Physicochemical Methods In The Study Of Biomembranes

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Physicochemical Methods In The Study Of Biomembranes
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Author : Herwig J. Hilderson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Physicochemical Methods In The Study Of Biomembranes written by Herwig J. Hilderson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
In mammalian cells many physiological processes rely on the dynamics of the organization of lipids and proteins in biological membranes. The topics in this volume deal with physicochemical methods in the study of biomembranes. Some of them have a long and respectable history in the study of soluble proteins and have only recently been applied to the study of membranes. Some have tradi tionally been applied to studies of model systems of lipids of well-defined com position, as well as to intact membranes. Other methods, by their very nature, apply to organized bilayers comprised of both protein and lipid. Van Meer and van Genderen provide us with an introduction to the field (Chapter I). From their personal perspective regarding the distribution, trans port, and sorting of membrane lipids, they formulate a number of biologically relevant questions and show that the physicochemical methods described in this book may contribute in great measure to solving these issues. The methods of analytical ultracentrifugation have served faithfully for 60 years in the study of water-soluble proteins. The use of detergent extraction of membrane proteins, and the manipulation of density with H20/D20 mixtures, has extended this technique to the study of proteins, and in particular their interactions, from biological membranes. As described by Morris and Ralston in Chapter 2, this technique can be used to determine a number of important properties of proteins.
Lipid Bilayers
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Author : J. Katsaras
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Lipid Bilayers written by J. Katsaras and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
A general review of lipid bilayer structure and dynamics is given, including such current topics as the hydration of lipid bilayers, the superstructural behaviour of bilayers at different states of hydration and external conditions, the role and behaviour of lipid bilayers on fusion and rupture and the interaction of lipid bilayers with small organic molecules and additives and of protein lipid bilayer interactions. In addition, recent research on lipid interaction with proteins and other molecules in monolayers is reviewed, and the use of highly aligned samples under biologically relevant conditions and the benefits derived from such preparations are addressed. Finally, the latest approach in simulation of impurities within a lipid bilayer is introduced. This book will be a comprehensive review of the current state of biologically relevant model membrane systems which will become an indispensible reference for the "working biophysicist".
Subcellular Biochemistry
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Author : J. Robin Harris
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Subcellular Biochemistry written by J. Robin Harris and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
In Volume 25, leading experts present studies on the value of increased ascorbic acid intake and explore its specific contributions to human and animal health.
Pumps Channels And Transporters
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Author : Ronald J. Clarke
language : en
Publisher: John Wiley & Sons
Release Date : 2015-10-12
Pumps Channels And Transporters written by Ronald J. Clarke and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-12 with Science categories.
Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions
Membrane Active Peptides
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Author : Miguel A. R. B. Castanho
language : en
Publisher: Internat'l University Line
Release Date : 2010
Membrane Active Peptides written by Miguel A. R. B. Castanho and has been published by Internat'l University Line this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Food Colloids Biopolymers And Materials
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Author : Eric Dickinson
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Food Colloids Biopolymers And Materials written by Eric Dickinson and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Technology & Engineering categories.
Food scientists aim to control the taste and texture of existing food products and to formulate new structures of high quality using novel combinations of ingredients and processing methods. Food Colloids, Biopolymers and Materials describes the physical chemistry and material science underlying the formulation and behaviour of multi-phase food systems and includes: * descriptions of new experimental techniques * recent food colloids research findings * authoritative overviews of conceptual issues Essential new findings are presented and emphasis is placed on the interfacial and gelation properties of food proteins, and the role of colloidal and biopolymer interactions in determining the properties of emulsions, dispersions, gels and foams. Specific topics include: confocal microscopy; diffusing wave spectroscopy; protein-polysaccharide interactions; biopolymer phase separation; fat crystallization; bubble/droplet coalescence; and bulk and surface rheology. This book is the latest addition to the highly regarded food colloid series published by the Royal Society of Chemistry and is of relevance to those working and researching in food science and surface and colloid science.
Biology Of The Lysosome
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Author : John B. Lloyd
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biology Of The Lysosome written by John B. Lloyd and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Volume 27 provides a comprehensive review of current knowledge of lysosome function in mammalian cells. The book's unique contribution is its series of chapters that offers unparalleled treatment of the metabolic activities of lysosomes.
Phospholipid Metabolism In Apoptosis
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Author : Peter J. Quinn
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-18
Phospholipid Metabolism In Apoptosis written by Peter J. Quinn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-18 with Science categories.
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. The number of publications on the topic has increased from nothing in the early 1980s to more than 10,000 papers annually today. It is now well recognized that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The idea that life requires death seems somewhat paradoxical, but cell suicide is essential for an animal to survive. For example, without selective destruction of “non-self” T cells, an animal would lack immunity. Similarly, meaningful neural connections in the brain are whittled from a mass of cells. Further, developmental cell remodeling during tissue maturation involves programmed cell death as the major mechanism for functional and structural safe transition of undifferentiated cells to more specialized counterparts. Apoptosis research, with roots in biochemistry, developmental and cell biology, genetics, and immunology, embraces this long-ignored natural law. Failure to properly regulate apoptosis can have catastrophic consequences. Cancer and many diseases (AIDS, Alzheimer’s disease, Parkinson’s disease, heart attack, stroke, etc. ) are thought to arise from deregulation of apoptosis. As apoptosis emerges as a key biological regulatory mechanism, it has become harder and harder to keep up with new developments in this field.
Calcium Binding Protein Protocols
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Author : Hans J. Vogel
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05
Calcium Binding Protein Protocols written by Hans J. Vogel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.
Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on–off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are discussed in detail. H- ever, proteins involved in calcium handling (e. g. , calcium pumps and calcium channels), fall outside of the scope of these two volumes. Also, calcium-bi- ing proteins involved in bone deposition will not be discussed, as this specific topic has been addressed previously. The focus of these two books is on studies of the calcium-binding proteins and their behavior in vitro and in vivo. The primary emphasis is on protein chemistry and biophysical methods. Many of the methods described will also be applicable to proteins that do not bind calcium. Calcium-Binding Protein Protocols is divided into three main sections. The section entitled Introduction and Reviews provides information on the role of calcium in intracellular secondary messenger activation mechanisms. Mo- over, unique aspects of calcium chemistry and the utilization of calcium in dairy proteins, as well as calcium-binding proteins involved in blood clotting, are addressed.
Sol Gel Chemistry Applied To Materials Science
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Author : Michelina Catauro
language : en
Publisher: MDPI
Release Date : 2019-10-14
Sol Gel Chemistry Applied To Materials Science written by Michelina Catauro and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-14 with Science categories.
Sol–gel technology is a contemporary advancement in science that requires taking a multidisciplinary approach with regard to its various applications. This book highlights some applications of the sol–gel technology, including protective coatings, catalysts, piezoelectric devices, wave guides, lenses, high-strength ceramics, superconductors, synthesis of nanoparticles, and insulating materials. In particular, for biotechnological applications, biomolecules or the incorporation of bioactive substances into the sol–gel matrix has been extensively studied and has been a challenge for many researchers. Some sol–gel materials are widely applied in light-emitting diodes, solar cells, sensing, catalysis, integration in photovoltaic devices, and more recently in biosensing, bioimaging, or medical diagnosis; others can be considered excellent drug delivery systems. The goal of an ideal drug delivery system is the prompt delivery of a therapeutic amount of the drug to the proper site in the body, where the desired drug concentration can be maintained. The interactions between drugs and the sol–gel system can affect the release rate. In conclusion, the sol–gel synthesis method offers mixing at the molecular level and is able to improve the chemical homogeneity of the resulting composite. This opens new doors not only regarding compositions of previously unattainable materials, but also to unique structures with different applications.