Particulate Interactions In Dry Powder Formulation For Inhalation
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Particulate Interactions In Dry Powder Formulation For Inhalation
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Author : Xian Ming Zeng
language : en
Publisher: CRC Press
Release Date : 2000-10-26
Particulate Interactions In Dry Powder Formulation For Inhalation written by Xian Ming Zeng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-26 with Medical categories.
Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).
Particulate Interactions In Dry Powder Formulations For Inhalation
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Author : Xian Ming Zeng
language : en
Publisher:
Release Date : 2003
Particulate Interactions In Dry Powder Formulations For Inhalation written by Xian Ming Zeng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems
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Author : Ashok Katdare
language : en
Publisher: CRC Press
Release Date : 2006-07-28
Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems written by Ashok Katdare and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-28 with Medical categories.
To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.
Pulmonary Drug Delivery
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Author : Ali Nokhodchi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-06-01
Pulmonary Drug Delivery written by Ali Nokhodchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Science categories.
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.
Handbook Of Lung Targeted Drug Delivery Systems
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Author : Yashwant Pathak
language : en
Publisher: CRC Press
Release Date : 2021-10-17
Handbook Of Lung Targeted Drug Delivery Systems written by Yashwant Pathak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-17 with Medical categories.
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems
Dry Powder Inhalers
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Author : Teerapol Srichana
language : en
Publisher:
Release Date : 2017
Dry Powder Inhalers written by Teerapol Srichana and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Inhalers categories.
This book is a compilation of most works published during 2000-2016 in the area of dry powder inhalers, especially related to the issues with formulation and device design. The dry powder inhalers aim to deliver the medication to the respiratory airways. It is suitable for postgraduate students and researchers who work in the areas of dry powder inhalers. It provides some background knowledge in size characterization, flow properties, forces, and interaction of air and particles. It also ends with in vitro quality control of dry powder inhalers. This book was finished in Hawaii where the author spent his time during April 2016. Thank you to Prince of Songkla University for the financial support. The author had to work very hard for one month without a holiday. Thank you to Professor Aran Pattanothai for overseeing this work to make sure that the researchers were on schedule all the time. Thanks to the authors staff at the Graduate School, Prince of Songkla University who had to work hard and be patient when the author was not in the office. Thanks to the authors wife and son who had to wait for him at home in Thailand. Thanks to Dr Tan Suwandecha and Dr Janwit Dechraksa for their great efforts in copy editing and compiling all the references. The author also thanks Dr Somchai Sawatdee and Dr Dhamodharan Bakkiyaraj for their comments, and Dr Padmavathi Alwar Ramanujam for her proofreading. The greatest help was from Professor Alan Coombes, Professor Pornanong Aramwit, and Dr Brian Hodgeson for their criticisms and comments to make this book readable.
Drug Delivery To The Lung
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Author : Hans Bisgaard
language : en
Publisher: CRC Press
Release Date : 2001-10-02
Drug Delivery To The Lung written by Hans Bisgaard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-02 with Medical categories.
This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.
Fundamentals Of Drug Delivery
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Author : Heather A. E. Benson
language : en
Publisher: John Wiley & Sons
Release Date : 2021-09-30
Fundamentals Of Drug Delivery written by Heather A. E. Benson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-30 with Medical categories.
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Spray Freeze Drying Of Foods And Bioproducts
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Author : S. Padma Ishwarya
language : en
Publisher: CRC Press
Release Date : 2022-04-19
Spray Freeze Drying Of Foods And Bioproducts written by S. Padma Ishwarya and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Medical categories.
Spray-freeze-drying (SFD) is a synergistic drying technology that imbibes in it the merits of both spray drying and freeze-drying, whilst overcoming the limitations of these predecessor technologies. SFD produces uniquely powdered food and pharmaceutical products with porous microstructure and superior quality attributes. Owing to its atomization step and ultra-low-temperature operation, SFD is a competent drying technique for the production of valuable but sensitive bioactive components. Despite the costs and complexities involved, SFD has a competitive edge over the conventional drying techniques in providing distinctive product attributes. The applications of spray-freeze-drying in the area of food and bioproducts span across the product categories of instant food powders, dry flavors, active pharmaceutical ingredients, poorly water-soluble drugs, probiotics, proteins, enzymes and vaccines. Spray-Freeze-Drying of Foods and Bioproducts: Theory, Applications and Perspectives is the first exclusive title on this interesting drying technique. It provides a comprehensive understanding of the fundamentals of SFD and its food and pharmaceutical applications. The scope of this book, comprising 12 chapters, has been organizedunder four major headings: fundamentals of process-stages, applications with case-studies, recent advancements and the processing bottlenecks and solutions. Key Features Provides examples and case studies of nuances and intricacies associated with each stage of the spray-freeze-drying process Highlights the applications of spray-freeze-drying in the production of food products including soluble coffee, dairy powders, probiotics and flavors Serves as a ready-reckoner of characterization methods for spray-freeze-dried products Contains 200+ illustrations and tabulations The contents of this book are organized to cater to the knowledge needs of students, academicians, researchers and professionals in the food and pharmaceutical industry.
Pharmaceutical Inhalation Aerosol Technology Third Edition
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Author : Anthony J. Hickey
language : en
Publisher: CRC Press
Release Date : 2019-03-26
Pharmaceutical Inhalation Aerosol Technology Third Edition written by Anthony J. Hickey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-26 with Medical categories.
This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery. Key Features: Provides a thoroughly revised and expanded reference with authoritative discussions on the physiologic,pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosols Emphasizes the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery Addresses the physics, chemistry and engineering principles while establishing disease relevance Expands the ‘technology’ focus of the original volumes to address the title more directly Offers an impressive breadth of coverage as well as an international flavour from outstanding editors and contributors