Pharmacological Studies On Synaptic Transmission On The Central Nervous System
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Pharmacological Studies On Synaptic Transmission On The Central Nervous System
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Author : Ian McCance
language : en
Publisher:
Release Date : 1969
Pharmacological Studies On Synaptic Transmission On The Central Nervous System written by Ian McCance and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Central nervous system categories.
Drugs And Central Synaptic Transmission
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Author : P. B. Bradley
language : en
Publisher:
Release Date : 1976
Drugs And Central Synaptic Transmission written by P. B. Bradley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.
Pharmacology Of Central Synapses
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Author : V. V. Zakusov
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Pharmacology Of Central Synapses written by V. V. Zakusov and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Pharmacology of Central Synapses deals with the pharmacology of the central nervous system and the mode of action of neurotropic drugs based on their influence on synaptic transmission. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological, and biochemical findings, form the conceptual basis of this book. Comprised of eight chapters, this book examines the effect of neurotropic drugs on the synaptic transmission in reflex, projection, and association (commissural) tracts. The specific effects of various narcotics, neuroleptics, tranquillizers, analgesics, antidepressants, and stimulants on synaptic transmission in various structures of the central nervous system and at its different levels are described. This text also considers the differences in the sensitivity to such drugs of various synapses and their influence on the selectivity of drug action. This book explains the influence of neurotropic drugs on such aspects of nervous activity as impulse summation, after-discharge and functional lability, central inhibition, and the neurochemical mechanisms, particularly those involving monoaminergic, cholinergic, serotoninergic, and GABA-ergic components of synaptic transmission. The final chapter focuses on the effect of psychotropic drugs on behavior. This book will be helpful to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.
The Pharmacology Of Synapses
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Author : J. W. Phillis
language : en
Publisher: Elsevier
Release Date : 2013-10-22
The Pharmacology Of Synapses written by J. W. Phillis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
The Pharmacology of Synapses details the advancements in the understanding of synaptic pharmacology. The book examines the development in various areas of synaptic pharmacology research. The text first covers the basic concepts of synaptic pharmacology, and then proceeds to tackling the metabolism of acetylcholine. Next, the selection deals with monoamine in the central nervous system, and neuromuscular transmission in vertebrates. The text also discusses the pharmacology of autonomic ganglia. Chapters 7 and 8 detail the pharmacological studies on neurons in the brain and spinal cord. The ninth chapter deals with the neuromuscular transmission in invertebrates, while the 10th chapter deals with drugs, transmission, and molluskan neurons. The book will be of great use to researchers and practitioners of pharmacology, neurology, biological psychology, and psychiatry.
Cns Neurotransmitters And Neuromodulators
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Author : Trevor W. Stone
language : en
Publisher: CRC Press
Release Date : 2020-10-28
Cns Neurotransmitters And Neuromodulators written by Trevor W. Stone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Science categories.
The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject. This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.
Modulation Of Synaptic Transmission And Plasticity In Nervous Systems
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Author : Georg Hertting
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Modulation Of Synaptic Transmission And Plasticity In Nervous Systems written by Georg Hertting and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
This volume is based on a workshop "Modulation of Synaptic Transmission and Plasticity in Nervous Systems" held in n Ciocco, Castelvecchio, Pascoli, Italy, from September 8th to 13th, 1987. The purpose of the meeting was to bring together scientists working on plasticity in nervous systems on different levels. The contributions can be subgrouped into six fields of research: 1) Presynaptic Modulation of Chemical Neurotransmission 2) Postsynaptic Signal Transduction 3) Modulation of Synaptic Transmission and Plasticity in the Hippocampus 4) Modulation of Neuromuscular Transmission 5) Molecular and Cellular Analysis of Conditioning in Marine Snails 6) Analysis of Learning and Memory in Insects Understanding how nervous systems and in particular our brain processes and stores information has been a major challenge in science for centuries and will remain for some time to come. Not until recently neurobiologists agreed to seek plasticity of behavior primarily in the modulation of the properties of synapses between nerve cells. This is to be understood within the context provided by a neural circuitry. An important stimulus came from the work on the marine snail Aplysia, where learning processes can be described as a modulation of transmitter release, traced back to a complete chain of molecular events in an identified neuron. Learning became a topic of molecular biology. Three systems appear particularly promising for this approach: insects, in particular Drosophila, marine snails and the mammalian hippocampal tissue. Our views on neurotransmission have rapidly changed.
Mechanisms Of Synaptic Transmission
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Author : Joseph D. Robinson
language : en
Publisher: Oxford University Press
Release Date : 2001-05-17
Mechanisms Of Synaptic Transmission written by Joseph D. Robinson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-17 with Medical categories.
Synaptic transmission plays a central role in the nervous system as the mechanism that allows for chemical and electrical communication between cells and thus connects discrete elements into the functioning whole. This is a broad account of anatomical, biochemical, embryological, medical, pathological, pharmacological, and physiological studies on synaptic transmission during the hundred years beginning in 1890. During this century, the process of synaptic transmission came to be recognized not only as the most fundamental neurophysiological process, but also as a seat of pathological changes, and as the predominant site of action for drugs used to treat a wide range of psychiatric and neurological disorders. At the same time, research from these various disciplines was transformed into a new and unifying field, neuroscience. The course of these investigations reveals ingenious experiments, powerful new techniques, and imaginative insights. The author describes broadly who did what, when, where, and how (and, in cases where it is apparent, why) and uses experimental results and interpretations to display the evolutionary course to our current understanding of how nerve cells communicate: the basic principle of neural functioning. The book will be of interest to basic and clinical neuroscientists, pharmacologists, and physiologists, to historians and philosophers of the life sciences and medicine, and to their respective students.
Central Cholinergic Synaptic Transmission
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Author : Frotscher
language : en
Publisher: Birkhäuser
Release Date : 2013-03-07
Central Cholinergic Synaptic Transmission written by Frotscher and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Science categories.
Our knowledge of cholinergic synaptic transmission in the peripheral nervous system (PNS) has expanded enormously since the early 1930's, at which time O. Loewi discovered chemical neurotransmission through acetylcholine (ACh) and the pharmacological actions of ACh were described by H. Dale and his colleagues. Description of ACh's actions and receptors in various parts of the brain was followed by a detailed analysis of ACh's synthesis, release mechanism, removal from the synaptic cleft, modes of agonist-receptor interactions, properties of regulated conductances and of the pre-and postsynaptic modulation of cholinergic synapses. Our knowledge has been increasingly consolidat ing, leading us to the recent clarification of the structure of the periph eral nicotinic receptor-ion channel and its functional properties. It is appropriate to maintain the claim that the fundamentals of our under standing of synaptic transmission come from studies on cholinergic synapses in the PNS. Contrastingly, views held on the role of cholinergic synapses in the mammalian central nervous system (CNS) are extremely controversial, although it has been clear for some time that ACh is present in the brain. Illustrating this, no unanimous view is held on the role of nicotinic receptors in the CNS. There is one notable exception to this confusion: Studies begun by J. C. Eccles and associates in the 1960's and completed by D. R. Curtis and R. W.
The Nervous System
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Author : Walter S. Root
language : en
Publisher: Elsevier
Release Date : 2013-10-22
The Nervous System written by Walter S. Root and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Physiological Pharmacology: A Comprehensive Treatise, Volume II: The Nervous System — Part B, Central Nervous System Drugs focuses on the effects of drugs on the functions of the central nervous system. The selection first offers information on depressant and anticonvulsant drugs. Topics include neurophysiological substrate of drug action; pharmacological properties of selected muscle relaxants; anticonvulsants and their mechanisms; and definitive seizure mechanisms. The book also takes a look at antitussive drugs and psychic energizers and antidepressant drugs. The publication examines emetic and antiemetic drugs, as well as neural mechanisms of emesis, emetic syndromes and agents, and antiemetic agents. The text also reviews the effects of drugs on the eyes and synoptic transmission in the central nervous system. Discussions focus on the effect of drugs used in the therapy of ocular disease; undesirable eye effects of ophthalmic and other drugs; and chemical transmitters in the central nervous system. The selection is a dependable reference for readers interested in the effects of drugs on the central nervous system.
Gabaergic Synaptic Transmission
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Author : Giovanni Biggio
language : en
Publisher: Raven Press (ID)
Release Date : 1992
Gabaergic Synaptic Transmission written by Giovanni Biggio and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
Reviews research on the pharmacology and physiopathology of GABA receptors in the mammalian central nervous system. The coverage ranges from molecular biology, to molecular and clinical pharmacology, to new approaches to pharmacotherapy of convulsive, sleep, and anxiety disorders.