Polyphosphazenes For Biomedical Applications
DOWNLOAD
Download Polyphosphazenes For Biomedical Applications PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Polyphosphazenes For Biomedical Applications book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Polyphosphazenes For Biomedical Applications
DOWNLOAD
Author : K. A. Andrianov
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-28
Polyphosphazenes For Biomedical Applications written by K. A. Andrianov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Science categories.
Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.
Chemistry And Applications Of Polyphosphazenes
DOWNLOAD
Author : Harry R. Allcock
language : en
Publisher: Wiley-Interscience
Release Date : 2002-12-05
Chemistry And Applications Of Polyphosphazenes written by Harry R. Allcock and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-05 with Technology & Engineering categories.
Polyphosphazenes are polymers containing nitrogen as part of their backbone; they are commonly used in O-rings, pipelines, and seals in oil, fuel delivery, and storage systems. New polyphosphazene derivatives have been proven biocompatible, biodegradable, and bioactive, and some of them are being investigated for possible medical applications. Harry Allcock’s Chemistry and Applications of Polyphosphazenes provides the only published compilation of material on polyphosphazenes, detailing synthetic methodologies and physical properties for each substance. Allcock explains the critical relationships between structure and properties, aiding the practicing researcher in the design of polyphosphazenes with specific applications. Professionals and students in polymer science, engineering, and industries such as rubbers and plastics will find Chemistry and Applications of Polyphosphazenes to be an invaluable text.
Natural And Synthetic Biomedical Polymers
DOWNLOAD
Author : Sangamesh G. Kum bar
language : en
Publisher: Newnes
Release Date : 2014-01-21
Natural And Synthetic Biomedical Polymers written by Sangamesh G. Kum bar and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-21 with Technology & Engineering categories.
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Polyphosphazenes For Medical Applications
DOWNLOAD
Author : Ian Teasdale
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-09-07
Polyphosphazenes For Medical Applications written by Ian Teasdale and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Technology & Engineering categories.
This book describes preparation techniques for well-defined, customizable poly(organo)phosphazene materials and their applications in nanomedicine, i.e. as macromolecular carriers for drug delivery, immunology, gene therapy, or tissue regeneration. This 2nd edition of Polyphosphazenes for Medical Applications has been updated and extended for researchers in the field as well as those considering using polyphosphazenes for a specific application.
Organic Polymers
DOWNLOAD
Author : Arpit Sand
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-11
Organic Polymers written by Arpit Sand and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with Science categories.
This book, Organic Polymers, covers aspects that are of immediate concern to a new entrant to the field of polymers. Taken as a whole, these eight chapters aim to help the readers easily assimilate other specialized and exhaustive treatises on the subject. Topics dealing with the chemistry and technology of polymers are presented in a careful and logical manner so as to provide an easy and enjoyable read. Several examples and analogies are included so to make the main concepts easy to follow and tables and figures are included so that the book can serve, to a limited extent, as a hand book dealing with polysaccharides with different parameters. This book is meant for students studying polysaccharides and those working on graft copolymers and other allied polymer industries but without a formal educational background in organic polymers.
Polyphosphazenes For Medical Applications
DOWNLOAD
Author : Ian Teasdale
language : en
Publisher: Smithers Rapra
Release Date : 2014-11-03
Polyphosphazenes For Medical Applications written by Ian Teasdale and has been published by Smithers Rapra this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-03 with Medical categories.
Polyphosphazenes are a unique family of inorganic polymers with an unparalleled broad spectrumof properties. Furthermore, these properties can be easily fine-tuned by organic side-group substituents to give poly(organo)phosphazenes with precisely desired characteristics making them valuable tools to prepare multifunctional, advanced materials for biomedical applications. Bioerodible poly(organo)phosphazenes are of particular interest and with suitable organic substituents their rate of degradation can be tailored to give materials ranging from highly biostable to rapidly hydrolysable, with proven biocompatibility and nontoxic products. This book provides an overview of the current state of development of poly(organo)phosphazenes designed specifically for use in medical applications. The objective is firstly to provide detailed information on the latest preparation techniques to synthesise well-defined, customised materials for the desired application. Secondly, a detailed review of the most recent data for application studies in medicine is provided, with particular focus given to their applications as macromolecular carriers innanomedicine, including drug delivery, immunology and gene therapy, as well as their use as degradable scaffolds for tissue regeneration. This book should not only provide a valuable and critical summary for researchers already working in, or looking to enter the field, but also those contemplating the use of polyphosphazenes for their desired application.
Advanced Biomaterials In Biomedical Engineering And Drug Delivery Systems
DOWNLOAD
Author : Naoya Ogata
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Advanced Biomaterials In Biomedical Engineering And Drug Delivery Systems written by Naoya Ogata and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.
Smart Inorganic Polymers
DOWNLOAD
Author : Evamarie Hey-Hawkins
language : en
Publisher: John Wiley & Sons
Release Date : 2019-02-06
Smart Inorganic Polymers written by Evamarie Hey-Hawkins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with Technology & Engineering categories.
Provides complete and undiluted knowledge on making inorganic polymers functional. This comprehensive book reflects the state of the art in the field of inorganic polymers, based on research conducted by a number of internationally leading research groups working in this area. It covers the synthesis aspects of synthetic inorganic polymers and looks at multiple inorganic monomers as building blocks, which exhibit unprecedented electronic, redox, photo-emissive, magnetic, self-healing and catalytic properties. It also looks at the applications of inorganic polymers in areas such as optoelectronics, energy storage, industrial chemistry, and biology. Beginning with an overview of the use of smart inorganic polymers in daily life, Smart Inorganic Polymers: Synthesis, Properties and Emerging Applications in Materials and Life Sciences goes on to study the synthesis, properties, and applications of polymers incorporating different heteroelements such as boron, phosphorus, silicon, germanium, and tin. The book also examines inorganic polymers in flame-retardants, as functional materials, and in biology. An excellent addition to the polymer scientists' and synthetic chemists' toolbox Summarizes the state of the art on how to make and use functional inorganic polymers, from synthesis to applications Edited by the coordinator of a highly funded European community research program (COST action) that focuses specifically on the exploration of inorganic polymers Features contributions from top experts in the field Aimed at academics and industrial researchers in this field, Smart Inorganic Polymers: Synthesis, Properties and Emerging Applications in Materials and Life Sciences will also benefit scientists who want to get a better overview on the state-of-the-art of this rapidly advancing area.
A Handbook Of Applied Biopolymer Technology
DOWNLOAD
Author : Sanjay Kumar Sharma
language : en
Publisher: Royal Society of Chemistry
Release Date : 2011
A Handbook Of Applied Biopolymer Technology written by Sanjay Kumar Sharma and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
This handbook covers the latest research in green chemistry principles for new, environmentally friendly processes in the fields of engineering, science, and technology.
Computational Chemistry And Molecular Modeling Of Polyphosphazenes For Biomedical Applications
DOWNLOAD
Author : Jessica Kroger
language : en
Publisher:
Release Date : 2012
Computational Chemistry And Molecular Modeling Of Polyphosphazenes For Biomedical Applications written by Jessica Kroger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Polyphosphazenes are a unique class of polymers whose properties are attractive for a variety of biomedical applications. Consisting of a backbone of alternating phosphorus and nitrogen atoms with organic side groups attached to the phosphorus, polyphosphazenes are specifically advantageous for drug delivery which can exploit the backbone's sensitivity to hydrolytic degradation. Unfortunately, characteristic data of these polymers and the mechanisms driving hydrolysis are limited in the literature. In this study, computational chemistry and molecular modeling were used to investigate polyphosphazenes from a theoretical perspective. Properties of four biomedically relevant polyphosphazenes poly(dichlorophosphazene) (PDCP), poly(glycineethylesterphosphazene) (PGEEP), poly[bis(carboxylatophenoxy)phosphazene] (PCPP) and poly[di(imidazole)phosphazene] (PDIP) were investigated by molecular dynamics simulations. The densities obtained for these polymers ranged from 1.269 (PGEEP) to 2.174 (crystalline PDCP) g/cm3. As validation of the simulation results, the glass transition temperature of PGEEP was estimated to be 255 K, in agreement with experimental results. Radial distribution functions showed evidence of hydrogen bonding in amorphous PCPP, but little or no hydrogen bonding was observed in the remaining polymers. Hydrogen bonding leads to increased electrostatic interactions in amorphous PCPP, as evidenced by the largersolubility parameter of 19.082 (J/cm3)1/2 obtained for PCPP compared to 14.437, 13.928, and 14.647 (J/cm3)1/2 for amorphous PDCP, PGEEP and PDIP, respectively. Time-correlation functions were calculated for each polymer to determine the relative flexibility of the backbones and side-groups of each polyphosphazene. The backbones and side-groups of both amorphous PDCP and PGEEP show significant flexibility while those of amorphous PCPP and PDIP show more limited motions. Density functional theory (DFT) calculations, including the ab initio molecular dynamics method, atom-centered density matrix propagation (ADMP), were used to investigate the hydrolysis reaction of a dichlorophosphazene (DCP) trimer. The model trimer, intermediate structures and the product of the first step of hydrolysis, were optimized using density functional theory (DFT) with the B3LYP density functional, followed by a 600 fs ADMP simulation. Natural bond order analysis (NBO) was used to determine atomic charges and electron occupancy of the bond orbitals and the lone pair orbitals of the molecule at various points along the simulation pathway. The simulation successfully shows dissociation of the trimer backbone into two distinct product molecules, shown through both increasing separation of the product units and through the more thorough NBO analysis of the bond orbitals.