Peptides Synthesis And Applications


Peptides Synthesis And Applications
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Peptides


Peptides
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Author : Bernd Gutte
language : en
Publisher: Elsevier
Release Date : 1995-10-24

Peptides written by Bernd Gutte and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-24 with Science categories.


In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. The history of peptide chemistry Amide formation, deprotection, and disulfide formation in peptide synthesis Solid-phase peptide synthesis a-helix formation by peptides in water Stability and dynamics of peptide conformation An overview of structure-function studies of peptide hormones Neuropeptides:peptide and nonpeptide analogs Reversible inhibitors of serine proteinases Design of polypeptides Current capabilities and future possibilities of soluble chemical combinatorial libraries Epitope mapping with peptides Synthesis and applications of branched peptides in immunological methods and vaccines



Peptide Synthesis And Applications


Peptide Synthesis And Applications
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Author : John Howl
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Peptide Synthesis And Applications written by John Howl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.


Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.



Peptide Synthesis And Applications


Peptide Synthesis And Applications
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Author : Knud J. Jensen
language : en
Publisher: Humana
Release Date : 2016-08-27

Peptide Synthesis And Applications written by Knud J. Jensen and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-27 with Science categories.


Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging. The second edition of Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.



Cyclic Peptides


Cyclic Peptides
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Author : Jesko Koehnke
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-12-15

Cyclic Peptides written by Jesko Koehnke and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-15 with Science categories.


This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.



Peptides Synthesis And Applications


Peptides Synthesis And Applications
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Author : Owen Chase
language : en
Publisher: Callisto Reference
Release Date : 2018-02-13

Peptides Synthesis And Applications written by Owen Chase and has been published by Callisto Reference this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-13 with Science categories.


Peptides are short chains of amino acids and are hence also called small proteins. Peptides are very important hormonal functions and regulate the body's metabolism. Peptide hormones trigger the release of fat and the creation of muscles. They also help the body to absorb more amino acids and manage the growth hormone. The research on peptides is very important for those seeking to study human fitness and muscle development. The extensive contents of this book provide the readers with a thorough understanding of the subject. It includes some of the vital pieces of work being conducted across the world, on various topics related to peptides.



Peptide Synthesis


Peptide Synthesis
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Author : Jaya Varkey
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18

Peptide Synthesis written by Jaya Varkey and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Science categories.


Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides.



Peptide Arrays On Membrane Supports


Peptide Arrays On Membrane Supports
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Author : Joachim Koch
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Peptide Arrays On Membrane Supports written by Joachim Koch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.


Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding.



Solid Phase Peptide Synthesis


Solid Phase Peptide Synthesis
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Author : Gregg B. Fields
language : en
Publisher: Academic Press
Release Date : 1997-10-21

Solid Phase Peptide Synthesis written by Gregg B. Fields and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-21 with Medical categories.


The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides



Chemical Approaches To The Synthesis Of Peptides And Proteins


Chemical Approaches To The Synthesis Of Peptides And Proteins
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Author : Paul Lloyd-Williams
language : en
Publisher: CRC Press
Release Date : 2020-08-18

Chemical Approaches To The Synthesis Of Peptides And Proteins written by Paul Lloyd-Williams and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Cooking categories.


Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.



Peptide Applications In Biomedicine Biotechnology And Bioengineering


Peptide Applications In Biomedicine Biotechnology And Bioengineering
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Author : Sotirios Koutsopoulos
language : en
Publisher: Woodhead Publishing
Release Date : 2017-11-16

Peptide Applications In Biomedicine Biotechnology And Bioengineering written by Sotirios Koutsopoulos and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-16 with Technology & Engineering categories.


Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides