Philosophy Of Systems Biology
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Philosophy Of Systems Biology
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Author : Sara Green
language : en
Publisher: Springer
Release Date : 2016-12-15
Philosophy Of Systems Biology written by Sara Green and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-15 with Science categories.
The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.
Systems Biology
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Author : Fred Boogerd
language : en
Publisher: Elsevier
Release Date : 2007-03-20
Systems Biology written by Fred Boogerd and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-20 with Computers categories.
Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies. * Answers the question of what distinguishes the living from the non-living * An in-depth look to a vigorous and expanding discipline, from molecule to system * Explores the region between individual components and the system
Systems Biology
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Author : Fred C. Boogerd
language : en
Publisher:
Release Date : 2007
Systems Biology written by Fred C. Boogerd and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
The Philosophy Of Biology
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Author : Kostas Kampourakis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-18
The Philosophy Of Biology written by Kostas Kampourakis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-18 with Philosophy categories.
This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.
Processes Of Life
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Author : John Dupré
language : en
Publisher: Oxford University Press
Release Date : 2012-01-26
Processes Of Life written by John Dupré and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-26 with Philosophy categories.
John Dupré explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and society. He reveals how the advance of genetic science is changing our view of the constituents of life, and shows how an understanding of microbiology will overturn standard assumptions about the living world.
Contextualizing Systems Biology
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Author : Martin Döring
language : en
Publisher: Springer
Release Date : 2015-12-18
Contextualizing Systems Biology written by Martin Döring and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-18 with Science categories.
This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists working in the interdisciplinary areas of systems biology, synthetic biology, molecular biology, biology, the philosophy of science, the sociology of science and scientific knowledge, science and technology studies, technology assessment and the like. The authors of this monograph share the theoretical methodological premise that science is a culturally and socially embedded practice which characterizes our culture as a scientific one and at the same time draws its innovative potential from its socio-cultural context. This dialectic relationship lies at the heart of the current development of systems biology which is conceived as a so-called successor of ‘-omics’ research and triggered by high-throughput information technologies. At the same time a need for a holistic conceptualization of complex biological processes emerges. The title Contextualizing Systems Biology suggests that this book analyzes the development and advent of systems biology from different theoretical and methodological perspectives. We investigate a variety of contexts ranging from the analysis of cognitive contexts (such as basic theoretical concepts) to regulative contexts (policies) to the concrete application of a systems biology in the socio-scientific context of a European research project. In empirically analyzing these different and interrelated layers and dimensions of systems biology, the scope of the book goes beyond present attempts to investigate the advent of new approaches in the biological sciences as it frames and assesses systems biology from an interdisciplinary and integrated perspective.
The Conceptual Foundations Of Systems Biology
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Author : James A. Marcum
language : en
Publisher:
Release Date : 2009
The Conceptual Foundations Of Systems Biology written by James A. Marcum and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Philosophy categories.
James Marcum provides an analysis of the fundamental concepts that constitute the foundations of contemporary systems biology. These concepts include holism, emergentism, and robustness, and are compared to the concepts, reductionism, mechanism, and homeostasis, which form the foundations of molecular biology. In an introductory chapter, a brief history of systems biology is reconstructed, along with the issues surrounding the definition and methodology of systems biology, and a discussion of chaos and complexity theories and their relationship to systems biology. Also included in the chapter is a discussion of whether contemporary systems biology represents a Kuhnian paradigm shift or scientific revolution. In the next three chapters, the fundamental concepts of holism, emergentism, and robustness are examined in detail. The notion of holism is discussed first, since it is the major characteristic of systems biology. It is developed in response to the notion of reductionism, which historically is the main approach to the investigation of complex natural phenomena. The notion of emergence is explored in the next chapter and entails the process by which complex phenomena and their properties appear at higher levels of organisation. It is compared to the notion of mechanism, which molecular biologists use to explain ultimately natural phenomena. The final fundamental concept, robustness, is discussed in a following chapter and is contrasted to the notion of homeostasis. It refers to the functional capability or property of a system to maintain its integrity and performance in response to either internal or external perturbations or disturbances, which could compromise a system's stability. In a fifth chapter, cancer is used as a case study to exemplify systems biology's conceptual foundations as applied to disease. In a penultimate chapter, the challenges facing systems biology are discussed, along with the challenges facing its application to cancer biology. In a concluding chapter, the question is addressed whether systems biology is a revolutionary replacement of molecular biology for investigating and understanding biological phenomena.
Philosophy Of Stem Cell Biology
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Author : M. Fagan
language : en
Publisher: Springer
Release Date : 2013-01-21
Philosophy Of Stem Cell Biology written by M. Fagan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-21 with Science categories.
This examination of stem cell biology from a philosophy of science perspective clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. Relations to systems biology and clinical medicine are also discussed.
Information And Living Systems
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Author : George Terzis
language : en
Publisher: MIT Press
Release Date : 2011-04-15
Information And Living Systems written by George Terzis and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-15 with Philosophy categories.
The informational nature of biological organization, at levels from the genetic and epigenetic to the cognitive and linguistic. Information shapes biological organization in fundamental ways and at every organizational level. Because organisms use information—including DNA codes, gene expression, and chemical signaling—to construct, maintain, repair, and replicate themselves, it would seem only natural to use information-related ideas in our attempts to understand the general nature of living systems, the causality by which they operate, the difference between living and inanimate matter, and the emergence, in some biological species, of cognition, emotion, and language. And yet philosophers and scientists have been slow to do so. This volume fills that gap. Information and Living Systems offers a collection of original chapters in which scientists and philosophers discuss the informational nature of biological organization at levels ranging from the genetic to the cognitive and linguistic. The chapters examine not only familiar information-related ideas intrinsic to the biological sciences but also broader information-theoretic perspectives used to interpret their significance. The contributors represent a range of disciplines, including anthropology, biology, chemistry, cognitive science, information theory, philosophy, psychology, and systems theory, thus demonstrating the deeply interdisciplinary nature of the volume's bioinformational theme.
Systems Biology And Its Methodology
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Author : Constantinos Mekios
language : en
Publisher: VDM Publishing
Release Date : 2007
Systems Biology And Its Methodology written by Constantinos Mekios and has been published by VDM Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Philosophy categories.
Within the past decade, Systems Biology (SB) has emerged as an ambitious new approach to the study of complex biological systems. Despite its remarkable impact on biology and beyond, however, the approach remains largely undefined with respect to the fundamental question of its identity: What is SB? In this study, a preliminary answer is sought in a consideration of SB's historical relationship to General System Theory, a topography of its multidisciplinary character, and an analysis of two cases from the scientific literature illustrating the application of its method in the laboratory. The resulting characterization of SB permits the exploration of philosophical questions regarding its methodology: Does it represent an alternative to reductionism? What is the promise that it holds for the future of biology and what are the limits of its potential? Finally, what are its implications for the scientific status of biology, the unity of science project, and the philosophy of biology? Given the scope of its analysis, this book might interest both philosophically inclined biologists and philosophers of biology, as well as, more generally, readers who think critically about the methodology of science.