Pediatric Cancer Genetics


Pediatric Cancer Genetics
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Pediatric Cancer Genetics


Pediatric Cancer Genetics
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Author : Nathaniel H. Robin
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-08-22

Pediatric Cancer Genetics written by Nathaniel H. Robin and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-22 with Medical categories.


Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.



Recent Advances In Pediatric Cancer Predisposition Syndromes


Recent Advances In Pediatric Cancer Predisposition Syndromes
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Author : Angela Mastronuzzi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-03

Recent Advances In Pediatric Cancer Predisposition Syndromes written by Angela Mastronuzzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-03 with Medical categories.


We would like to acknowledge Dr. Giada Del Baldo and Dr. Mariachiara Lodi from IRCCS Bambino Gesù Children’s Hospital have acted as coordinator and have contributed to the preparation of the proposal for this Research Topic.



The Hereditary Basis Of Childhood Cancer


The Hereditary Basis Of Childhood Cancer
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Author : David Malkin
language : en
Publisher: Springer Nature
Release Date : 2021-09-06

The Hereditary Basis Of Childhood Cancer written by David Malkin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-06 with Medical categories.


This volume elaborates on the research and clinical implications of the hereditary and molecular basis of childhood cancers. The focus of the ‘disease-related’ chapters of the book is to integrate what is known about the molecular basis of that particular clinical entity (or group of related entities) with the clinical manifestations, to relate the relationship of the molecular oncologic pathways with relevant developmental or non-human species biology in order to better understand the complexity of these systems. The resulting clinical implications of understanding this biology are elaborated on. Chapters 13-16 discuss the broader psychosocial, ethical and genetic counseling issues that arise and that are so critical to translating the knowledge gained from advances in molecular genetics into the clinic. Chapter 12 in particular provides a unique perspective of the application of this knowledge in less-developed nations where ‘modern’ technologies may not be readily available, but where the clinical manifestations of these disorders are prevalent.



Pediatric Hematology And Oncology


Pediatric Hematology And Oncology
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Author : Edward Estlin
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-20

Pediatric Hematology And Oncology written by Edward Estlin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-20 with Medical categories.


This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic approach to these disorders. This new textbook has an emphasis on the visual presentation and ease of reading of contemporary and comprehensive information for children’s cancers and contains detailed tables, fact boxes and illustrations. The textbook begins with an introduction to the general principles of the scientific foundation and treatment of childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of science covered, key original references and reviews are highlighted to direct further reading. Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies. A final section then explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children’s cancer.



Cancer Genetics


Cancer Genetics
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Author : Boris Pasche
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-02

Cancer Genetics written by Boris Pasche and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-02 with Medical categories.


Cancer Genetics is a collection of chapters covering the key recent developments in cancer genetics which have an impact on clinical care. The target audience will be physicians and scientists who need to be apprised on the most recent developments in the field.



Diagnostic And Therapeutic Advances In Pediatric Oncology


Diagnostic And Therapeutic Advances In Pediatric Oncology
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Author : David O. Walterhouse
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Diagnostic And Therapeutic Advances In Pediatric Oncology written by David O. Walterhouse and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.



Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Author : Kenneth Offit
language : en
Publisher: Clinics: Internal Medicine
Release Date : 2010

Genetic Predisposition To Cancer written by Kenneth Offit and has been published by Clinics: Internal Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition. Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.



Counseling About Cancer


Counseling About Cancer
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Author : Katherine A. Schneider
language : en
Publisher: John Wiley & Sons
Release Date : 2023-03-01

Counseling About Cancer written by Katherine A. Schneider and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-01 with Medical categories.


Counseling About Cancer A key resource for all genetic counselors and other healthcare providers, this comprehensive reference has been completely updated and reorganized for its fourth edition Over 50 hereditary cancer predisposition genes have now been identified. Genetic testing can be a powerful tool in assessing individual cancer risk and creating robust medical plans, but can also be a complex process, with personal and familial factors carrying real emotional weight. As such, genetic counseling for patients and their families during the process of genetic testing is critical. Counseling about Cancer: Strategies for Genetic Counseling is the only comprehensive resource available for clinicians who want to understand and apply these dimensions of patient care. This updated and reorganized edition provides detailed information designed to be incorporated in a variety of clinical and health-care contexts. Updated with the latest guidance and research, it promises to continue as the indispensable guide to this challenging subject. Readers of the fourth edition of Counseling about Cancer will also find: New chapters analyzing pediatric cancer syndromes, genetic testing technology, and more Increased focus on gynecological cancer syndromes and related genes Detailed case studies to reinforce themes of each chapter Counseling about Cancer is a useful reference for genetic counselors and other healthcare providers looking to familiarize themselves with best practices of patient counseling and care.



Molecular Diagnostics Of Pediatric Cancer


Molecular Diagnostics Of Pediatric Cancer
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Author : Jing He
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-08

Molecular Diagnostics Of Pediatric Cancer written by Jing He and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-08 with Medical categories.




Pediatric Tumors


Pediatric Tumors
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Author : John T. Kemshead
language : en
Publisher: CRC Press
Release Date : 2020-10-28

Pediatric Tumors written by John T. Kemshead and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Medical categories.


This monograph explains the considerable impact that monoclonal antibodies and molecular probes have had on the diagnosis of tumor types and sub-types. It explains how radiolabelled monoclonal antibodies have also been used as imaging agents to try to improve the oncologist's ability to define residual tumor deposits after combination chemo/radiotherapy. Finally, the childhood malignancies that still have a poor prognosis are presented, and new novel ways of therapy are explained.