Pharmacological And Toxicological Screening Methods I
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Pharmacological And Toxicological Screening Methods I
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Author : Dr. Trilochan Satapathy
language : en
Publisher: JEC PUBLICATION
Release Date :
Pharmacological And Toxicological Screening Methods I written by Dr. Trilochan Satapathy and has been published by JEC PUBLICATION this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
The sciences of pharmacology and toxicology are strongly intertwined. The former focuses on how medications function in live beings, while the latter focuses on the bad effects of drugs and chemicals and how to treat them. Both fields are concerned with the behaviour of drugs and chemicals in living organisms. This book provides a detailed illustration of the most important concepts that are involved in pharmacology and the medical sciences that are related to it. The title opens with a discussion of the historical elements of drug creation, including up-to-date information about Nobel Laureates in pharmacology and toxicology and the key discoveries they made. Following this, it conducts an analysis of the fundamental concepts of pharmacology, including pharmacokinetics and pharmacodynamics, as well as providing comprehensive information on drug transporters and interactions. The subsequent chapters of the book are dedicated to covering a comprehensive assortment of subjects that provide vital knowledge on the fundamental principles of pharmacology and the manner in which these concepts are used for the clinical treatment of disorders.
Pharmacological Screening Methods And Toxicology
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Author : A Srinivasa Rao
language : en
Publisher:
Release Date : 2016
Pharmacological Screening Methods And Toxicology written by A Srinivasa Rao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
This Book covers all steps of drug discovery like lead synthesis, preclinical studies, FDA requirements and clinical studies and also about High Throughput Screening. It also covers about all aspects about experimental animals.
Screening Methods In Pharmacology
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Author : Robert A. Turner
language : en
Publisher: Elsevier
Release Date : 2016-01-26
Screening Methods In Pharmacology written by Robert A. Turner and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-26 with Medical categories.
Screening Methods in Pharmacology, Volume II is a collection of papers that presents practical techniques and information on the selection of a screening program for a particular pharmacological activity. The book contains the most reliable, simplest, and the most preferred screening methods in pharmacology. The text presents screening methods for alpha and beta Adrenergic blocking agents; compounds for antianginal activity; topical products for excessive eccrine sweating; antidepressant agents; and agents with analgesic and analgesic antagonist activity. Pharmacologists, pharmacists, researchers, and physicians will find this book a good source of information.
Screening Methods In Pharmacology
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Author : Robert Arnold Turner
language : en
Publisher:
Release Date : 1971
Screening Methods In Pharmacology written by Robert Arnold Turner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Drugs categories.
Introduction To Toxicological Screening Methods And Good Laboratory Practice
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Author : Saravana Babu Chidambaram
language : en
Publisher: Springer Nature
Release Date : 2022-02-11
Introduction To Toxicological Screening Methods And Good Laboratory Practice written by Saravana Babu Chidambaram and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-11 with Medical categories.
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.
Pharmacological Screening Methods Toxicology
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Author : Avanapu Srinivasa Srinivasa Rao
language : en
Publisher:
Release Date : 2021-11
Pharmacological Screening Methods Toxicology written by Avanapu Srinivasa Srinivasa Rao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11 with categories.
Pharmacological And Toxicological Screening Methods Ii
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Author : Dr. Trilochan Satapathy
language : en
Publisher: JEC PUBLICATION
Release Date :
Pharmacological And Toxicological Screening Methods Ii written by Dr. Trilochan Satapathy and has been published by JEC PUBLICATION this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
A complete handbook on toxicology covers basic principles, regulatory criteria, and sophisticated methods for understanding and assuring the safety of varied chemicals in the following pages. Introduction to toxicology, "Toxicology Fundamentals and Regulatory Guidelines," covers broad overviews, mechanistic toxicology, regulatory frameworks, and descriptive toxicology. Focus is on OECD, ICH, EPA, and Schedule Y regulatory criteria, as well as the history and importance of Good Laboratory Practise (GLP) in drug development. As the book explores "Types of Toxicity Studies and Test Item Characterization," it examines acute, sub-acute, chronic, and particular acute investigations, including oral, cutaneous, and inhalational toxicity studies. Test item characterisation procedures are carefully explained, emphasising their importance in regulatory compliance and toxicity evaluation. This leads to "Advanced Toxicology Studies," which covers reproductive toxicology, genotoxicity, and in vivo carcinogenicity. These investigations provide a thorough view of possible dangers and evaluate drug safety. The book then discusses "IND Enabling Studies and Safety Pharmacology," which covers the necessary research for IND applications. Exploring regulatory settings, corporate views, and safety pharmacology in drug development provides a complete knowledge of experimental substance safety. The third part, "Toxicokinetic and Alternatives to Animal Testing," emphasises toxicokinetic assessment and discusses new methods. Following the evolution of safety assessment practises, these options are investigated for ethical and regulatory consequences. Students, researchers, and professionals traversing toxicology's difficult landscape may find this book invaluable. Its extensive coverage, from basic concepts to sophisticated approaches, makes it an important tool for protecting humans and ecosystems in the dynamic pharmaceuticals and beyond industries.
Screening Methods In Pharmacology
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Author : Robert A. Turner
language : en
Publisher:
Release Date : 1971
Screening Methods In Pharmacology written by Robert A. Turner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with categories.
Screening Methods In Pharmacology
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Author : Robert A. Turner
language : en
Publisher:
Release Date : 1979
Screening Methods In Pharmacology written by Robert A. Turner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with categories.
Screening Methods In Pharmacology
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Author : N. S. Parmar
language : en
Publisher: Alpha Science International, Limited
Release Date : 2006
Screening Methods In Pharmacology written by N. S. Parmar and has been published by Alpha Science International, Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Animal experimentation categories.
Screening Methods in Pharmacology provides an up to-date and concise account of in vivo methods used in the pharmacological screening of important categories of clinically useful drugs. It also encompasses the basic principles of animal experimentation and current advances leading to the use of transgenic animals, combinatorial chemistry, high throughout screening, pharmacogenomics, proteomics and array technology. The methods used for the detection of pharmacological effects of potential drugs on the CNS, CVS, endocrines, respiratory tract and immunomodulation have been described in adequate details with cross references for further studies and comprehension. The book is expected to be extremely useful for postgraduates in pharmacology from all disciplines and for the scientists engaged in the drug discovery research programmes.