Precision Medicine In Neurodegenerative Disorders
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Precision Medicine In Neurodegenerative Disorders
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-02-14
Precision Medicine In Neurodegenerative Disorders written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-14 with Medical categories.
Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. - Summarizes theory and research on precision medicine in neurodegenerative disorders - Covers basic biology, clinical trials and therapeutics - Includes disease mechanisms, genetic subtypes, and more
Precision Medicine In Neurodegenerative Disorders
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-02-16
Precision Medicine In Neurodegenerative Disorders written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-16 with Medical categories.
Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes. - Summarizes theory and research on precision medicine in neurodegenerative disorders - Covers basic biology, clinical trials and therapeutics - Includes disease mechanisms, genetic subtypes, and more
Personalised Medicine
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Author : Sherif El-Khamisy
language : en
Publisher: Springer
Release Date : 2017-08-24
Personalised Medicine written by Sherif El-Khamisy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-24 with Medical categories.
The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combat degenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine.
Precision Medicine
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Author : Hans-Peter Deigner
language : en
Publisher: Academic Press
Release Date : 2018-02-15
Precision Medicine written by Hans-Peter Deigner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-15 with Medical categories.
Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. - Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods - Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation - Encompasses easy access to relevant approaches, interactions and original literature
Molecular Medicine And Biomedical Research In The Era Of Precision Medicine
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Author : Ranbir Chander Sobti
language : en
Publisher: Elsevier
Release Date : 2025-05-15
Molecular Medicine And Biomedical Research In The Era Of Precision Medicine written by Ranbir Chander Sobti and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-15 with Science categories.
Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. The book delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions. It covers a range of technologies, including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases.The book also tackles targeted treatments of different disease types, including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered, providing an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, and acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences. - Investigates the molecular basis and mechanisms of diseases, including cardiovascular, infectious, and neurological diseases - Presents molecular-based therapeutics for personalized treatment and the diagnosis of various conditions - Considers a range of technologies in the field of biomedicine and molecular medicine, including artificial intelligence and nanotechnology
Molecular Medicine
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Author : Sinem Nalbantoglu
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-11-06
Molecular Medicine written by Sinem Nalbantoglu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.
Innovations In Precision Medicine And Genomics
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Author : Koumpouros, Yiannis
language : en
Publisher: IGI Global
Release Date : 2025-06-06
Innovations In Precision Medicine And Genomics written by Koumpouros, Yiannis and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-06 with Science categories.
Innovations in precision medicine and genomics revolutionize healthcare by enabling more personalized and targeted treatments for individuals based on their unique genetic makeup. Advances in genomic sequencing technologies lower the cost and time required to decode the human genome, making genetic information more accessible to clinicians and researchers. This improves precision medicine, where treatments are tailored to a patient's genetic profile, optimizing efficacy and minimizing side effects. With these innovations, challenges persist, including issues related to data privacy, ethical use of genetic information, and the need for equitable access to cutting-edge treatments. As the field evolves, precision medicine may transform personalized healthcare, improving outcomes and quality of life for patients. Innovations in Precision Medicine and Genomics provides a comprehensive overview of the latest advancements, applications, and implications of digital health technologies across various domains. It offers insights into emerging trends, best practices, and future directions in digital health. This book covers topics such as drug delivery, nanotechnology, and pharmaceutics, and is a useful resource for business owners, medical and healthcare professionals, biologists, academicians, researchers, and scientists.
Precision Medicine Recent Advances Current Challenges And Future Perspectives
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Author : Oriana Awwad
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-18
Precision Medicine Recent Advances Current Challenges And Future Perspectives written by Oriana Awwad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.
Personalized medicine (precision medicine) is an evolving field that comprises medical interventions tailored to individuals or groups of patients. It is designed to facilitate enhanced screening and earlier disease detection, more precise disease diagnosis, and improved treatment. Personalized medicine allows patients to receive specific therapies that work best for them aiming for more effective treatment, better outcomes, safer clinical managements and more efficient health systems.
The Spectrum Of Hope
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Author : Gayatri Devi
language : en
Publisher: Hachette+ORM
Release Date : 2017-10-31
The Spectrum Of Hope written by Gayatri Devi and has been published by Hachette+ORM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-31 with Health & Fitness categories.
Imagine finding a glimmer of good news in a diagnosis of Alzheimer’s. And imagine how that would change the outlook of the 5 million Americans who suffer from Alzheimer’s disease and other dementias, not to mention their families, loved ones, and caretakers. A neurologist who’s been specializing in dementia and memory loss for more than 20 years, Dr. Gayatri Devi rewrites the story of Alzheimer’s by defining it as a spectrum disorder—like autism, Alzheimer’s is a disease that affects different people differently. She encourages people who are worried about memory impairment to seek a diagnosis, because early treatment will enable doctors and caregivers to manage the disease more effectively through drugs and other therapies. Told through the stories of Dr. Devi’s patients, The Spectrum of Hope humanizes the science, and offers equal parts practical advice and wisdom with skillful ease, along with real hope. Here are chapters on how to maintain independence and dignity; how to fight depression, anxiety, and apathy; how to communicate effectively with a person suffering from dementia. Plus chapters on sexuality, genetics, going public with the diagnosis, even putting together a bucket list—because through her practice, Dr. Devi knows that the majority of Alzheimer’s patients continue to live and work in their communities. They babysit their grandkids, drive to the store (or own the store), serve their clients, or otherwise live fulfilling lives. That’s news that 5 million people are waiting to hear.
The Era Of Precision Medicine Genetics Pharmacy And Personalized Health
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
The Era Of Precision Medicine Genetics Pharmacy And Personalized Health written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Health & Fitness categories.
This book explores the fascinating field of precision medicine and its role in understanding and treating genetic diseases in various systems and organs of the human body. Throughout the chapters, topics such as precision medicine in the context of developmental diseases, nutrigenomics and its relationship to diet personalization, pulmonary diseases, musculoskeletal diseases, genetic diseases of the cardiovascular system, and genetic diseases of the hepatic system are explored. In addition, subjects such as the application of genetic tests in precision medicine, analysis of genetic variants, precision medicine in women's health, rare genetic diseases, dermatological diseases, nervous system diseases, renal system diseases and metabolism diseases are addressed. . The book also explores the role of epigenetics in precision medicine, highlighting how modifications to the genetic environment can influence disease development and progression. In addition, topics such as allergic diseases, genetic diseases of the respiratory system and genetic diseases of the musculoskeletal system are discussed. As a comprehensive guide, this book provides valuable insights into precision medicine and its impact on clinical practice in the quest for more accurate diagnoses and personalized treatments. It is essential reading for healthcare professionals, researchers, and students interested in the field of medical genetics and its applications in the era of precision medicine.