Polyphosphazenes For Medical Applications
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Polyphosphazenes For Medical Applications
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Author : Ian Teasdale
language : en
Publisher: Smithers Rapra
Release Date : 2014-11-03
Polyphosphazenes For Medical Applications written by Ian Teasdale and has been published by Smithers Rapra this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-03 with Medical categories.
Polyphosphazenes are a unique family of inorganic polymers with an unparalleled broad spectrumof properties. Furthermore, these properties can be easily fine-tuned by organic side-group substituents to give poly(organo)phosphazenes with precisely desired characteristics making them valuable tools to prepare multifunctional, advanced materials for biomedical applications. Bioerodible poly(organo)phosphazenes are of particular interest and with suitable organic substituents their rate of degradation can be tailored to give materials ranging from highly biostable to rapidly hydrolysable, with proven biocompatibility and nontoxic products. This book provides an overview of the current state of development of poly(organo)phosphazenes designed specifically for use in medical applications. The objective is firstly to provide detailed information on the latest preparation techniques to synthesise well-defined, customised materials for the desired application. Secondly, a detailed review of the most recent data for application studies in medicine is provided, with particular focus given to their applications as macromolecular carriers innanomedicine, including drug delivery, immunology and gene therapy, as well as their use as degradable scaffolds for tissue regeneration. This book should not only provide a valuable and critical summary for researchers already working in, or looking to enter the field, but also those contemplating the use of polyphosphazenes for their desired application.
Polyphosphazenes For Medical Applications
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Author : Ian Teasdale
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-09-07
Polyphosphazenes For Medical Applications written by Ian Teasdale and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Technology & Engineering categories.
This book describes preparation techniques for well-defined, customizable poly(organo)phosphazene materials and their applications in nanomedicine, i.e. as macromolecular carriers for drug delivery, immunology, gene therapy, or tissue regeneration. This 2nd edition of Polyphosphazenes for Medical Applications has been updated and extended for researchers in the field as well as those considering using polyphosphazenes for a specific application.
Polyphosphazenes For Biomedical Applications
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Author : K. A. Andrianov
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-28
Polyphosphazenes For Biomedical Applications written by K. A. Andrianov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Science categories.
Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.
Polyphosphazenes For Medical Applications
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Author : IAN. TEASDALE
language : en
Publisher:
Release Date : 2020-08-24
Polyphosphazenes For Medical Applications written by IAN. TEASDALE and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with categories.
This book describes preparation techniques for well-defined, customizable poly(organo)phosphazene materials and their applications in nanomedicine, i.e. as macromolecular carriers for drug delivery, immunology, gene therapy, or tissue regeneration. This 2nd edition of Polyphosphazenes for Medical Applications has been updated and extended for researchers in the field as well as those considering using polyphosphazenes for a specific application.
Natural And Synthetic Biomedical Polymers
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Author : Sangamesh G. Kum bar
language : en
Publisher: Newnes
Release Date : 2014-01-21
Natural And Synthetic Biomedical Polymers written by Sangamesh G. Kum bar and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-21 with Technology & Engineering categories.
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Durability And Reliability Of Medical Polymers
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Author : Mike Jenkins
language : en
Publisher: Elsevier
Release Date : 2012-08-13
Durability And Reliability Of Medical Polymers written by Mike Jenkins and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-13 with Medical categories.
Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers.Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians. - Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers - Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers - Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body
An Introduction To Biomaterials Second Edition
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Author : Jeffrey O. Hollinger
language : en
Publisher: CRC Press
Release Date : 2011-11-28
An Introduction To Biomaterials Second Edition written by Jeffrey O. Hollinger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-28 with Medical categories.
A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Zheng Zhang
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Zheng Zhang and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Kayvon Modjarrad
language : en
Publisher: Elsevier
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Kayvon Modjarrad and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Medical categories.
While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they're creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. - Gathers discussions of a large number of applications of polymers in medicine in one place - Provides an insight into both the legal and clinical implications of device design - Relevant to industry, academic and medical professionals - Presents the latest developments in the field, including medical devices on a nano-scale
New Polymeric Materials Based On Element Blocks
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Author : Yoshiki Chujo
language : en
Publisher: Springer
Release Date : 2018-12-22
New Polymeric Materials Based On Element Blocks written by Yoshiki Chujo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-22 with Technology & Engineering categories.
This book introduces the recent progress that has resulted from utilizing the idea of "element-block polymers". A structural unit consisting of various groups of elements is called an "element-block." The design and synthesis of new element-blocks, polymerization of these blocks, and development of methods of forming higher-order structures and achieving hierarchical interface control in order to yield the desired functions are expected to result in manifold advantages. These benefits will encourage the creation of new polymeric materials that share, at a high level, electronic, optical, and magnetic properties not achievable with conventional organic polymeric materials as well as forming properties of molding processability and flexible designability that inorganic materials lack. By pioneering innovative synthetic processes that exploit the reactivity of elements and the preparation techniques employed for inorganic element-blocks, the aim is (1) to create a new series of innovative polymers based on the novel concept of element-block polymers, in which the characteristics of elements are extensively combined and utilized, and (2) to formulate theories related to these polymers. This book demonstrates especially the design strategies and the resulting successful examples offering highly functional materials that utilize element-block polymers as a key unit.