Pharmacological Advances In Natural Product Drug Discovery
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Pharmacological Advances In Natural Product Drug Discovery
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Author : Guanhua Du
language : en
Publisher: Academic Press
Release Date : 2020-03
Pharmacological Advances In Natural Product Drug Discovery written by Guanhua Du and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03 with categories.
Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the "Medicinal Mix", Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more. Includes the authority and expertise of leading contributors in natural product pharmacology Provides the latest pharmacological research progresses of eight medicinal compounds from natural products Presents a thorough discussion on the compatibility of traditional medicines
Natural Products In Clinical Trials
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Author : Atta-ur- Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2018-03-03
Natural Products In Clinical Trials written by Atta-ur- Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-03 with Medical categories.
Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume brings reviews contributed by eminent scientists in the field. The first volume covers the following topics: - bioactive compounds from marine invertebrates - natural product derived drugs for immunological and inflammatory diseases - clinical trials of curcumin, camptothecin, astaxanthin, and biochanin - antibacterial and antifungal drugs from natural sources - natural products as anti-HIV medicines.
Lead Molecules From Natural Products
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-07-07
Lead Molecules From Natural Products written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-07 with Science categories.
Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.
Natural Product Chemistry For Drug Discovery
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Author : Antony D. Buss
language : en
Publisher: Royal Society of Chemistry
Release Date : 2010
Natural Product Chemistry For Drug Discovery written by Antony D. Buss and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.
Natural Products
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Author : Lixin Zhang
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-17
Natural Products written by Lixin Zhang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-17 with Medical categories.
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural Bio Active Compounds
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Author : Mallappa Kumara Swamy
language : en
Publisher: Springer Nature
Release Date : 2019-09-19
Natural Bio Active Compounds written by Mallappa Kumara Swamy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-19 with Science categories.
Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry, nature remains an essential resource for drug discovery. Therefore, more and more researchers are interested in understanding the chemistry, clinical pharmacology, and beneficial effects of bioactive compounds in connection with solving human health problems. This book presents a wealth of information on natural metabolites that have been or are currently being used as drugs or leads for the discovery of new drugs. In addition, it highlights the importance of natural products against various human diseases, and their applications in the drug, nutraceuticals, cosmetics and herbal industries. Accordingly, the book offers a valuable resource for all students, educators, and healthcare experts involved in natural product research, phytochemistry, and pharmacological research.
Natural Products And Drug Discovery
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Author : Subhash C. Mandal
language : en
Publisher: Elsevier
Release Date : 2018-02-16
Natural Products And Drug Discovery written by Subhash C. Mandal and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-16 with Science categories.
Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers. Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout
Advanced Pharmacological Uses Of Medicinal Plants And Natural Products
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Author : Singh, Ajeet
language : en
Publisher: IGI Global
Release Date : 2020-02-21
Advanced Pharmacological Uses Of Medicinal Plants And Natural Products written by Singh, Ajeet and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-21 with Medical categories.
A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.
Discovery And Development Of Anti Inflammatory Agents From Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2019-07-11
Discovery And Development Of Anti Inflammatory Agents From Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with Science categories.
Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products. Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases. Features contributions from active researchers and leading experts working in medicinal natural products and herbal formulations Includes recent, cutting-edge advances on medicinal natural products, along with preventative therapies for different kinds of inflammation-directed diseases Offers an authoritative source of information on the industrial application of natural products for medicinal purposes
Drug Discovery And Design Using Natural Products
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Author : Jorddy Neves Cruz
language : en
Publisher: Springer
Release Date : 2023-08-28
Drug Discovery And Design Using Natural Products written by Jorddy Neves Cruz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Medical categories.
Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.