use of optical coherence tomography in neurological diseases for neurologists, neuro-ophthalmologists, and neuroradiologists.
Oct And Imaging In Central Nervous System Diseases
DOWNLOAD eBooks
Author : Andrzej Grzybowski
language : en
Publisher: Springer Nature
Release Date : 2020-01-01
Oct And Imaging In Central Nervous System Diseases written by Andrzej Grzybowski and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-01 with Medical categories.
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.
Oct And Imaging In Central Nervous System Diseases
DOWNLOAD eBooks
Author :
language : en
Publisher:
Release Date : 2020
Oct And Imaging In Central Nervous System Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Central nervous system categories.
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracranial hypertension, Friedreich's ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the "window to the brain".
Optical Coherence Tomography In Neurologic Diseases
DOWNLOAD eBooks
Author : Peter A. Calabresi
language : en
Publisher:
Release Date : 2015
Optical Coherence Tomography In Neurologic Diseases written by Peter A. Calabresi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with HEALTH & FITNESS categories.
"Optical coherence tomography (OCT) provides tissue morphology imagery at much higher resolution than other imaging modalities such as MRI or ultrasound, and the machines are comparatively cheaper. It is an easy technique to perform; is non-ionizing, and therefore safe. These benefits are driving a rapid transformation of OCT, from its principal application as a research tool, into an extension of the 'neurological examination' in routine office practice. Originally used in assessing the severity of tissue damage and prognosis of multiple sclerosis and various neuro-ophthalmic conditions, OCT is increasingly used in other neurological disorders such as Parkinson's disease, ALS, and Alzheimer's disease. This book is the first comprehensive review of the use of OCT in neurological diseases. The coverage includes a description of the technique and its utilization in a variety of neurologic conditions. Essential reading for neurologists, neuro-ophthalmologists, and neuroradiologists wanting an introductory account of the clinical applications of OCT"--Provided by publisher.
Oct In Central Nervous System Diseases
DOWNLOAD eBooks
Author : Andrzej Grzybowski
language : en
Publisher: Springer
Release Date : 2016-03-30
Oct In Central Nervous System Diseases written by Andrzej Grzybowski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-30 with Medical categories.
This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.
Optical Coherence Tomography To Measure Effects Of Autologous Mesenchymal Stem Cell Transplant In Multiple Sclerosis Patients
DOWNLOAD eBooks
Author : Ian Rossman
language : en
Publisher:
Release Date : 2017
Optical Coherence Tomography To Measure Effects Of Autologous Mesenchymal Stem Cell Transplant In Multiple Sclerosis Patients written by Ian Rossman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Mesenchymal stem cells categories.
Anterior visual pathway disease affects >50% of multiple sclerosis (MS) patients. Optical coherence tomography (OCT) monitors MS-related retinal degeneration. Retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thinning in MS correlates with clinical and visual disability, and brain atrophy. Mesenchymal stem cells (MSC) are immunomodulatory in MS animal models, targeting inflammatory CNS injury. A recent Cleveland Clinic phase 1 trial demonstrated feasibility/tolerability of autologous MSC transplant in MS patients. My study analyzed GCL and RNFL relationships with clinical, visual, and MRI measures, before and after MSC transplant. MSC transplant affected no differences from baseline to 6 months in GCL or RNFL thickness. Linear mixed effects models predicted significant, but modest GCL thickness increases following MSC transplant. Thus, MSC neuroprotection was indirectly modeled, but not directly measured clinically or radiographically. Future MSC trials in MS should utilize OCT, a sensitive biomarker for neurodegeneration and response to experimental neuroprotective agents.
High Resolution Imaging In Microscopy And Ophthalmology
DOWNLOAD eBooks
Author : Josef F. Bille
language : en
Publisher: Springer
Release Date : 2019-08-13
High Resolution Imaging In Microscopy And Ophthalmology written by Josef F. Bille and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Medical categories.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Optical Coherence Tomography
DOWNLOAD eBooks
Author : Wolfgang Drexler
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-10
Optical Coherence Tomography written by Wolfgang Drexler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-10 with Medical categories.
Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.