Oxidation And Reduction Processes In Vivo And In Vitro
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Oxidation And Reduction Processes In Vivo And In Vitro
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Author : Yan Kazakov
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2024-02-29
Oxidation And Reduction Processes In Vivo And In Vitro written by Yan Kazakov and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-29 with Medical categories.
This book introduces a novel approach to comprehending and assessing oxidative stress and antioxidant activity as fundamental components in both health and disease. It explores the advantages and peculiarities of innovative electrochemical methods for estimating and monitoring these processes. Recognizing the electrochemical nature of oxidative stress, the book advocates for electrochemical methods as the preferred means of determination. A central focus of the book is the presentation of a new electrochemical method for evaluating oxidative stress and antioxidant activity: potentiometric determination. The book presents results of antioxidant activity analyses for both healthy individuals and patients with diverse pathologies. Additionally, the book discusses the prospective advantages of employing potentiometry as a monitoring tool in areas such as diet, sports, and wellness. Further considerations extend to the future applications of oxidative stress monitoring, encompassing wearable devices, sensors, non-invasive assessments, and telemedicine. In short, this book establishes the method's credibility as a diagnostic criterion for studying oxidative stress across laboratory settings, bedside applications, and everyday life.
Free Radicals In Biology V4
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V4 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and the chemistry of the enzyme glutathione peroxidase. The next chapter is devoted to the kinetic aspects of lipid peroxidation and the multiple ways in which autoxidants can react. The reader is then introduced to the mechanisms of hepatoxicity by synthetic chemicals present in the environment, together with direct mechanisms of radiation damage to nucleic acids. Subsequent chapters deal with spin trapping in biological systems; the role of free radicals in arylamine carcinogenesis and their influence on the structure and reactivity of melanins; and the involvement of vitamin ? and lipid antioxidants in free-radical-initiated reactions. This book will be of value to chemists, biologists, and physicians.
Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1988
Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Cancer categories.
Logic In Reality
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Author : JOSEPH BRENNER
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-20
Logic In Reality written by JOSEPH BRENNER and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-20 with Philosophy categories.
This book is both dif?cult and rewarding, affording a new perspective on logic and reality, basically seen in terms of change and stability, being and becoming. Most importantly it exemplifies a mode of doing philosophy of science that seems a welcome departure from the traditional focus on purely analytic arguments. The author approaches ontology, metaphysics, and logic as having offered a number of ways of constructing the description of reality, and aims at deepening their relationships in a new way. Going beyond the mere abstract and formal aspects of logical analysis, he offers a new architecture of logic that sees it as applied not only to the “reasoning processes” belonging to the first disciplinary group – ontology – but also directly concerned with en- ties, events, and phenomena studied by the second one – metaphysics. It is the task of the book to elaborate such a constructive logic, both by offering a lo- cal view of the structure of the reality in general and by proffering a wealth of models able to encompass its implications for science. In turning from the merely formal to the constructive account of logic Brenner overcomes the limitation of logic to linguistic concepts so that it can be not only a logic “of” reality but also “in” that reality which is constitutively characterized by a number of fundamental dualities (observer and observed, self and not-self, internal and external, etc.
Oxidative Folding Of Peptides And Proteins
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Author : Luis Moroder
language : en
Publisher: Royal Society of Chemistry
Release Date : 2009
Oxidative Folding Of Peptides And Proteins written by Luis Moroder and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.
With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.
Oxidants Antioxidants And Impact Of The Oxidative Status In Male Reproduction
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Author : Ralf Henkel
language : en
Publisher: Academic Press
Release Date : 2018-08-23
Oxidants Antioxidants And Impact Of The Oxidative Status In Male Reproduction written by Ralf Henkel and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-23 with Medical categories.
Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. - Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches - Deals with current approaches to oxidative stress using OMICS platform - Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Handbook Of Antioxidant Methodology
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Author : Paul D Prenzler
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-10-12
Handbook Of Antioxidant Methodology written by Paul D Prenzler and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-12 with Science categories.
The field of antioxidant research has grown rapidly over the last 30 years and shows no sign of slowing down. In order to understand how antioxidants work, it is essential to understand how their activity is measured. However, antioxidant activity measurements are controversial and their value has been challenged. This book addresses a number of the controversies on antioxidant testing methods. Specifically, the book highlights the importance of context, helping the reader to decide what methods are most appropriate for different situations, how the results can be interpreted and what information may be inferred from the data. There are a multiplicity of methods for measuring activity, with no standardized method approved for in vitro or in vivo testing. In order to select an appropriate method, a thorough knowledge of the processes associated with reduction-oxidation is essential, leading to an improved understanding and use of activity measurements and the associated data. The book presents background information, in a unique style, which is designed to assist readers to grasp the fundamentals of redox processes, as well as thermodynamics and kinetics, which are essential to later chapters. Recovery and extraction of antioxidants from diverse matrices are presented in a clear and logical fashion along with methods used to determine antioxidant activity from a mechanistic perspective. Other chapters present current methodologies used for activity testing in different sample types ranging from foods and plants, to body fluids and even to packaging, but always with a strong emphasis on the nature of the sample and the underlying chemistry of the method. A number of emerging techniques for assessing antioxidant behaviour, namely, electrochemical methods, chip technology exploiting microfluidic devices, metabolomics plus studies of gene and protein expression, are examined. Ultimately, these techniques will be involved in generation of "big data" for which an understanding of chemometrics will be essential in drawing valid conclusions. The book is written to appeal to a wide audience, but will be particularly helpful for any researchers who are attempting to make sense of the vast literature and often conflicting messages on antioxidant activity.
Innovations For Next Generation Antibody Drug Conjugates
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Author : Marc Damelin
language : en
Publisher: Springer
Release Date : 2018-05-29
Innovations For Next Generation Antibody Drug Conjugates written by Marc Damelin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-29 with Medical categories.
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
The Journal Of Mental Science
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Author :
language : en
Publisher:
Release Date : 1942
The Journal Of Mental Science written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1942 with Electronic journals categories.
Advances In Morphogenesis
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Author : M. Abercrombie
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Advances In Morphogenesis written by M. Abercrombie and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Advances in Morphogenesis, Volume 1 covers the significant advances in various aspects of morphogenesis. This book is composed of nine chapters that include discussion on cell growth, differentiation, and development. The opening chapter describes the complex process of embryonic organization, from the induction initiation to a number of differentiation processes, leading to formation of the essential part of the axial system of the embryo. The next chapters examine the basic aspects of embryology, the process of regeneration in vertebrate, the suppression of growth processes by morphostatic substances, and the role of proteases in tissue regeneration. These topics are followed by discussions on the factors that control plant cell growth and the morphological, physiological, and biochemical studies of normal pigment cell development and differentiation. The concluding chapters explore the development of limbs of tetrapod vertebrates, the morphogenesis of the vertebrate eye, and the particular phases of teleostean egg development. This book is directed toward developmental biologists.