Optimal Impulsive Control For Cancer Therapy
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Optimal Impulsive Control For Cancer Therapy
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Author : João P. Belfo
language : en
Publisher: Springer Nature
Release Date : 2020-06-19
Optimal Impulsive Control For Cancer Therapy written by João P. Belfo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-19 with Technology & Engineering categories.
This Springer brief discusses the use of control engineering methods to plan a cancer therapy which tends to reduce tumour size in patients, striking a balance that minimizes the toxic effects of the treatment. The authors address the design and computation of impulsive control therapies, a methodology previously underexplored in the application of control methods to medical modelling. This allows simulation of such discrete events as taking a pill rather than relying on the supply of therapy being continuous and steady. The book begins with an introduction to the topic, before moving onto pharmacokinetic, pharmacodynamical and tumour-growth models and explaining how they describe the relationship between a certain therapy plan and the evolution of cancer. This is placed firmly in the context of work introducing impulsive differential equations. The final chapter summarizes the research presented and suggests future areas of research to encourage readers in taking the subject forward. This book is of interest to biomedical engineers, researchers and students, particularly those with a background in systems and control engineering.
Complex Systems Spanning Control And Computational Cybernetics Applications
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Author : Peng Shi
language : en
Publisher: Springer Nature
Release Date : 2022-09-18
Complex Systems Spanning Control And Computational Cybernetics Applications written by Peng Shi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-18 with Technology & Engineering categories.
This book, dedicated to Professor Georgi M. Dimirovski on his anniversary, contains new research directions, challenges, and many relevant applications related to many aspects within the broadly perceived areas of systems and control, including signal analysis and intelligent systems. The project comprises two volumes with papers written by well known and very active researchers and practitioners. The first volume is focused on more foundational aspects related to general issues in systems science and mathematical systems, various problems in control and automation, and the use of computational and artificial intelligence in the context of systems modeling and control. The second volume is concerned with a presentation of relevant applications, notably in robotics, computer networks, telecommunication, fault detection/diagnosis, as well as in biology and medicine, and economic, financial, and social systems too.
Advances In Nonlinear Dynamics
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Author : Walter Lacarbonara
language : en
Publisher: Springer Nature
Release Date : 2022-03-01
Advances In Nonlinear Dynamics written by Walter Lacarbonara and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-01 with Technology & Engineering categories.
This third of three volumes includes papers from the second series of NODYCON, which was held virtually in February of 2021. The conference papers reflect a broad coverage of topics in nonlinear dynamics, ranging from traditional topics from established streams of research to those from relatively unexplored and emerging venues of research. These include · Complex dynamics of COVID-19: modeling, prediction and control · Nonlinear phenomena in bio-systems and eco-systems · Energy harvesting · MEMS/NEMS · Multifunctional structures, materials and metamaterials · Nonlinear waves · Chaotic systems, stochasticity, and uncertainty
Automated Drug Delivery In Anesthesia
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Author : Dana Copot
language : en
Publisher: Academic Press
Release Date : 2020-04-29
Automated Drug Delivery In Anesthesia written by Dana Copot and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-29 with Science categories.
Automated Drug Delivery in Anesthesia provides a full review of available tools and methods on the drug delivery of anesthesia, bridging the gap between academic development, research and clinical practice. The book takes an interdisciplinary approach, pulling information about tools developed in other disciplines such as mathematics, physics, biology and system engineering and applying them to drug delivery. The book's authors discuss the missing element of complete regulatory loop of anesthesia: the sensor and model for pain pathway assessment. This is the only book which focuses specifically on the delivery of anesthesia. Revisits the standard TCI anesthesia regulatory loop Provides complementary measurement devices and protocols for hypnosis, analgesia and neuromuscular blockade (the three components for anesthesia) Describes the link between existing and emerging tools
Optimal Control For Mathematical Models Of Cancer Therapies
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Author : Heinz Schättler
language : en
Publisher: Springer
Release Date : 2015-09-15
Optimal Control For Mathematical Models Of Cancer Therapies written by Heinz Schättler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-15 with Mathematics categories.
This book presents applications of geometric optimal control to real life biomedical problems with an emphasis on cancer treatments. A number of mathematical models for both classical and novel cancer treatments are presented as optimal control problems with the goal of constructing optimal protocols. The power of geometric methods is illustrated with fully worked out complete global solutions to these mathematically challenging problems. Elaborate constructions of optimal controls and corresponding system responses provide great examples of applications of the tools of geometric optimal control and the outcomes aid the design of simpler, practically realizable suboptimal protocols. The book blends mathematical rigor with practically important topics in an easily readable tutorial style. Graduate students and researchers in science and engineering, particularly biomathematics and more mathematical aspects of biomedical engineering, would find this book particularly useful.
The Landscape Of Global Health Inequity
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Author : Barbara W. K. Son
language : en
Publisher: Springer Nature
Release Date :
The Landscape Of Global Health Inequity written by Barbara W. K. Son and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Modeling And Control Of Infectious Diseases In The Host
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Author : Esteban A. Hernandez-Vargas
language : en
Publisher: Academic Press
Release Date : 2019-02-15
Modeling And Control Of Infectious Diseases In The Host written by Esteban A. Hernandez-Vargas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-15 with Technology & Engineering categories.
Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments
Optimal Control Of Dynamic Systems Driven By Vector Measures
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Author : N. U. Ahmed
language : en
Publisher: Springer Nature
Release Date : 2021-09-13
Optimal Control Of Dynamic Systems Driven By Vector Measures written by N. U. Ahmed and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-13 with Mathematics categories.
This book is devoted to the development of optimal control theory for finite dimensional systems governed by deterministic and stochastic differential equations driven by vector measures. The book deals with a broad class of controls, including regular controls (vector-valued measurable functions), relaxed controls (measure-valued functions) and controls determined by vector measures, where both fully and partially observed control problems are considered. In the past few decades, there have been remarkable advances in the field of systems and control theory thanks to the unprecedented interaction between mathematics and the physical and engineering sciences. Recently, optimal control theory for dynamic systems driven by vector measures has attracted increasing interest. This book presents this theory for dynamic systems governed by both ordinary and stochastic differential equations, including extensive results on the existence of optimal controls and necessary conditions for optimality. Computational algorithms are developed based on the optimality conditions, with numerical results presented to demonstrate the applicability of the theoretical results developed in the book. This book will be of interest to researchers in optimal control or applied functional analysis interested in applications of vector measures to control theory, stochastic systems driven by vector measures, and related topics. In particular, this self-contained account can be a starting point for further advances in the theory and applications of dynamic systems driven and controlled by vector measures.
Impulsive Control In Continuous And Discrete Continuous Systems
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Author : Boris M. Miller
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Impulsive Control In Continuous And Discrete Continuous Systems written by Boris M. Miller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Mathematics categories.
Impulsive Control in Continuous and Discrete-Continuous Systems is an up-to-date introduction to the theory of impulsive control in nonlinear systems. This is a new branch of the Optimal Control Theory, which is tightly connected to the Theory of Hybrid Systems. The text introduces the reader to the interesting area of optimal control problems with discontinuous solutions, discussing the application of a new and effective method of discontinuous time-transformation. With a large number of examples, illustrations, and applied problems arising in the area of observation control, this book is excellent as a textbook or reference for a senior or graduate-level course on the subject, as well as a reference for researchers in related fields.
The New Frontier Of Network Physiology From Temporal Dynamics To The Synchronization And Principles Of Integration In Networks Of Physiological Systems
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Author : Plamen Ch. Ivanov
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-17
The New Frontier Of Network Physiology From Temporal Dynamics To The Synchronization And Principles Of Integration In Networks Of Physiological Systems written by Plamen Ch. Ivanov and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-17 with Science categories.