Pathogenic Naegleria
DOWNLOAD
Download Pathogenic Naegleria PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Pathogenic Naegleria book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Pathogenic Naegleria
DOWNLOAD
Author : Flora Mae Wellings
language : en
Publisher:
Release Date : 1979
Pathogenic Naegleria written by Flora Mae Wellings and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Amoeba categories.
Brain Eating Amoebae
DOWNLOAD
Author : Ruqaiyyah Siddiqui
language : en
Publisher: Caister Academic Press Limited
Release Date : 2016
Brain Eating Amoebae written by Ruqaiyyah Siddiqui and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
Naegleria fowleri is a eukaryotic protist pathogen that causes primary amoebic meningoencephalitis. It is one of the world's deadliest known parasites with a mortality rate higher than 90%: infection almost always results in death. A greater scientific understanding of this parasite, how it lives in the environment and its pathogenic mechanism, is crucial for the development of preventative and therapeutic strategies against this fatal, albeit rare disease. This concise book on N. fowleri serves as a quick guide for clinical practitioners, health professionals, researchers and students working with this parasite. Divided into easy-to-follow sections, the book covers all aspects of research into N. fowleri as an organism ranging from clinical and laboratory diagnosis to growth and life cycle. It is essential reading for all microbiologists, immunologists, physicians, public health officials and researchers (both new and experienced) involved with N. fowleri. This book is an invaluable reference for everyone working in the field of basic and medical microbiology and a recommended acquisition for all parasitology, microbiology and medical libraries.
Studies On Pathogenic Naegleria Fowleri
DOWNLOAD
Author : Anthony L. Newsome
language : en
Publisher:
Release Date : 1982
Studies On Pathogenic Naegleria Fowleri written by Anthony L. Newsome and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Amoeba categories.
Pathogenic Naegleria
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1979
Pathogenic Naegleria written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Amoeba categories.
Pathogenic Naegleria
DOWNLOAD
Author : Flora Mae Wellings
language : en
Publisher:
Release Date : 1979
Pathogenic Naegleria written by Flora Mae Wellings and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Amoeba categories.
Isolation Of Pathogenic Naegleria From Artificially Heated Waters
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1977
Isolation Of Pathogenic Naegleria From Artificially Heated Waters written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.
Investigations were undertaken to determine whether heated waters facilitate the proliferation of free-living amoeba that cause primary amoebic meningoencephalitis. Water samples were taken close to the discharges of power plants situated on lakes or rivers in Florida and Texas and from cooling towers in Tennessee. The water temperatures ranged from 29 to 42°C. Water samples were also taken from several lakes in Florida and Texas without associated power plants. The water temperatures of these ranged from 30° to 34°C. Twenty-five-250-ml samples were filtered through membranes. Samples taken from the control lakes and cooling towers showed no growth of pathogenic amoeba, whereas growth was obtained from 2 of the 8 lakes and rivers in Florida and from 1 of the 7 man-made lakes in Texas that were artificially heated. The amoebae were identified as belonging to the genus Naegleria from their trophozoite and cyst structure, ability to grow at 45°C, to transform into flagellates, and to produce primary amebic meningoencephalitis (PAME) in mice after intranasal instillation. Their identification as N. fowleri was confirmed by indirect immunofluorescent analysis with antiserum produced against N. fowleri. These findings indicate that artificial heating of waters may facilitate the growth of pathogenic free living amoeba.
Free Living Amebas
DOWNLOAD
Author : A. Julio Martinez
language : en
Publisher: CRC Press
Release Date : 2019-08-08
Free Living Amebas written by A. Julio Martinez and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-08 with Science categories.
This book places greater emphasis on the practical problems of epidemiology, prevention, diagnosis, and pathological aspects of the two principle types of free-living amoebic infection: the acute disease produced by Naegleria fowleri and the chronic, subacute and opportunistic form, produced by acanthamoeba spp.
Identification Of Peptidases In Highly Pathogenic Versus Weakly Pathogenic Naegleria Fowleri Amebae
DOWNLOAD
Author : Ishan Kaushikkumar Vyas
language : en
Publisher:
Release Date : 2014
Identification Of Peptidases In Highly Pathogenic Versus Weakly Pathogenic Naegleria Fowleri Amebae written by Ishan Kaushikkumar Vyas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Naegleria fowleri, a free-living ameba, is the causative agent of Primary Amebic Meningoencephalitis. Highly-pathogenic mouse-passaged amebae (Mp) and weakly-pathogenic axenically-grown (Ax) N. fowleri were examined for peptidase activity. Zymography and azocasein peptidase activity assays demonstrated that Mp and Ax N. fowleri exhibited a similar peptidase pattern. Prominent for whole cell lysates, membranes and conditioned medium from Mp and Ax amebae were the presence of an activity band of approximately 58kDa and 100 kDa bands susceptible to the action of cysteine and metallopeptidase inhibitors, respectively. Further roles of the peptidases during the invasion process were examined by in vitro invasion assays in the presence of inhibitors and Cysteine and metallopeptidase inhibitors were found to greatly reduce invasion through the ECM. This study establishes a functional linkage of the expressed peptidases to the invasion process, and these peptidases may serve as a candidate target for therapeutic management of N. fowleri infection.
Pathogenic Naegleria Distribution In Nature
DOWNLOAD
Author : U. S. Environmental Protection Agency
language : en
Publisher: BiblioGov
Release Date : 2013-07
Pathogenic Naegleria Distribution In Nature written by U. S. Environmental Protection Agency and has been published by BiblioGov this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07 with categories.
The U.S. Environmental Protection Agency (EPA) was introduced on December 2, 1970 by President Richard Nixon. The agency is charged with protecting human health and the environment, by writing and enforcing regulations based on laws passed by Congress. The EPA's struggle to protect health and the environment is seen through each of its official publications. These publications outline new policies, detail problems with enforcing laws, document the need for new legislation, and describe new tactics to use to solve these issues. This collection of publications ranges from historic documents to reports released in the new millennium, and features works like: Bicycle for a Better Environment, Health Effects of Increasing Sulfur Oxides Emissions Draft, and Women and Environmental Health.
A Comparative Study Of A Pathogenic Versus A Nonpathogenic Naegleria Species
DOWNLOAD
Author : Melissa Jamerson
language : en
Publisher:
Release Date : 2011
A Comparative Study Of A Pathogenic Versus A Nonpathogenic Naegleria Species written by Melissa Jamerson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Naegleria fowleri (N. fowleri) and Naegleria lovaniensis (N. lovaniensis) are closely related amebae found in the environment. N. fowleri causes Primary Amebic Meningoencephalitis (PAM), a fatal disease of the central nervous system, while N. lovaniensis is nonpathogenic. N. fowleri infection occurs when amebae enter the nasal passages, and migrate to the brain. The molecular mechanisms involved in the pathogenesis of PAM are not well-defined. Therefore, the purpose of this study was to define phenotypic characteristics that may be functionally linked to the pathogenicity associated with N. fowleri. Studies revealed that N. fowleri has a faster growth rate and is more resistant to complement-mediated lysis when compared to N. lovaniensis. Additionally, contact-independent cytotoxicity was observed only for N. fowleri. The ability to invade tissues can be a characteristic that distinguishes pathogens from nonpathogens. Therefore, adhesion to extracellular matrix components (ECM), laminin-1, fibronectin, and collagen I, was assessed. N. fowleri exhibited a higher level of adhesion to ECM components and was shown to invade tri-dimensional ECM scaffolds (matrigel and collagen I) to a greater extent than N. lovaniensis. Scanning electron microscopy revealed that N. fowleri attached on ECM substrata exhibited a spread-out appearance that included the presence of focal adhesion-like structures. Attachment of N. fowleri to ECM components was decreased significantly when amebae were pretreated with trypsin, suggesting a role for a surface protein in this process. Pretreatment of N. fowleri amebae with periodate, a sugar oxidant, led to a decrease in attachment to laminin-1 and fibronectin suggesting that the surface component contained a sugar moiety. Western immunoblotting revealed two integrin-like proteins for both species. However, one with a molecular mass of approximately 70 kDa, was detected at a higher level for N. fowleri. Confocal microscopy indicated that the integrin-like proteins co-localized to the focal adhesion-like structures. An anti-integrin antibody decreased adhesion of N. fowleri to ECM components. Zymographic analysis demonstrated differential expression of proteases occurs when N. fowleri and N. lovaniensis invade ECM components using an in vitro invasion assay. These results indicate a distinction in adhesion to, and invasion of, extracellular matrix proteins between N. fowleri and N. lovaniensis.