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Patterns Of Ischaemic Preconditioning On The Viability Of Rat Heart


Patterns Of Ischaemic Preconditioning On The Viability Of Rat Heart
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Patterns Of Ischaemic Preconditioning On The Viability Of Rat Heart


Patterns Of Ischaemic Preconditioning On The Viability Of Rat Heart
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Author : Katherine Jane Hewitt
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2012-04

Patterns Of Ischaemic Preconditioning On The Viability Of Rat Heart written by Katherine Jane Hewitt and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04 with categories.


Ischaemic preconditioning is a phenomenon where brief periods of ischaemia and reperfusion prior to a prolonged episode of ischaemia have a protective effect on tissue. Ischaemic preconditioning has been demonstrated in every animal species tested and many different tissues, including human myocardium (Yellon et al, 1993), (Hausenloy et al, 2007). Many different patterns of ischaemic preconditioning have been tested (Kloner and Jennings, 2001 a), and this investigation aimed to identify a pattern of ischaemic preconditioning that promoted protective effects in a rat heart strip model, with recovery of contractile function as end-point assessment. Three different patterns of ischaemia and reperfusion were tested and compared to a control group which received no preconditioning ischaemia. After preconditioning, all four groups were exposed to 30 minutes of ischaemia and 30 minutes reperfusion. Results showed some preconditioning effects in group 3 although statistical analysis found the results not to be significant. However, the pattern used in group 4 was found to exacerbate ischaemic damage, which was unexpected. Further testing is suggested.



Cumulated Index Medicus


Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.




Index Medicus


Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004

Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.


Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.



Ischaemia Reperfusion Injury


Ischaemia Reperfusion Injury
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Author : Pierce A. Grace
language : en
Publisher: Wiley-Blackwell
Release Date : 1999-02-04

Ischaemia Reperfusion Injury written by Pierce A. Grace and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-02-04 with Medical categories.


Ischaemia-Reperfusion Injury is concerned with the consequences of interrupting and restoring blood flow to tissues. Many common clinical conditions are caused by interruption of blood flow to tissues (eg, ischaemic heart disease, peripheral vascular disease, stroke); blood flow is also interrupted deliberately in many surgical procedures (eg, cardiac surgery, arterial surgery, transplant surgery, limb surgery with tourniquet). In treating such conditions or after performing such operations the aim of the clinician is to restore the blood supply to the ischaemic tissue. Paradoxically, restoration of blood flow to ischaemic tissues can lead to further tissue damage with the potential for severe local and systemic injury. This book focuses on the clinical, pathological and biochemical processes involved in ischaemia-reperfusion injury and gives an overview of the strategies that may be adopted to mitigate or prevent such injury. This book will be of interest to both clinicians and scientists who have to deal with or have interest in this difficult but important problem.



The Pathology Of Cardiac Transplantation


The Pathology Of Cardiac Transplantation
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Author : Ornella Leone
language : en
Publisher: Springer
Release Date : 2017-01-20

The Pathology Of Cardiac Transplantation written by Ornella Leone and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-20 with Medical categories.


This is the first book to focus entirely on the role of pathology in cardiac transplantation, linked to the clinical perspective through clinical–pathological correlation, multidisciplinary team working, and collaborative research. It provides a scientific framework with up-to-date pathological protocols and classification schemes and guides the reader through the chronological phases of the transplant process in a step-by-step approach. Topics include end-stage heart failure with pathologies encountered in the native heart, current issues surrounding donor selection, the multiple faces of rejection pathology correlated with clinical management and immunology, other post-transplant complications, details of pediatric and combined heart/other organ transplantation, and a useful practical appendix. Many high-quality images and illustrative cases are presented, along with learning points and ample references. Transplantation medicine today is continuously changing as collaborative research into novel diagnostic techniques and immunosuppressive therapies translates into improved recipient management and survival. This book is aimed at practicing transplant pathologists and specialist trainees. It will also appeal to general pathologists and to physicians and surgeons involved in cardiac transplantation who need to understand the role of pathology in the clinical management of transplant recipients.



Vascular Liver Disease


Vascular Liver Disease
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Author : Laurie D. DeLeve
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-23

Vascular Liver Disease written by Laurie D. DeLeve and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-23 with Medical categories.


Vascular Liver Disease: Mechanisms and Management covers all of the disease entities that stem from abnormalities that affect the hepatic vasculature. This multi-authored text includes the mechanisms and management of intrahepatic vascular disease, including the most common cause of vascular disease of the liver, cirrhosis. Other less common diseases of the liver vasculature are also covered such as sinusoidal obstruction syndrome (previously known as veno-occlusive disease), portal vein thrombosis, the Budd-Chiari syndrome and congenital vascular malformations. These entities, although rare, are a challenge to physicians and physician scientists. Although many textbooks have been written on the consequences of cirrhosis on the liver vasculature, this is the only volume that focuses on the liver vasculature as a separate entity, providing an innovative approach to liver disease management. Vascular Liver Disease: Mechanisms and Management will be of great value to clinical investigators and basic scientists interested in the liver circulation as well as clinical gastroenterologists and hepatologists, hepatobiliary surgeons and transplant surgeons, and to interventional radiologists with a particular interest in the liver.



Myocardial Protection


Myocardial Protection
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Author : Tomas A. Salerno
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Myocardial Protection written by Tomas A. Salerno and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.


Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.



Nitric Oxide And The Cardiovascular System


Nitric Oxide And The Cardiovascular System
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Author : Joseph Loscalzo
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-03-29

Nitric Oxide And The Cardiovascular System written by Joseph Loscalzo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-03-29 with Medical categories.


Leading clinical and experimental investigators comprehensively review the chemistry, biochemistry, molecular biology, physiology, and pathophysiology of nitric oxide in the cardiovascular systems. These experts particularly illuminate nitric oxide biology, its cardiovascular pathophysiology, and its role in cardiovascular therapeutics. Topics also included are the development of nitric oxide donors for the treatment of myocardial ischemia and thrombosis, the development of gene therapeutic restoration of endothelial function in atherosclerosis, and the application of nitric oxide biology to investigative arenas in cardiovascular medicine. With its balanced presentation of basic and clinically relevant information, Nitric Oxide and the Cardiovascular System provides a comprehensive, authoritative guide for all those cardiovascular biologists, cardiologists, physiologists, and cardiovascular surgeons engaged in today's clinical or experimental research.



Scott Brown S Otorhinolaryngology And Head And Neck Surgery


Scott Brown S Otorhinolaryngology And Head And Neck Surgery
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Author : John C Watkinson
language : en
Publisher: CRC Press
Release Date : 2018-06-12

Scott Brown S Otorhinolaryngology And Head And Neck Surgery written by John C Watkinson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-12 with Medical categories.


Available as a single volume and as part of the three volume set, Volume One of Scott-Brown's Otorhinolaryngology, Head and Neck Surgery 8e covers Basic Sciences, Endocrine Surgery, and Rhinology. With over 100 chapters and complemented by clear illustrations, the content focuses on evidence-based practice. Clinical coverage is further enhanced by a clear well designed colour page format to ensure easy learning and the esy assimilation of the most up to date material. Definitive coverage in a single volume, with e-version access included.



Heat Shock Proteins And Cytoprotection


Heat Shock Proteins And Cytoprotection
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Author : Alexander E. Kabakov
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Heat Shock Proteins And Cytoprotection written by Alexander E. Kabakov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.