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Pathophysiology Of The Enteric Nervous System


Pathophysiology Of The Enteric Nervous System
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The Enteric Nervous System


The Enteric Nervous System
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Author : John Barton Furness
language : en
Publisher:
Release Date : 1987

The Enteric Nervous System written by John Barton Furness and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.




Enteric Glia


Enteric Glia
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Author : Brian D. Gulbransen
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01

Enteric Glia written by Brian D. Gulbransen and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.


The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography



Pathophysiology Of The Enteric Nervous System


Pathophysiology Of The Enteric Nervous System
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Author : Robin Spiller
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Pathophysiology Of The Enteric Nervous System written by Robin Spiller and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.


Over the last few years there have been huge advances made in our understanding of the interactions between the brain and the gut – the enteric nervous system. This book is particularly relevant in the understanding, diagnosis and management of irritable bowel syndrome – the most common functional disorder of the bowel. IBS has been diagnosed in 10-20% of adults in the US, and symptoms of IBS are responsible for more than 3 million visits to the physician in the US. This book is aimed at specialist gastroenterologists but also should be of interest for trainees and fellows in gastroenterology, as well as PCPs and GPs with an interest in this subject.



The Brain


The Brain
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Author : Charles Watson
language : en
Publisher: Academic Press
Release Date : 2010

The Brain written by Charles Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. Based on contemporary neuroscience research rather than old-style medical school neuroanatomy Thorough treatment of motor and sensory systems A detailed chapter on human cerebral cortex The neuroscience of consciousness, memory, emotion, brain injury, and mental illness A comprehensive chapter on brain development A summary of the techniques of brain research A detailed glossary of neuroscience terms Illustrated with over 130 color photographs and diagrams This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine. Clearly and concisely written for easy comprehension by beginning students Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy Thorough treatment of motor and sensory systems A detailed chapter on human cerebral cortex Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness A comprehensive chapter on brain development A summary of the techniques of brain research A detailed glossary of neuroscience terms Illustrated with over 100 color photographs and diagrams



Colonic Motility


Colonic Motility
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Author : Sushil K. Sarna
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010

Colonic Motility written by Sushil K. Sarna and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood. Table of Contents: Introduction / Regulatory Mechanisms / Colonic Motility in Health / Colonic Motility Dysfunction / References



Structure Of Enteric Neurons


Structure Of Enteric Neurons
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Author : Axel Brehmer
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-10-06

Structure Of Enteric Neurons written by Axel Brehmer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-06 with Medical categories.


This book first presents an overview on the chemical coding of the morphological neuron types described by Stach in the pig intestine. In doing so, we have pointed out the difference between the definitions of type I neurons given by Dogiel and Stach. Secondly, it provides a basis for the morpho-chemical classification of human enteric neurons as revealed by their immunoreactivity for neurofilaments and several neuroactive substances or related markers.



Equine Acute Abdomen


Equine Acute Abdomen
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Author : Nathaniel A. White
language : en
Publisher: CRC Press
Release Date : 2009-10-31

Equine Acute Abdomen written by Nathaniel A. White and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-31 with Medical categories.


This title allows users to effectively diagnose and treat any acute disease of the stomach, intestines, peritoneum, liver, and abdominal wall. Its authorship includes over 20 internationally recognized experts that provide critical information needed by practitioners for management of abdominal diseases. This informative resource provides a thorough discussion of normal and abnormal anatomy and physiology. Surgical techniques are broken down into an easy-to-read step-by-step format. This highly visual presentation, with over 410 illustrations, is a necessary edition to an equine practitioner’s library. Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America.



Defining Physiology Principles Themes Concepts Volume 2


Defining Physiology Principles Themes Concepts Volume 2
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Author : Hwee Ming Cheng
language : en
Publisher: Springer
Release Date : 2021-01-25

Defining Physiology Principles Themes Concepts Volume 2 written by Hwee Ming Cheng and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-25 with Medical categories.


This second volume of Defining Physiology: Principles, Themes, Concepts. continues on the same format as the first. In this new release, a selection of 44 essential topics in each major organ system is defined, then major themes, concept and principles surrounding these words in their physiologic scenarios are elaborated. For each keyword, a question is posed at the end of the text to test for a better understanding of the associated physiology of nervous and gastrointestinal systems. This book presents an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.



Physiology Of The Gastrointestinal Tract


Physiology Of The Gastrointestinal Tract
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Author : Kim E. Barrett
language : en
Publisher: Elsevier
Release Date : 2006-05-10

Physiology Of The Gastrointestinal Tract written by Kim E. Barrett and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-10 with Medical categories.


FROM THE PREFACE:The original purpose of the First Edition of Physiology of the Gastrointestinal Tractto collect in one set of volumes the most current and comprehensive knowledge in our fieldwas also the driving force for the Fourth Edition. The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development, apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation, stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the "Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters were recruited and edited by Hamid M. Said and Fayez K. Ghishan.· Collected in one set - the most current and comprehensive coverage of gastrointestinal physiology· Information presented in a style that is both readable and understandable· Valuable to the specialized researcher, the clinical gastroenterologist, the teacher, and the student· Features an entirely new section on Immunology and Inflammation· Each section edited by the preeminent scientist in the field



Pathogenesis Of Functional Bowel Disease


Pathogenesis Of Functional Bowel Disease
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Author : William J. Snape Jr.
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Pathogenesis Of Functional Bowel Disease written by William J. Snape Jr. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


In their second year in medical school, students begin to learn about the differences between "disease" and "illness." In their studies of pathology they learn to understand disease as pertubations of molecular biological events. And we clinicians can show disease to them by our scans, lay it out even on our genetic scrolls, and sometimes even point out the errant nucleotide. Disease satisfies them and us; at Yale, lectures on the gastrointestinal tract run from achalasia to proctitis. There is, alas, little mention of functional bowel disease or of the irritable or spastic colon, for that is not easy to show on hard copy. Functional bowel disease represents "illness," the response of the person to distress, to food, to the environment, and to the existential problems of living. In real life such matters are most important. Richard Cabot first found out at the Massachusetts General Hospital almost a century ago that 50% of the patients attending the outpatient clinic had "functional" complaints. The figure had grown to over 80% when the very same question was reexamined 60 years later.