Optimal High Throughput Screening
DOWNLOAD
Download Optimal High Throughput Screening PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Optimal High Throughput Screening book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Optimal High Throughput Screening
DOWNLOAD
Author : Xiaohua Douglas Zhang
language : en
Publisher: Cambridge University Press
Release Date : 2011-02-21
Optimal High Throughput Screening written by Xiaohua Douglas Zhang and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-21 with Medical categories.
This concise, self-contained and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound basis. Combining ideas from biology, computing and statistics, the author explains experimental designs and analytic methods that are amenable to rigorous analysis and interpretation of RNAi HTS experiments. The opening chapters are carefully presented to be accessible both to biologists with training only in basic statistics and to computational scientists and statisticians with basic biological knowledge. Biologists will see how new experiment designs and rudimentary data-handling strategies for RNAi HTS experiments can improve their results, whereas analysts will learn how to apply recently developed statistical methods to interpret HTS experiments.
High Throughput Screening
DOWNLOAD
Author : William P. Janzen
language : en
Publisher: Methods in Molecular Biology
Release Date : 2009-07-09
High Throughput Screening written by William P. Janzen and has been published by Methods in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-09 with Juvenile Nonfiction categories.
Featuring new screening technologies as well as many well established methods, this book offers comprehensive treatment of the activities directly related to High Throughput Screening (HTS), such as compound library management, data handling, and robotics.
High Throughput Screening
DOWNLOAD
Author : Mark Wigglesworth
language : en
Publisher:
Release Date : 2020
High Throughput Screening written by Mark Wigglesworth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Technology & Engineering categories.
"High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the discovery of pharmaceutical start points. HTS remains one of the most successful approaches, and therefore an important foundation of drug discovery. In High Throughput Screening: Methods, Techniques and Applications, leading industrial and academic experts in screening and drug discovery explain key technologies and methods while demonstrating how they can be applied to successful hit identification. Describing both traditional and emerging methods in detail, this book provides an overview of these methods to the reader that will serve both those new to the field and expert scientists alike. High Throughput Screening: Methods, Techniques and Applications provides readers with an outline of key elements in the areas of assay development, detailed descriptions of a range of both biochemical and cell-based screening methodologies and strategies, as well as highlighting important steps in data analysis. By describing the basic principles of methods commonly used in HTS, High Throughput Screening: Methods, Techniques and Applications provides an illuminating introduction to HTS, capturing established good practice within the field, thereby imparting both the industrial and academic researcher with the knowledge required to work effectively in both today's and the hit identification laboratories of the future"--
High Throughput Screening Methods
DOWNLOAD
Author : Joshua A Bittker
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016-12-05
High Throughput Screening Methods written by Joshua A Bittker and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-05 with Medical categories.
High throughput screening remains a key part of early stage drug and tool compound discovery, and methods and technologies have seen many fundamental improvements and innovations over the past 20 years. This comprehensive book provides a historical survey of the field up to the current state-of-the-art. In addition to the specific methods, this book also considers cultural and organizational questions that represent opportunities for future success. Following thought-provoking foreword and introduction from Professor Stuart Schreiber and the editors, chapters from leading experts across academia and industry cover initial considerations for screening, methods appropriate for different goals in small molecule discovery, newer technologies that provide alternative approaches to traditional miniaturization procedures, and practical aspects such as cost and resourcing. Within the context of their historical development, authors explain common pitfalls and their solutions. This book will serve as both a practical reference and a thoughtful guide to the philosophy underlying technological change in such a fast-moving area for postgraduates and researchers in academia and industry, particularly in the areas of chemical biology, pharmacology, structural biology and assay development.
High Throughput Screening
DOWNLOAD
Author : G. K. Dixon
language : en
Publisher: Taylor & Francis
Release Date : 2000
High Throughput Screening written by G. K. Dixon and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Business & Economics categories.
High Throughput Screening is playing an ever-increasing role in the identification of lead compounds in the pharmaceutical and agrochemical industries. This book provides an up-to-date account of the area and should be of particular interest for managers from the pharmaceutical industry.
High Throughput Screening
DOWNLOAD
Author : John P. Devlin
language : en
Publisher: CRC Press
Release Date : 1997-05-06
High Throughput Screening written by John P. Devlin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-06 with Science categories.
Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.
High Throughput Screening In Chemical Catalysis
DOWNLOAD
Author : Alfred Hagemeyer
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
High Throughput Screening In Chemical Catalysis written by Alfred Hagemeyer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
In this first book to present every important aspect of this fascinating and developing field, the three editors A. Hagemeyer, P. Strasser and A. F. Volpe Jr. from Symyx Technologies have chosen a perfect mixture of distinguished, international authors from both academia and industry. Each chapter is devoted to a major topic - high-throughput experimentation methodologies, integrated combinatorial synthesis and screening workflow, and applications to chemical catalysts with an emphasis on heterogeneous catalysis, olefin polymerization and electrocatalysis for fuel cells. An indispensable source for everyone working in the field.
Mining High Throughput Screening Data To Accelerate Drug Lead Discovery
DOWNLOAD
Author : Anang A. Shelat
language : en
Publisher:
Release Date : 2005
Mining High Throughput Screening Data To Accelerate Drug Lead Discovery written by Anang A. Shelat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
In Chapter 4, we discuss the need to approach drug discovery as a multivariate optimization problem and describe the Assay Reporter---an informatics platform that integrates both chemical and biological information in order to identify "good" molecules suitable for further development. Future plans to introduce elements of computational learning into the Assay Reporter framework are detailed in Chapter 5.
Challenges And Issues In High Throughput Screening
DOWNLOAD
Author : G. K. Dixon
language : en
Publisher: Taylor & Francis
Release Date : 1998
Challenges And Issues In High Throughput Screening written by G. K. Dixon and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Agricultural chemicals categories.
Comprises of papers presented at the 'New Challenges Arising from High Throughput Screening' conference held in Manchester, July 1997; ; Discusses a technique of key importance in many pharmaceutical companies; ; Reveals all the latest developments to all
High Throughput Screening In Downstream Processing Of Biotechnological Products
DOWNLOAD
Author : Matthias Wiendahl
language : en
Publisher: Cuvillier Verlag
Release Date : 2008
High Throughput Screening In Downstream Processing Of Biotechnological Products written by Matthias Wiendahl and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.