Precision Molecular Pathology Of Glioblastoma


Precision Molecular Pathology Of Glioblastoma
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Precision Molecular Pathology Of Glioblastoma


Precision Molecular Pathology Of Glioblastoma
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Author : José Javier Otero
language : en
Publisher: Springer Nature
Release Date : 2021-04-30

Precision Molecular Pathology Of Glioblastoma written by José Javier Otero and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-30 with Medical categories.


This volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.



Precision Molecular Pathology Of Neoplastic Pediatric Diseases


Precision Molecular Pathology Of Neoplastic Pediatric Diseases
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Author : Larissa V. Furtado
language : en
Publisher: Springer
Release Date : 2018-08-01

Precision Molecular Pathology Of Neoplastic Pediatric Diseases written by Larissa V. Furtado and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-01 with Medical categories.


This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care. Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.



Precision Molecular Pathology Of Aggressive B Cell Lymphomas


Precision Molecular Pathology Of Aggressive B Cell Lymphomas
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Author : Genevieve M. Crane
language : en
Publisher: Springer Nature
Release Date :

Precision Molecular Pathology Of Aggressive B Cell Lymphomas written by Genevieve M. Crane and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Precision Molecular Pathology Of Myeloid Neoplasms


Precision Molecular Pathology Of Myeloid Neoplasms
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Author : Chung-Che (Jeff) Chang
language : en
Publisher: Springer
Release Date : 2018-08-26

Precision Molecular Pathology Of Myeloid Neoplasms written by Chung-Che (Jeff) Chang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-26 with Medical categories.


This volume provides a comprehensive, state-of-the art review of myeloid neoplasms. The book presents updated information on epidemiology, clinical presentation, morphologic findings, molecular genomic abnormalities, pathogenesis, and target therapies. The text helps to guide accurate diagnosis, the administration of appropriate ancillary molecular tests, patient management, and investigative efforts. The book also includes over 200 illustrations, photographs, and tables. Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.



Glioblastoma Resistance To Chemotherapy Molecular Mechanisms And Innovative Reversal Strategies


Glioblastoma Resistance To Chemotherapy Molecular Mechanisms And Innovative Reversal Strategies
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Author : Ramasamy Paulmurugan
language : en
Publisher: Academic Press
Release Date : 2021-06-25

Glioblastoma Resistance To Chemotherapy Molecular Mechanisms And Innovative Reversal Strategies written by Ramasamy Paulmurugan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-25 with Science categories.


Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance



Precision Molecular Pathology Of Lung Cancer


Precision Molecular Pathology Of Lung Cancer
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Author : Philip T. Cagle
language : en
Publisher: Springer
Release Date : 2017-11-10

Precision Molecular Pathology Of Lung Cancer written by Philip T. Cagle and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-10 with Medical categories.


This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions. Authored by experts in the field, Precision Molecular Pathology of Lung Cancer, Second Edition remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.



Precision Molecular Pathology Of Liver Cancer


Precision Molecular Pathology Of Liver Cancer
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Author : Chen Liu
language : en
Publisher: Springer
Release Date : 2018-01-09

Precision Molecular Pathology Of Liver Cancer written by Chen Liu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-09 with Medical categories.


This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.



Precision Molecular Pathology Of Myeloid Neoplasms


Precision Molecular Pathology Of Myeloid Neoplasms
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Author : Chung-Che (Jeff) Chang
language : en
Publisher: Springer
Release Date : 2017-09-25

Precision Molecular Pathology Of Myeloid Neoplasms written by Chung-Che (Jeff) Chang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-25 with Medical categories.


This volume provides a comprehensive, state-of-the art review of myeloid neoplasms. The book presents updated information on epidemiology, clinical presentation, morphologic findings, molecular genomic abnormalities, pathogenesis, and target therapies. The text helps to guide accurate diagnosis, the administration of appropriate ancillary molecular tests, patient management, and investigative efforts. The book also includes over 200 illustrations, photographs, and tables. Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.



Precision Molecular Pathology Of Bladder Cancer


Precision Molecular Pathology Of Bladder Cancer
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Author : Donna E. Hansel
language : en
Publisher: Springer
Release Date : 2018-01-05

Precision Molecular Pathology Of Bladder Cancer written by Donna E. Hansel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-05 with Medical categories.


This succinct yet comprehensive volume describes current and emerging concepts in molecular pathology of bladder cancer. Divided into two distinct sections, the first part focuses on the general principles of molecular findings in bladder cancer, while the second part focuses on the molecular changes associated with specific histologic subtypes. The volume also addresses such topics as molecular alterations in non-invasive and invasive disease, including bladder cancer variants as appropriate, emerging molecular classifiers of bladder cancer, and molecular associations to outcome and treatment. Written by experts in the field, Precision Molecular Pathology of Bladder Cancer is a valuable resource for those in the urologic community, including urologic pathologists, urologists, urologic oncologists and radiation oncologists, who treat and manage bladder cancer.



Precision Molecular Pathology Of Prostate Cancer


Precision Molecular Pathology Of Prostate Cancer
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Author : Brian D. Robinson
language : en
Publisher: Springer
Release Date : 2018-02-13

Precision Molecular Pathology Of Prostate Cancer written by Brian D. Robinson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-13 with Medical categories.


This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) and Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.