Pharmacology Of Hormones

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Pharmacology Of Hormones

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Author : M. Tausk
language : en
Publisher: Year Book Medical Publishers, Incorporated
Release Date : 1975

Pharmacology Of Hormones written by M. Tausk and has been published by Year Book Medical Publishers, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Hormone therapy categories.

Endocrine Pharmacology

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Author : P. J. Bentley
language : en
Publisher: CUP Archive
Release Date : 1980

Endocrine Pharmacology written by P. J. Bentley and has been published by CUP Archive this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.

A 1981 treatment of the action and uses of the hormones and drugs that influence endocrine functions in the body as seen by a pharmacologist. The book includes a description of available drug preparations and expected therapeutic responses, and an examination of their side effects and interactions with other drugs. Special emphasis is placed on how such drugs and hormones work and on how their biological effects are related to their chemical structures. The physiological background to the practical significance of such substances is given for both a healthy and a diseased state. The book assumes little prior knowledge of endocrinology or pharmacology.

Principles Of Endocrine Pharmacology

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Author : John A. Thomas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Principles Of Endocrine Pharmacology written by John A. Thomas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

The authors have provided an overview of the relationships between hormones that are physiologic constituents of the body as well as their pharmacologic use in replacement therapies and related endocrine dys function. Principles of Endocrine Pharmacology concerns itself with the ther apeutic use of hormones, and hormone like substances, or drugs that can act either by suppressing or enhancing the metabolism of certain glands of internal secretion. Other drugs used for nonendocrine ther apies can likewise affect the endocrine system. Endocrine pharmacology emerged in the early 1900s with the use of crude pituitary extracts. By the mid-1900s several investigators had isolated and begun to synthesize hormones or hormonelike substances. Recognizing the limited supply of hormones that could be obtained both from animal sources and human autopsy material, the search for so called hormone substitutes also began early in the 1900s. Recently, re combinant DNA technologies have been used to provide alternative therapeutic sources of human insulin and human growth hormone. Aside from insulin, perhaps no other use of hormonally-active sub stance is better exemplified by those drugs which affect fertility. The synthesis of an orally-effective steroid represented one of the first major breakthroughs in the chemical suppression of ovulation. Since the orally active 19-norsteroids were introduced in the 1950s, several oral contra ceptive steroid preparations have been marketed. Indeed, the advent of oral contraceptives for birth control has led to a renewed interest in endocrine pharmacology.

Pharmacology Of Hormonal Polypeptides And Proteins

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Author : Nathan Back
language : en
Publisher: Springer
Release Date : 2013-12-11

Pharmacology Of Hormonal Polypeptides And Proteins written by Nathan Back and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-11 with Medical categories.

It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the first phase, when there is only an inflow from the circulation and stor age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.

Pharmacology Of Hormones

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Author : Marius Tausk
language : en
Publisher:
Release Date : 1975

Pharmacology Of Hormones written by Marius Tausk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.

Synopsis Of Endocrine Pharmacology

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Author : John A. Thomas
language : en
Publisher:
Release Date : 1973

Synopsis Of Endocrine Pharmacology written by John A. Thomas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Hormone therapy categories.

Progress In Hormone Biochemistry And Pharmacology

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Author : M. Briggs
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Progress In Hormone Biochemistry And Pharmacology written by M. Briggs and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Somatostatin was discovered in 1971, by Guillemin and his colleagues during their search for the hypothalamic growth hormone-releasing factor. A peptide was found in ovine hypothalamus which inhibited the release of growth hormone from cultured anterior pituitary cells. 1,2 Determination 3 of its amino acid sequence indicated that it was a tetradecapeptide with a molecular weight of 1639 (Figure lJ. An identical peptide was later isolated from porcine hypothalamus by Schally and his coworkers. 4 The peptide was named somatostatin in the belief that it was a hypothalamic releasing factor whose sole function was to inhibit the secretion of growth hormone. It soon became evident, however, that a peptide with identical immunologic characteristics and biologic activity was present in the D cells of pancreatic islets, in D-like cells of the gastrointestinal tract, in parafollicular cells of the thyroid gland, and in extrahypo thalamic neurons of both the central and peripheral nervous system in various species, including man. Moreover, studies employing synthetic somatostatin5 demonstrated that the peptide possessed a wide spectrum of biologic activities in addition to its inhibition of growth hormone. 56 S 0 MAT 0 S TAT I N 6 1 2 3 4 5 7 Ala-Gly-Cys-Lys-Asn-Phe-Phe I I S Trp 8 ~ L~S 9 I I Cys-Ser-Thr-Phe-Thr 14 13 12 11 10 FIG. 1: Structure of somatostatin 57 II. GENERAL DISTRIBUTION AND ACTIONS Somatostatin is widely distributed within both the central and peripheral nervous systems and in various other tissues (Table 1).

Hypothalamic Hormones

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Author : Marcella Motta
language : en
Publisher:
Release Date : 1975

Hypothalamic Hormones written by Marcella Motta and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Nature categories.

Hormonal Steroids Biochemistry Pharmacology And Therapeutics

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Author : L Martini
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Hormonal Steroids Biochemistry Pharmacology And Therapeutics written by L Martini and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.

Hormonal Steroids: Biochemistry, Pharmacology, and Therapeutics, Volume I focuses on various research on steroids and their biological and medical involvements. Comprised of 60 chapters, the book presents the literature of various authors who have conducted research on the relationship between hormonal steroids and biochemistry, pharmacology, and therapeutics. The discussions start with the identification of steroids with hormone-like activities. This discussion includes the nature, compositions, properties, possible uses, and reactions of these hormones when exposed to different conditions and controlled environments. The book then proceeds with discussions on synthesis and metabolism of hormonal steroids. These discussions are supported by graphical representations, reviews, recommendations, and methodologies. The book then explains the control of synthesis and release of steroid hormones. This part notes the relationship of renal and adrenal hormones; the control and production of corticosterone; neurosecretion and control of the pituitary gland; and release of ovulating hormones. The book also highlights the mechanism of steroid action, noting the probable interrelationships of steroids, nonsteroids, intermediary metabolism, and inflammation. Various research are presented on the possible clinical applications of steroids. The text is a vital reference for readers who are interested in the study of hormones.

Advances In Steroid Biochemistry And Pharmacology

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Author : M. H. Briggs
language : en
Publisher: Elsevier
Release Date : 2014-06-28

Advances In Steroid Biochemistry And Pharmacology written by M. H. Briggs and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-28 with Science categories.

Advances in Steroid Biochemistry and Pharmacology, Volume 4 provides information pertinent to the fundamental aspects of steroid biochemistry and pharmacology. This book covers a variety of topics, including cellular biochemistry, pituitary hormones, corticosteroids, and steroid hormones. Organized into seven chapters, this volume begins with an overview of the potential effects of steroids on cellular biochemistry. This text then examines the development of sleep-monitoring methods, together with methods of plasma sampling that enable very frequent specimen to be taken without disturbing the subject. Other chapters consider the usefulness of sleep-related growth hormone release in diagnosis in both children and adult. This book discusses as well the versatile effect of corticosteroids on the cellular components of the connective tissue. The final chapter deals with the functioning of the adrenal cortex and its control by adrenocorticotropic hormone (ACTH). This book is a valuable resource for biochemists, histochemists, biologists, pharmacologists, clinicians, and experimental endocrinologists.