Peritoneal Carcinomatosis Principles Of Management
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Peritoneal Carcinomatosis Principles Of Management
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Author : Paul H. Sugarbaker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Peritoneal Carcinomatosis Principles Of Management written by Paul H. Sugarbaker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.
Peritoneal Carcinomatosis
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Author : Paul H. Sugarbaker
language : en
Publisher: Kluwer Academic Publishers
Release Date : 1995-10-01
Peritoneal Carcinomatosis written by Paul H. Sugarbaker and has been published by Kluwer Academic Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-01 with categories.
The dissemination of cancer on peritoneal surfaces has hitherto been regarded as a terminal condition. Only a few patients with ovarian cancer - a disease where there is extreme drug sensitivity - have been maintained in a disease-free state over the long term. The tumour biology questions are as follows: Is the dissemination of cancer on peritoneal surfaces to be regarded as finite spread of malignancy, or as evidence of systematic disease? Is peritoneal carcinomatosis in selected patients a limited process that can be treated for cure, using surgery and chemotherapy? Can treatments lead to a complete resolution of the cancerous process? Most oncologists would regard peritoneal carcinomatosis as a condition that can only be palliated. This book presents the principles that support aggressive management plans with disease eradication as an end point.New technologies have emerged, bringing about this conceptual change in thinking. Technologies have been developed for complete chemotherapeutic treatment of all peritoneal surfaces. Technologies have been developed for uncovering minute foci of disease in remote portions of the abdomen. Also, new surgical and electrosurgical techniques are important aspects of this revised management plan. Even the data management tools required to quantitate improvements in treatment have been developed, and are presented here.The book shows that peritoneal carcinomatosis can be treated and that complete eradication of malignancy can occur.
Intraperitoneal Cancer Therapy
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Author : Wim P. Ceelen
language : en
Publisher: CRC Press
Release Date : 2015-10-22
Intraperitoneal Cancer Therapy written by Wim P. Ceelen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-22 with Medical categories.
Intraperitoneal Cancer Therapy: Principles and Practice is one of the first books to combine the latest clinical developments in the treatment of patients with peritoneal surface disease and the scientific principles that underlie the concept of intraperitoneal cancer therapy. The book covers basic concepts such as anatomy, physiology, pharmacology
Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond
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Author : Aditi Bhatt
language : en
Publisher: Springer
Release Date : 2018-04-02
Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond written by Aditi Bhatt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-02 with Medical categories.
The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.
Peritoneal Carcinomatosis A Multidisciplinary Approach
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Author : wim ceelen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06
Peritoneal Carcinomatosis A Multidisciplinary Approach written by wim ceelen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Illustrations aid the reader throughout in the many facets of this disease. The book will be of particular interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC.
Peritoneal Carcinomatosis Drugs And Diseases
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Author : Paul H. Sugarbaker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Peritoneal Carcinomatosis Drugs And Diseases written by Paul H. Sugarbaker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Peritoneal carcinomatosis dominates the clinical picture of many patients with gastrointestinal, gynecological and urological cancers. For many of them its dev astating effects contribute directly to their death. Most clinicians consider peritoneal carcinomatosis an incurable metastatic disease and give palliative treatment, re stricted to limited surgery and systemic chemotherapy. Contrary to this view, Paul Sugarbaker and his collegues base their approach on the concept that peritoneal carcinomatosis represents regional tumor spread, similar in its impact on treatment and prognosis to that of lymph node metastases in other malignancies. This concept emphasises the value of regional tumor control, as a potentially curative measure. In this book the combination of aggressive cytoreduction and intraperitoneal chemotherapy to control peritoneal carcinomatosis is extensively explored. Basic to this approach is the observation that most cancer cells show only relative resistence against commonly available drugs, which can be overcome by a sufficient increase of drug concentrations in tumor tissue. After intraperitoneal delivery, drugs will reach high tissue concentrations in the superficial few cell layers, while plasma concentrations will remain below toxic levels. Patients with only limited residual tumor at the peritoneal surface after cytoreduction may therefore benefit from intraperitoneal chemotherapy.
Principles And Practice Of Surgical Oncology
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Author : Howard Silberman
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-03-28
Principles And Practice Of Surgical Oncology written by Howard Silberman and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-28 with Medical categories.
Principles and Practice of Surgical Oncology uniquely emphasizes a multidisciplinary, integrated approach to the treatment of solid tumors. It presents treatment strategies that combine surgery with preoperative or postoperative adjunctive chemotherapy, hormonal therapy, and/or radiation therapy to achieve optimal outcome. The book features contributions from surgeons, basic scientists, pathologists, radiologists, radiation therapists, and medical oncologists and offers a comprehensive presentation of genetics, molecular biology, pathogenesis, and multimodal therapeutic approaches. A unique feature of the book is a commentary following each chapter, which describes alternative approaches and discusses controversial areas of current therapy. A companion Website will offer the fully searchable text with images.
Diagnosis And Management Of Ovarian Disorders
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Author : Albert Altchek
language : en
Publisher: Elsevier
Release Date : 2003-09-04
Diagnosis And Management Of Ovarian Disorders written by Albert Altchek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-04 with Medical categories.
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine
Regional Cancer Therapy
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Author : Peter M. Schlag
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-20
Regional Cancer Therapy written by Peter M. Schlag and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-20 with Medical categories.
This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. This book is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.
Advances In Abdominal Surgery 2002
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Author : Attilio Maria Farinon
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Advances In Abdominal Surgery 2002 written by Attilio Maria Farinon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
Advances in Abdominal Surgery 2002 contains papers from a group of Italian academic surgeons who contribute to a national research program entitled `Progress in Abdominal Surgery'. The research is supported by the Italian Ministry of the University. The primary objective of the group is to combine experimental and clinical approaches in the study of several surgical abdominal diseases. The authors of the individual chapters were requested to present an update in their own fields of research. This volume summarizes several important updates in abdominal surgery and pathophysiology. The contributions are grouped into six sections, namely Surgical Infection, Hepatobiliary and Pancreatic and Splenic Surgery, Colorectal Surgery, Fecal Incontinence, Minimally-Invasive Surgery, and Transplantation.