Cell Based Assays For High Throughput Screening
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Cell Based Assays For High Throughput Screening
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Author : Paul A. Clemons
language : en
Publisher: Humana Press
Release Date : 2014-11-27
Cell Based Assays For High Throughput Screening written by Paul A. Clemons and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-27 with Science categories.
As the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing an easily accessible reference volume for cell-based phenotypic screening. Leading researchers in the field contribute state-of-the-art methods with actionable protocols covering four major areas of study: model biological systems, screening modalities and assay systems, detection technologies, and approaches to data analysis. Written in the highly successful Methods in Molecular BiologyTM series format, each chapter includes a brief introduction to the subject, lists of necessary materials and reagents, step-by-step laboratory protocols, and a Notes section detailing tips on troubleshooting and avoiding known pitfalls. Cutting-edge and easy-to-use, Cell-Based Assays for High-Throughput Screening: Methods and Protocols presents an overview of relevant approaches, enabling the direct application of existing methods to new discoveries while also inspiring researchers to approach their screening projects in a conceptually modular fashion, enhancing the power to discover through new combinations of existing approaches.
High Throughput Screening
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Author : William P. Janzen
language : en
Publisher: Humana Press
Release Date : 2002-04-18
High Throughput Screening written by William P. Janzen and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-18 with Medical categories.
In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
High Throughput Screening In Drug Discovery
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Author : Jörg Hüser
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13
High Throughput Screening In Drug Discovery written by Jörg Hüser and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results. For both academics and professionals in the pharma and biotech industries working on small molecule screening.
Preclinical Drug Discovery
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Author : Sheraz Gul
language : en
Publisher:
Release Date : 2012-10
Preclinical Drug Discovery written by Sheraz Gul and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10 with categories.
These books provide theoretical, practical and troubleshooting guidelines on various aspects of the pre-clinical drug discovery process.
Preclinical Drug Discovery
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Author : Sheraz Gul
language : en
Publisher: RSC Drug Discovery
Release Date : 2014-01-31
Preclinical Drug Discovery written by Sheraz Gul and has been published by RSC Drug Discovery this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-31 with Medical categories.
This book is one of a three-volume set that provides theoretical, practical and troubleshooting guidelines on all aspects of the pre-clinical Drug Discovery process. There is particular focus on the design, development and role of screening assays in Drug Discovery, including new developments and future trends, the main assay types utilized in screening campaigns, and the methods utilized in enabling the progression of "Hits" to "Leads" and "Candidates" The books will fill current gaps in the literature such as primary, stem cell and other novel assay methods. Other relatively new research areas included are siRNA, high content screening, protein-protein interactions, pathway assays, non micro-titre plate based assays, label free assays, IT tools, approaches to identify biopharmaceuticals, emerging models and future trends in Drug Discovery.
High Throughput Screening
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Author : William P. Janzen
language : en
Publisher: Methods in Molecular Biology
Release Date : 2009-07-09
High Throughput Screening written by William P. Janzen and has been published by Methods in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-09 with Juvenile Nonfiction categories.
Featuring new screening technologies as well as many well established methods, this book offers comprehensive treatment of the activities directly related to High Throughput Screening (HTS), such as compound library management, data handling, and robotics.
A Practical Guide To Assay Development And High Throughput Screening In Drug Discovery
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Author : Taosheng Chen
language : en
Publisher: CRC Press
Release Date : 2009-12-21
A Practical Guide To Assay Development And High Throughput Screening In Drug Discovery written by Taosheng Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-21 with Medical categories.
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A P
Drug Discovery And Development
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Author : Omboon Vallisuta
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-06-03
Drug Discovery And Development written by Omboon Vallisuta and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-03 with Medical categories.
It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.
3d Cell Based Biosensors In Drug Discovery Programs
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Author : William S. Kisaalita
language : en
Publisher: CRC Press
Release Date : 2010-06-22
3d Cell Based Biosensors In Drug Discovery Programs written by William S. Kisaalita and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of the foremost experts in this field, 3D Cell-Based Bio
Preclinical Drug Discovery
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Author : Royal Society of Chemistry
language : en
Publisher:
Release Date : 2014-01-31
Preclinical Drug Discovery written by Royal Society of Chemistry and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-31 with Science categories.
This book is one of a three-volume set that provides theoretical, practical and troubleshooting guidelines on all aspects of the pre-clinical Drug Discovery process. There is particular focus on the design, development and role of screening assays in Drug Discovery, including new developments and future trends, the main assay types utilized in screening campaigns, and the methods utilized in enabling the progression of ""Hits"" to ""Leads"" and ""Candidates"" The books will also fill current gaps in the literature such as primary, stem cell and other novel assay methods. Other relatively new research areas included are siRNA, high content screening, protein-protein interactions, pathway assays, non micro-titre plate based assays, label free assays, IT tools, approaches to identify biopharmaceuticals, emerging models and future trends in Drug Discovery.