Organization And Evolution Of Chromosome Specific Human Alpha Satellite Dna
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Organization And Evolution Of Chromosome Specific Human Alpha Satellite Dna
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Author : John Stewart Waye
language : en
Publisher:
Release Date : 1987
Organization And Evolution Of Chromosome Specific Human Alpha Satellite Dna written by John Stewart Waye and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
Repetitive Dna
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Author : Manuel A. Garrido-Ramos
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2012
Repetitive Dna written by Manuel A. Garrido-Ramos and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the impact on genome structure, function and evolution. This publication is targeted at scientists and scholars at every level, from students to faculty members, and, indeed, anyone involved or interested in genetics, molecular evolution, molecular biology as well as genomics will find it a valuable source of up-to-date information.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
The Centromere
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Author : K. H. Andy Choo
language : en
Publisher: Oxford University Press, USA
Release Date : 1997
The Centromere written by K. H. Andy Choo and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Centromere categories.
The centromere is an essential structure on all eukaryotic chromosomes that allows the equipartition of chromosomes during mitotic and meiotic cell divisions. Since its cytogenetic recognition as a constructed part of a chromosome many decades ago, great advances have been made in ourunderstanding of this intriguing structure, especially at the molecular level. This book brings together all available information on the centromere. It covers in details the DNA and protein components of this structure, and their individual functions, in species as diverse as budding and fissionyeasts, nematodes, Drosophila, mice, and humans; newly discovered roles of the centromere in marshalling "passenger" proteins; important emerging concepts such as latent centromeres and epigenetic factors; cytogenetic problems associated with centromere abnormalities; and practical application ofcentromere studies, such as in the construction of human artificial chromosomes for gene therapy. Supported by ample illustrations, the book is written with sufficient simplicity and detail to suit both specialist and non-specialist scholars. It is the first book on the subject
The Major Transitions In Evolution
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Author : John Maynard Smith
language : en
Publisher: Oxford University Press
Release Date : 1997-10-30
The Major Transitions In Evolution written by John Maynard Smith and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-30 with Nature categories.
During evolution there have been several major changes in the way genetic information is organized and transmitted from one generation to the next. These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance of multicellular plants and animals, the emergence of cooperation and of animal societies. This is the first book to discuss all these major transitions and their implications for our understanding of evolution.Clearly written and illustrated with many original diagrams, this book will be welcomed by students and researchers in the fields of evolutionary biology, ecology, and genetics.
The Neutral Theory Of Molecular Evolution
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Author : Motoo Kimura
language : en
Publisher: Cambridge University Press
Release Date : 1983
The Neutral Theory Of Molecular Evolution written by Motoo Kimura and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
This book is the first comprehensive treatment of this subject.
Centromeres And Kinetochores
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Author : Ben E. Black
language : en
Publisher: Springer
Release Date : 2017-08-23
Centromeres And Kinetochores written by Ben E. Black and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Science categories.
This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring. The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as well as those already acquainted with the field.
Centromere
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Author : Durdica Ugarkovic
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-12
Centromere written by Durdica Ugarkovic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-12 with Science categories.
The centromere is a chromosomal region that enables the accurate segregation of chromosomes during mitosis and meiosis. It holds sister chromatids together, and through its centromere DNA–protein complex known as the kinetochore binds spindle microtubules to bring about accurate chromosome movements. Despite this conserved function, centromeres exhibit dramatic difference in structure, size, and complexity. Extensive studies on centromeric DNA revealed its rapid evolution resulting often in significant difference even among closely related species. Such a plasticity of centromeric DNA could be explained by epigenetic c- trol of centromere function, which does not depend absolutely on primary DNA sequence. According to epigenetic centromere concept, which is thoroughly d- cussed by Tanya Panchenko and Ben Black in Chap. 1 of this book, centromere activation or inactivation might be caused by modifications of chromatin. Such acquired chromatin epigenetic modifications are then inherited from one cell di- sion to the next. Concerning centromere-specific chromatin modification, it is now evident that all centromeres contain a centromere specific histone H3 variant, CenH3, which replaces histone H3 in centromeric nucleosomes and provides a structural basis that epigenetically defines centromere and differentiates it from the surrounding chromatin. Recent insights into the CenH3 presented in this chapter add important mechanistic understanding of how centromere identity is initially established and subsequently maintained in every cell cycle.
Atlas Of Human Chromosome Heteromorphisms
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Author : H.E. Wyandt
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Atlas Of Human Chromosome Heteromorphisms written by H.E. Wyandt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not. That distinction is often challenging and not infrequently requires considerable experience at the bedside. It is not surprising that accurate cytogenetic diagnosis is also often a challenge, especially when chromosome study reveals morphologic findings that raise the question of normality. Given the realization that modern human cytogenetics is just over five decades old, it is noteworthy that thorough documentation of normal chromosome var- tion has not yet been accomplished. One key diagnostic consequence of the inability to distinguish a “normal” variation in chromosome structure from a pathologic change is a missed or inaccurate diagnosis. Clinical cytogeneticists have not, however, been idle. Rather, progressive biotechnological advances coupled with virtual completion of the human genome project have yielded increasingly better microscopic resolution of chromosome structure. Witness the progress from the early short condensed chromosomes to the later visualization of chromosomes through banding techniques, hi- resolution analysis in prophase, and more recently to analysis by fluorescent in situ hybridization (FISH).
Human Chromosome Variation Heteromorphism And Polymorphism
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Author : Herman E. Wyandt
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-08-20
Human Chromosome Variation Heteromorphism And Polymorphism written by Herman E. Wyandt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-20 with Medical categories.
Human Chromosome Variation: Heteromorphism and Polymorphism was formerly printed under the title “Atlas of Human Chromosome Heteromorphism”. The Atlas has become a standard reference book in most cytogenetic laboratories and is cited as a significant reference in ISCN 2009. This revised version has updated and retained the most useful pictorial sections of the first edition, including the comprehensive review of normal and “not-so-normal” variations of the human karyotype with summaries and extensive reference lists organized by chromosome number. This updated edition features concise background information on chromosome methods and applications, essential information on heteromorphism frequencies in normal and clinical populations as well as new listing and discussions of euchromatic, subtelomeric and FISH variants. The addition of two new sections make this an even more valuable reference than before. A section on common and rare fragile sites includes a short historical discussion, definitions and an extensive table of officially recognized sites that includes the HUGO name, chromosomal location, methods of induction, genes and references to the most recent molecular characterization. A new section on array CGH discusses the clinical challenge of interpreting copy number variations (CNVs) revealed by this newest technology, gives examples of various levels of interpretation and lists the several most common websites used in this interpretation.