Overproduction And Utilization Of Enzymes In Synthetic Organic Chemistry
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Enzymes In Synthetic Organic Chemistry
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Author : Wong
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Enzymes In Synthetic Organic Chemistry written by Wong and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
This book covers the most recent development of enzymatic organic synthesis, with particular focus on the use of isolated enzymes. It is organized into one introductory chapter dealing with the characteristics of enzymes as catalysts, and five chapters dealing with different types of chemical transformations. Methods for enzyme immobilization and stabilizaton, the use of enzymes in extreme environments, and the alteration of enzyme properties by chemical modification and site-directed mutagenesis for synthetic purposes are covered.
Enzymes In Action Green Solutions For Chemical Problems
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Author : B. Zwanenburg
language : en
Publisher: Springer Science & Business Media
Release Date : 2000
Enzymes In Action Green Solutions For Chemical Problems written by B. Zwanenburg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Science categories.
Enzymes in Action is a timely survey of a modern development in organic chemistry. It is clear that bioreagents demand that organic chemists think in a different way. If they do so, they will open up new avenues of exciting, new chemistry that will permit problems to be solved in an elegant way. The first section covers the concepts necessary to understand enzymes in molecular operations. The second section covers heteroatom enzyme chemistry, with considerable attention being given to the use of enzymes in the detoxification of chemical warfare agents and their application in environmental problems. The final section highlights the strategic use of enzymes in organic chemistry. It is clear that the term 'green chemistry' is appropriate, since enzyme mediated processes occur under mild, environmentally benign conditions, and enzymes enable chemists to perform new chemical operations that would otherwise be difficult to achieve at all.
Faculties Publications And Doctoral Theses In Chemistry And Chemical Engineering At United States Universities
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Author : American Chemical Society. Committee on Professional Training
language : en
Publisher:
Release Date : 1991
Faculties Publications And Doctoral Theses In Chemistry And Chemical Engineering At United States Universities written by American Chemical Society. Committee on Professional Training and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Chemical engineering categories.
Enzymes In Carbohydrate Synthesis
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Author : Mark D. Bednarski
language : en
Publisher:
Release Date : 1991
Enzymes In Carbohydrate Synthesis written by Mark D. Bednarski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Not only assessing the past, present, and future uses of enzymes to synthesize carbohydrates, this volume also illustrates the significance of carbohydrate chemistry and describes how the combination and use of modern enzyme chemistry can advance exploration in the field. Details research at the interface of chemistry and biology for carbohydrate chemistry by demonstrating how to integrate chemical reactions and biological techniques that can be used to synthesize complex bioactive monosaccharides, oligosaccarides, and glycoconjugates. Of particular interest are chapters by George Whitesides and Chi-Huey Wong covering the use of enzymes in monosaccharide synthesis, and Hindsgaul, Thiem, Nilsson, and Whitesides describing the use of activated sugar nucleosides and glycosyltransferases in the synthesis of oligosaccharides and polysaccharides.
Biocatalysis In The Pharmaceutical And Biotechnology Industries
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Author : Ramesh N. Patel
language : en
Publisher: CRC Press
Release Date : 2006-09-26
Biocatalysis In The Pharmaceutical And Biotechnology Industries written by Ramesh N. Patel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-26 with Science categories.
Because enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity, substrate specificity, and stability, they require mild conditions to react while prompting higher reaction efficiency and product yields. Biocatalysis in the Pharmaceutical and Biotechnology Industries examines the use of catalysts to produce fine chemicals and chiral intermediates in a variety of pharmaceutical, agrochemical, and other biotechnological applications. Written by internationally recognized scientists in biocatalysis, the authors analyze the synthesis of chiral intermediates for over 60 brand-name pharmaceuticals for a wide range of drug therapies and treatments. From starting material to product, the chapters offer detailed mechanisms that show chiral intermediates and other by-products for each reaction—including hydrolytic, acylation, halogenation, esterification, dehalogenation, oxidation-reduction, oxygenation, hydroxylation, deamination, transamination, and C–C, C–N, C–O bonds formation. Cutting-edge topics include advanced methodologies for gene shuffling and directed evolution of biocatalysts; the custom engineering of enzymes; the use of microbial cells and isolated biocatalysts; the use of renewable starting materials; and generating novel molecules by combinatorial biocatalysis and high-throughput screening. Focusing on industrial applications, the book also considers factors such as bulk processes, instrumentation, solvent selection, and techniques for catalyst immobilization, reusability, and yield optimization throughout. Biocatalysis in the Pharmaceutical and Biotechnology Industries showcases the practical advantages and methodologies for using biocatalysts to develop and produce chiral pharmaceuticals and fine chemicals.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2004
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Dissertations, Academic categories.
The Organic Chemistry Of Drug Design And Drug Action
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Author : Richard B. Silverman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Organic Chemistry Of Drug Design And Drug Action written by Richard B. Silverman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization
American Doctoral Dissertations
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Author :
language : en
Publisher:
Release Date : 1989
American Doctoral Dissertations written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Dissertation abstracts categories.
Glycopeptides And Related Compounds
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Author : David G. Large
language : en
Publisher: CRC Press
Release Date : 1997-05-06
Glycopeptides And Related Compounds written by David G. Large and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-06 with Medical categories.
"Presents state-of-the-art methods for the synthesis, analysis, and conformational investigation of glycoproteins and glycopeptides. Discusses the history of glycopeptide synthesis, therapeutic applications, and the future of research."
Preparative Carbohydrate Chemistry
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Author : Stephen Hanessian
language : en
Publisher: CRC Press
Release Date : 1997-01-02
Preparative Carbohydrate Chemistry written by Stephen Hanessian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-02 with Science categories.
Detailing commonly used methods and procedures, this reference discusses the reactions and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the formation, cleavage, and reactions of derivatives and illustrates bond-forming reactions of SN2 types, free radicals, chain extensions, and branching. The contents include: sugar derivatives; selected reactions in carbohydrate chemistry; chemical synthesis of oligosaccharides and O-and N -glycosyl compounds; enzymatic synthesis of sialic acid, KDO, and related deoxyulosonic acids, and of oligosaccharides; synthesis of -glycosyl compounds; carbocycles from carbohydrates; and total synthesis of sugars from non-sugars. This authoritative reference offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. It also contains insightful chapter commentaries and succinct topic histories.