Polymorphisms

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Genetic Polymorphism And Disease

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Author : Syed Sameer Aga
language : en
Publisher: CRC Press
Release Date : 2022-12-06

Genetic Polymorphism And Disease written by Syed Sameer Aga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Science categories.

Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins. Key Features Describes the genetic polymorphism and its various types Discusses the role of genetic polymorphisms in modulating the risk of various human diseases Explores various molecular techniques used for detecting GPs Characterizes the role of SNPs in modulating the susceptibility of human diseases Provides a genetic basis for individual variations in response to therapeutics

Genetic Polymorphism And Cancer Susceptibility

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Author : Aga Syed Sameer
language : en
Publisher: Springer Nature
Release Date : 2021-04-22

Genetic Polymorphism And Cancer Susceptibility written by Aga Syed Sameer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-22 with Medical categories.

This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

Genetic Polymorphisms

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Author : Narasimha Reddy Parine
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-09-06

Genetic Polymorphisms written by Narasimha Reddy Parine and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-06 with Medical categories.

The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.

Infection Polymorphism And Evolution

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Author : W.D. Hamilton
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Infection Polymorphism And Evolution written by W.D. Hamilton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Resulting from a Royal Society discussion meeting, this volume presents a short review of the topic of parasite-host co-evolution. Current thinking on evolution in parasites, viruses and other pathogens is discussed.

Sepsis

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Author : Simon V. Baudouin
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-02

Sepsis written by Simon V. Baudouin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-02 with Medical categories.

Discover new, effective strategies to prevent and treat sepsis. In this book, leading medical experts consider how the pathways implicated in early and late sepsis interact. Next, the book describes numerous pharmacological approaches that enable you to provide state-of-the-technology care for patients in both early and late sepsis. You’ll also get detailed discussions of how the various physiological systems function under sepsis.

Genetics And Molecular Biology Of Muscle Adaptation

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Author : Neil Spurway
language : en
Publisher: Elsevier Health Sciences
Release Date : 2006-01-01

Genetics And Molecular Biology Of Muscle Adaptation written by Neil Spurway and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Medical categories.

This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.

The Role Of Gene Polymorphism In Modulating The Immune Responses Against Tropical Infectious Diseases

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Author : Adriana Malheiro
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-29

The Role Of Gene Polymorphism In Modulating The Immune Responses Against Tropical Infectious Diseases written by Adriana Malheiro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-29 with Science categories.

Fc Mediated Antibody Functions And Fc Receptor Polymorphism

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Author : Guido Ferrari
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-28

Fc Mediated Antibody Functions And Fc Receptor Polymorphism written by Guido Ferrari and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-28 with categories.

Index Medicus

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Author :
language : en
Publisher:
Release Date : 2004

Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Cumulated Index Medicus

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Author :
language : en
Publisher:
Release Date : 1974

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Medicine categories.