Pet Ct And Mri In Prostate Cancer
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Pet Ct And Mri In Prostate Cancer
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Author : Fabio Grizzi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-03
Pet Ct And Mri In Prostate Cancer written by Fabio Grizzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-03 with Medical categories.
Prostate cancer remains one of the most common cancers and is among the most lethal in men worldwide. It is significant that prostate cancer is identified in the early stages as the disease can be highly metastatic leading to a low survival rate. Therefore, it is essential for patients to have a better prognosis and able to be treated early. The diagnostic tools to identify prostate cancer have developed throughout the years which includes but is not limited to transrectal ultrasound-guided prostate biopsy and histopathology prior to radical prostatectomy. However, biopsies have been found to be invasive in addition to studies demonstrating an underdiagnosis of patients who have advanced prostate cancer.
The Significance Of Replacing Pet Ct With Pet Mri When Imaging Prostate Cancer
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Author : Corey Snitchler
language : en
Publisher:
Release Date : 2007
The Significance Of Replacing Pet Ct With Pet Mri When Imaging Prostate Cancer written by Corey Snitchler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Prostate categories.
Prostate Cancer An Issue Of Pet Clinics E Book
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Author : Harshad R. Kulkarni
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-10-14
Prostate Cancer An Issue Of Pet Clinics E Book written by Harshad R. Kulkarni and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-14 with Medical categories.
In this issue of PET Clinics, guest editors Drs. Harshad R. Kulkarni and Abass Alavi bring their considerable expertise to the topic of Prostate Cancer. PET imaging for prostate cancer continues to evolve as new radiotracers and imaging modalities are combined. This issue offers an up-to-date review of the most popular radiotracers and how PET imaging is combined with MR, CT, and ultrasound to provide the most accurate diagnosis of prostate cancer. Contains 12 practice-oriented topics including the role of ultrasound, CT, and MRI in managing patients with prostate cancer; Ga68 PSMA imaging; PET imaging for prostate cancer using F-18 Fluciclovine; PET imaging for prostate cancer using Ga-68 RM2; the role of NaF PET in the imaging of prostate cancer; and more. Provides in-depth clinical reviews on prostate cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Pet Mri In Oncology
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Author : Andrei Iagaru
language : en
Publisher: Springer
Release Date : 2018-01-23
Pet Mri In Oncology written by Andrei Iagaru and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-23 with Medical categories.
In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists in nuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.
Comparison Of 68ga Hbed Cc Psma Pet Ct And Multiparametric Mri For Gross Tumour Volume Detection In Patients With Primary Prostate Cancer Based On Slice By Slice Comparison With Histopathology
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Author : Constantinos Zamboglou
language : en
Publisher:
Release Date : 2017
Comparison Of 68ga Hbed Cc Psma Pet Ct And Multiparametric Mri For Gross Tumour Volume Detection In Patients With Primary Prostate Cancer Based On Slice By Slice Comparison With Histopathology written by Constantinos Zamboglou and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Abstract: Purpose: The exact detection and delineation of the intraprostatic tumour burden is crucial for treatment planning in primary prostate cancer (PCa). We compared 68Ga-HBED-CC-PSMA PET/CT with multiparametric MRI (mpMRI) for diagnosis and tumour delineation in patients with primary PCa based on slice by slice correlation with histopathological reference material. Methodology: Seven patients with histopathologically proven primary PCa underwent 68Ga-HBED-CC-PSMA PET/CT and MRI followed by radical prostatectomy. Resected prostates were scanned by ex-vivo CT in a special localizer and prepared for histopathology. Invasive PCa was delineated on a HE stained histologic tissue slide and matched to ex-vivo CT to obtain gross tumor volume (GTV-)histo. Ex-vivo CT including GTV-histo and MRI data were matched to in-vivo CT(PET). Consensus contours based on MRI (GTV-MRI), PSMA PET (GTV-PET) or the combination of both (GTV-union/-intersection) were created. In each in-vivo CT slice the prostate was separated into 4 equal segments and sensitivity and specificity for PSMA PET and mpMRI were assessed by comparison with histological reference material. Furthermore, the spatial overlap between GTV-histo and GTV-PET/-MRI and the Sørensen-Dice coefficient (DSC) were calculated. In the case of multifocal PCa (4/7 patients), SUV values (PSMA PET) and ADC-values (diffusion weighted MRI) were obtained for each lesion. Results: PSMA PET and mpMRI detected PCa in all patients. GTV-histo was detected in 225 of 340 segments (66.2%). Sensitivity and specificity for GTV-PET, GTV-MRI, GTV-union and GTV-intersection were 75% and 87%, 70% and 82%, 82% and 67%, 55% and 99%, respectively. GTV-histo had on average the highest overlap with GTV-union (57±22%), which was significantly higher than overlap with GTV-MRI (p=0.016) and GTV-PET (p=0.016), respectively. The mean DSC for GTV-union, GTV-PET and GTV-MRI was 0.51 (±0.18), 0.45 (±0.17) and 0.48 (±0.19), respectively. In every patient with multifocal PCa there was one lesion which had both the highest SUV and the lowest ADC-value (mean and max). Conclusion: In a slice by slice analysis with histopathology, 68Ga-HBED-CC-PSMA PET/CT and mpMRI showed high sensitivity and specificity in detection of primary PCa. A combination of both methods performed even better in terms of sensitivity (GTV-union) and specificity (GTV-intersection). A moderate to good spatial overlap with GTV-histo was observed for PSMA PET/CT and mpMRI alone which was significantly improved by GTV-union. Further studies are warranted to analyse the impact of these preliminary findings for diagnostic (multimodal guided TRUS biopsy) and therapeutic (focal therapy) strategies in primary PCa
Prostate Cancer Imaging And Therapy An Issue Of Pet Clinics E Book
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Author : Richard P. Baum
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-03-11
Prostate Cancer Imaging And Therapy An Issue Of Pet Clinics E Book written by Richard P. Baum and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-11 with Medical categories.
This issue of PET Clinics focuses on Prostate Cancer Imaging and Therapy, and is edited by Drs. Cristina Nanni and Richard P. Baum. Articles will include: Clinicians Need for Imaging of Prostate Cancer; Imaging of Prostate Cancer using 11C-Choline; Imaging of Prostate Cancer using FACBC; Imaging of Prostate Cancer using Ga-Bombesin; Imaging of Prostate Cancer using 18F-Choline; Imaging of Prostate Cancer using Cu-64 Prostate-specific membrane antigen; From bench to bed: New Gastrin releasing peptide receptor-directed radioligands and their use in prostate cancer; Imaging of Prostate Cancer using Ga-68 Prostate-specific membrane antigen; Imaging of Prostate Cancer using F-18 Prostate-specific membrane antigen; Imaging of Prostate Cancer using uPAR-PET; PET/CT for radiation therapy planning of Prostate Cancer; and more!
Radiopharmaceuticals
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Author : Ferdinando Calabria
language : en
Publisher: Springer Nature
Release Date : 2019-10-12
Radiopharmaceuticals written by Ferdinando Calabria and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-12 with Medical categories.
This book provides a rapid and concise guide to PET (PET/CT and PET/MRI) molecular imaging, concentrating extensive information on PET radiopharmaceuticals in a single volume. The book reflects the rapid development of several PET tracers over the last decade, as a result of which the “traditional” PET/CT with 18F-FDG, the “cornerstone” of PET imaging, is now only one of several available options, which use different tracers for different diseases. For the same reason, PET imaging is no longer limited to the field of oncology. In the editors’ experience, students in medicine and residents in nuclear medicine and radiology have limited access to scientific papers concerning novel PET tracers. Moreover, these papers generally focus on a single PET radiopharmaceutical. With approx. 20 radiopharmaceuticals explained in detail and a wealth of images and clinical cases, the book represents a versatile, comprehensive and practice-oriented guide to PET imaging, pursuing a unique and novel approach to the clinical role of PET tracers. The book’s didactic nature also makes it an invaluable tool for residents in nuclear medicine and radiology, as well as for radiographers and clinicians in radiotherapy, oncology, hematology, cardiology and neurology.
Pet Ct And Pet Mri In Oncology
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Author : Patrick Peller
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-09
Pet Ct And Pet Mri In Oncology written by Patrick Peller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-09 with Medical categories.
Over the past decade, PET-CT has achieved great success owing to its ability to simultaneously image structure and function, and show how the two are related. More recently, PET-MRI has also been developed, and it represents an exciting novel option that promises to have applications in oncology as well as neurology. The first part of this book discusses the basics of these dual-modality techniques, including the scanners themselves, radiotracers, scan performance, quantitation, and scan interpretation. As a result, the reader will learn how to perform the techniques to maximum benefit. The second part of the book then presents in detail the PET-CT and PET-MRI findings in cancers of the different body systems. The final two chapters address the use of PET/CT in radiotherapy planning and examine areas of controversy. The authors are world-renowned experts from North America, Europe, and Australia, and the lucid text is complemented by numerous high-quality illustrations.
Pet Ct In Prostate Cancer
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Author : Gary Cook
language : en
Publisher: Springer
Release Date : 2017-07-24
Pet Ct In Prostate Cancer written by Gary Cook and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-24 with Medical categories.
This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, which presents contributions from professionals worldwide who share a common purpose in promoting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
Positron Emission Tomography
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Author : Birendra Kishore Das
language : en
Publisher: Springer
Release Date : 2014-12-04
Positron Emission Tomography written by Birendra Kishore Das and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-04 with Medical categories.
This book provides basic information about the relatively new and evolving technology –positron emission tomography- for its clinical applications and practical guidance for the referring physicians. Chapters cover application of PET in various clinical settings including oncology, cardiology, and neurology with a focus on role in various cancers. Because most of the new PET equipments come as hybrid machines with CT or MRI, two chapters have been included at the end of the book to provide basic and comprehensive information about these two technologies. Molecular imaging is going to revolutionize the way we practice medicine in the future. It will lead to more accurate diagnosis of diseases and its extent which will lead to better management and better outcomes. In the history of medicine no imaging modality has ever become so popular for use in such a short time as has the PET technology. PET imaging is mostly used in oncology, neurology and cardiology but also finds application in other situations such as infection imaging. The main focus, of course, is in management of cancer patients. PET (PET-CT) is not only very sensitive as it can detect changes in abnormal biochemical processes at cellular level but in one go all such areas can be detected in a whole body scan. It can show response to therapy, eradication of the disease or recurrence during the follow-up period. One of the main differences between a PET scan and other imaging tests like CT scan or MRI is that the PET scan reveals the cellular level metabolic changes occurring in an organ or tissue. This is important and unique because disease processes begin with functional changes at the cellular level. A PET scan can detect these very early changes whereas a CT or MRI detect changes much later as the disease begins to cause changes in the structure of organs or tissues. Some cancers, especially lymphoma or cancers of the head and neck, brain, lung, colon, or prostate, in very early stage may show up more clearly on a PET scan than on a CT scan or an MRI. A PET scan can measure such vital functions as blood flow, oxygen use, and glucose metabolism, which can help to evaluate the effectiveness of a patient’s treatment plan, allowing the course of care to be adjusted if necessary. Apart from its vital role in oncology it can estimate brain's blood flow and metabolic activity. A PET scan can help finding nervous system problems, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, transient ischemic attack (TIA), amyotrophic lateral sclerosis (ALS), Huntington's disease, stroke, and schizophrenia. It can find changes in the brain that may cause epilepsy. PET scan is also increasingly being used to find poor blood flow to the heart, which may mean coronary artery disease. It can most accurately estimate the extent of damage to the heart tissue especially after a heart attack and help choose the best treatment, such as coronary artery bypass graft surgery, stenting or medical treatment. It can also contribute significantly in identifying areas exactly where radiotherapy is to be targeted avoiding unnecessary radiation exposure to surrounding tissue.