Poxviruses

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Poxviruses

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Author : Andrew Mercer
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-15

Poxviruses written by Andrew Mercer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-15 with Medical categories.

This monograph provides a comprehensive review of the poxvirus family with a particular emphasis on current developments. It includes the latest insights into poxviral molecular biology, diagnosis, therapy, vaccine development and the beneficial exploitation of these viruses in biomedical research. Each chapter is written by a leader in the field, and the book includes historical perspectives and summaries of recent advances in the field.

Biology Of Poxviruses

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Author : Samuel Dales
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08

Biology Of Poxviruses written by Samuel Dales and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.

This volume, Biology of Poxviruses, marks our debut as editors of this well known series. We plan to continue the tradition of providing a forum for exten sive, critical reviews of individual virus groups, as exemplified by the present volume. But the pace of discovery is accelerating so rapidly that we feel the need to offer an additional format: volumes that contain collections of shorter, topical reviews on a group of related subjects. Such collections might cut across con ventional boundaries between virus groups, dealing, as an example, with a partic ular aspect of virus-cell interaction. Admittedly, this new format stretches the term "monograph" beyond the accepted definition, but we believe that we should pay that price to maintain the usefulness of the series as a medium of scientific communication. Whenever possible, we will enlist the aid of deputy editors to bring such col lections to fruition. As in the past, the editors and the publisher will welcome suggestions for topics and contributions.

Recombinant Poxviruses

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Author : Matthew M. Binns
language : en
Publisher: CRC Press
Release Date : 1992-05-27

Recombinant Poxviruses written by Matthew M. Binns and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-05-27 with Science categories.

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for revaccination. The opening chapter describes the origin of vaccinia virus, its use to eradicate smallpox, and the pathogenesis of poxvirus infections. Subsequent chapters examine the molecular biology of poxviruses, methods of constructing vaccinia virus recombinants, and applications; the use and immune responses induced by poxvirus recombinants as live vaccines; and the important issues of the safety and immunogenicity of vaccinia virus. The book's final two chapters report the progress that has been made developing avipoxviruses and parapoxviruses as candidate recombinant vaccines. Recombinant Poxviruses will be a welcome addition to the bookshelves of virologists, microbiologists, infectious disease specialists, and veterinarians.

Vaccinia Virus And Poxvirology

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Author : Stuart N. Isaacs
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03

Vaccinia Virus And Poxvirology written by Stuart N. Isaacs and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.

The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner’s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now extinct or rare in nature (2). Recent genome sequencing studies confirm the distinctness of variola virus, cowpox virus, and vaccinia virus and also their very close genetic relationship, which accounts for the cross protection of smallpox vaccines. The novelty of the smallpox vaccine can be readily appreciated by the time it took, about 80 years, before the next live vaccine against rabies was developed, and another 50 years for the yellow fever vaccine. Moreover, the eradication of smallpox in 1977 stands as a unique medical achievement. Because of its historical role, sma- pox vaccination contributed greatly to present concepts of infectious disease, immunity, and pathogenesis. Less well known, however, are the many other “firsts” for vaccinia virus.

The Orthopoxviruses

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Author : Frank Fenner
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Orthopoxviruses written by Frank Fenner and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.

The Orthopoxviruses presents knowledge and comprehensive and integrated picture of orthopoxviruses. The book looks into the molecular biology of this genusof viruses, particularly, the structure and chemical composition of the virion, replication, morphogenesis, pathogenesis, pathology, and immunology of this virus’ infections. It also elucidates the global spread, control, and eradication of smallpox. Additionally, the book describes a potentially important use of vaccinia virus, namely, its use as a vector for genes from other viruses, bacteria, or protozoa that specify antigens important in stimulating the production of a protective immune response. Such comprehensive account of all aspects of the biology of all known species of orthopoxviruses will be valuable to molecular biologists, virologists, immunologists, pathologists, and researchers in the veterinary sciences.

Vaccinia Virus

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Author : Jason Mercer
language : en
Publisher:
Release Date : 2019

Vaccinia Virus written by Jason Mercer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical virology categories.

This detailed book provides practical information for the laboratory that can be applied to the study of vaccinia and other poxviruses while emphasizing long-standing field standards and focusing on emerging new technologies applied in the field of poxvirology. The methods and protocols have been designed with the bench scientist in mind, being presented in a fashion that makes them useful for both starting and veteran poxvirus researchers. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Vaccinia Virus: Methods and Protocols serves as a valuable resource for scientists looking to bring new methods and procedures into their lab in order to make exciting discoveries that will continue to deepen our understanding of this fascinating virus family.

Orthopoxviruses Pathogenic For Humans

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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-09

Orthopoxviruses Pathogenic For Humans written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-09 with Medical categories.

Orthopoxviruses Pathogenic for Humans covers those viruses capable of causing disease in man, including monkeypox, smallpox, cowpox, and vaccinia. The coverage of each virus is comprehensive, covering the biology, molecular biology, and ecology of the virus as well as the clinical and epidemiological aspects of these viruses in humans and animals. In addition, this volume highlights developments in genetic engineering that are paving the way for potential therapeutic treatments of these viruses.

Cultivation And Immunological Studies On Pox Group Of Viruses With Special Reference To Buffalo Pox Virus

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Author :
language : en
Publisher:
Release Date : 1987

Cultivation And Immunological Studies On Pox Group Of Viruses With Special Reference To Buffalo Pox Virus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Buffalopox virus categories.

Cultivation And Immunological Studies On Pox Group Of Viruses With Special Reference To Buffalo Pox Virus

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Author : Thankam Mathew
language : en
Publisher:
Release Date : 1987

Cultivation And Immunological Studies On Pox Group Of Viruses With Special Reference To Buffalo Pox Virus written by Thankam Mathew and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.

Therapeutic Intervention For Poxviruses

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Author : Sharon E. Altmann
language : en
Publisher:
Release Date : 2009

Therapeutic Intervention For Poxviruses written by Sharon E. Altmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.