Prevention Of Progression In Chronic Liver Disease
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Prevention Of Progression In Chronic Liver Disease
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Author : N. Hiyashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-07-21
Prevention Of Progression In Chronic Liver Disease written by N. Hiyashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-21 with Medical categories.
In several liver diseases, the underlying cause cannot always be eliminated, i.e. the progression of liver disease cannot be prevented. This is particularly true for non-responders to the treatment of chronic hepatitis C (HCV). It is relevant for more than 40% of patients with HCV genotype 1 and up to 20% of patients with genotype 2 or 3. Several approaches are now underway to prevent or ameliorate mechanisms of disease progression. In Asia, and particularly in Japan, Glycyrrhizine-SNMC has been widely used for this purpose. At present, SNMC is under clinical evaluation in Europe. This book, the proceedings of the Falk Workshop on 'Prevention of Progression in Chronic Liver Disease - An Update on SNMC (Stronger Neo-Minophagen C)' (Part IV of the XII Falk Liver Week, in honour of Hans Popper's 100th birthday) held in Freiburg, Germany, on 22 October 2003, is devoted to the understanding of basic mechanisms of fibrogenesis, the state of the art of non-invasive markers of disease progression that may substitute liver biopsy in the future, and of other predictive parameters indicating disease progression, in particular the development of hepatocellular carcinoma. All these problems are particularly relevant for chronic hepatitis C. A better characterization of so-called non-responders for the treatments available is crucial for the development of new strategies preventing or postponing disease progression. Such strategies should influence fibrogenesis and, thus, cirrhosis formation as well as the development of life threatening complications of liver cirrhosis, including hepatocellular carcinoma. In this volume, the available information on SNMC as an approach to prevent progression of chronic liver disease is discussed by several internationally renowned authors who report on the mechanisms of liver fibrogenesis and fibrolysis, on non-invasive markers of disease progression, and on hepatocellular carcinoma as one of the major complications of liver cirrhosis nowadays. Finally, experts from Japan report on their knowledge and experience concerning the drug SNMC/Glycyrrhizine in the prevention of cirrhosis and HCC, and first study results from Europe are presented.
Prevention Measures For Cirrhosis Of Liver And Its Progression
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Author : Sharad C Shah
language : en
Publisher: JP Medical Ltd
Release Date : 2016-10-31
Prevention Measures For Cirrhosis Of Liver And Its Progression written by Sharad C Shah and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-31 with Medical categories.
This book is a concise guide to the prevention and management of cirrhosis of the liver. Divided into four sections, the book begins with an overview of the condition, followed by detailed discussion on the different levels of prevention, both major and minor. The third section examines aetiologies and their prevention and the final chapter covers fibrosis (scarring) reversal. This practical guide provides clinicians and trainees with evidence-based direction on the diagnosis, treatment and management of cirrhosis and its many complications. Key Points Concise guide to prevention and management of liver cirrhosis Provides detail on different levels of prevention Covers fibrosis (scarring) reversal Offers evidence-based direction on diagnosis, treatment and management of cirrhosis and its complications
Liver Cirrhosis And Its Development
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Author : J.L. Boyer
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-03-31
Liver Cirrhosis And Its Development written by J.L. Boyer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-31 with Medical categories.
Liver cirrhosis is a major clinical problem worldwide and is associated with significant morbidity and mortality from its complications, such as liver cell insufficiency with coagulopathy and hepatic encephalopathy, portal hypertension with ascites and gastrointestinal bleeding, hepatorenal syndrome, HCC development and others. This volume, the proceedings of Falk Symposium 115 held in Basel, Switzerland, October 22-24, 1999 (Part II of the Basel Liver Week 1999; XI International Congress of Liver Diseases) covers our present knowledge of the aetiologies and early stages of liver cirrhosis development. Based on this information, strategies are discussed that are aimed at the prevention, early diagnosis and therapy of chronic liver diseases, thus preventing their progression to cirrhosis and its complications, including HCC development. The main topics mentioned above are complemented by three state-of-the-art chapters on modern aspects of medicine in general and hepatology in particular as well as their perspectives beyond the year 2000: `Molecular Medicine', `New Hepatitis Viruses' and `Genetic Liver Diseases: Diagnosis and Therapy'. Introductory chapters focusing on the more basic aspects of the biology of live cells as well as on the mechanisms underlying fibrogenesis, cholestasis and inflammation will be followed by a detailed discussion of the clinically most important causes of liver cirrhosis worldwide: hepatitis viruses B, C and D; toxins (alcohol, drugs and others) as well as metabolic liver diseases (haemochromatosis, Wilson disease, alpha-1-antitrypsin deficiency, porphyria cutanea tarda and protoporphyria). This book, therefore, will interest clinically oriented basic scientists as well as those in clinical practice, givng an update on many aspects of modern hepatology and its perspectives in the next millennium.
Disease Progression And Disease Prevention In Hepatology And Gastroenterology
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Author : P.R. Galle
language : en
Publisher:
Release Date : 2006-06-19
Disease Progression And Disease Prevention In Hepatology And Gastroenterology written by P.R. Galle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-19 with Medical categories.
Here are the proceedings of the Falk Symposium 150, "Disease Progression and Disease Prevention in the Gastrointestinal Tract", held in Berlin, Germany, October, 2005. Pathogenic processes are described as well as primary and secondary prevention and treatment of disease. The symposium generated new perspectives on the various different pathogenic mechanisms in gastrointestinal organs. The book summarizes the state of the art in these different disease entities, as presented at the meeting.
The Evolving Landscape Of Liver Cirrhosis Management
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Author : Hitoshi Yoshiji
language : en
Publisher: Springer Nature
Release Date : 2019-08-29
The Evolving Landscape Of Liver Cirrhosis Management written by Hitoshi Yoshiji and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-29 with Medical categories.
This book comprehensively covers the latest developments in the diagnosis and treatment of liver cirrhosis, including molecular mechanisms and therapeutic strategies. It elaborates on and explores the relation between chronic liver disease (CLD) and its causes, including viral hepatitis, steatohepatitis, autoimmune liver diseases and/or inherited liver diseases, and sustained liver injury. Furthermore, it discusses various complications such as hepatic encephalopathy, ascites, sarcopenia, esophagogastric varices, muscle cramps and pruritus, and the fact that it frequently leads to the development of hepatocellular carcinoma. CLD is becoming a growing issue with substantial effects on public health, and Evolving Landscape in Management of Liver Cirrhosis provides scholars in gastroenterology and hepatology with invaluable insights. At the same time, it is a valuable resource for clinicians specializing in gastroenterology and hepatology as well as for researchers who are curious about new research on liver disease.
Guidelines For The Prevention Care And Treatment Of Persons With Chronic Hepatitis B Virus Infection
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Author : WHO.
language : en
Publisher:
Release Date : 2015
Guidelines For The Prevention Care And Treatment Of Persons With Chronic Hepatitis B Virus Infection written by WHO. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Chronic diseases categories.
These are the first World Health Organization (WHO) guidelines for theprevention care and treatment of persons living with CHB infection andcomplement similar recent published guidance by WHO on the prevention care and treatment of infection due to the hepatitis C virus (HCV). In contrastto several recent international guidelines on the management of CHB infectionfrom the United States Europe Asia-Pacific and the United Kingdom (UK) theprimary audience for these WHO guidelines is country programme managers inall settings but particularly in LMICs to help plan the development and scale up.
Guidelines For The Prevention Care And Treatment Of Persons With Chronic Hepatitis B Infection
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2015-08-05
Guidelines For The Prevention Care And Treatment Of Persons With Chronic Hepatitis B Infection written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-05 with Medical categories.
These are the first World Health Organization (WHO) guidelines for the prevention care and treatment of persons living with CHB infection and complement similar recent published guidance by WHO on the prevention care and treatment of infection due to the hepatitis C virus (HCV). In contrast to several recent international guidelines on the management of CHB infection from the United States Europe Asia-Pacific and the United Kingdom (UK) the primary audience for these WHO guidelines is country programme managers in all settings but particularly in LMICs to help plan the development and scale up of hepatitis B prevention care and treatment. These guidelines are also intended for health-care providers who care for persons with CHB in these settings. The recommendations are structured along the continuum of care for persons with CHBa from initial assessment of stage of disease and eligibility for treatment to initiation of first-line antiviral therapy and monitoring for disease progression toxicity and HCC and switch to second-line drugs in persons with treatment failure. They are intended for use across age groups and adult populations. The recommendations in these guidelines promote the use of simple non-invasive diagnostic tests to assess the stage of liver disease and eligibility for treatment; prioritize treatment for those with most advanced liver disease and at greatest risk of mortality; and recommend the preferred use of nucleos(t)ide analogues with a high barrier to drug resistance (tenofovir and entecavir and entecavir in children aged 2–11 years) for first- and second-line treatment. These guidelines also recommend lifelong treatment in those with cirrhosis; and regular monitoring for disease progression toxicity of drugs and early detection of HCC. An additional chapter highlights management considerations for specific populations including those coinfected with HIV HCV and hepatitis D virus (HDV); children and adolescents; and pregnant women.
Non Alcoholic Fatty Liver Disease
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Author : Rodrigo Valenzuela Baez
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-03-21
Non Alcoholic Fatty Liver Disease written by Rodrigo Valenzuela Baez and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.
Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment.
Boundary Features Classifying Chronic Liver Disease
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Author : Daniel V
language : en
Publisher: Self Publisher
Release Date : 2024-01-22
Boundary Features Classifying Chronic Liver Disease written by Daniel V and has been published by Self Publisher this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-22 with Health & Fitness categories.
"Boundary Features Classifying Chronic Liver Disease," written by Daniel V, is an authoritative and comprehensive book that provides a meticulous examination of the boundary features involved in classifying chronic liver disease. This insightful work encompasses a wide range of topics and offers a detailed analysis of the complex nature of liver diseases. The book begins by exploring the fundamental concepts and definitions related to chronic liver disease, including liver cirrhosis, liver fibrosis, hepatitis (including viral and autoimmune hepatitis), alcohol-related liver disease, and non-alcoholic fatty liver disease. It delves into the essential diagnostic tools, such as liver function tests, liver enzymes, liver biopsy, and liver imaging techniques, that aid in the accurate identification and classification of liver diseases. With a particular focus on chronic liver diseases, the book delves into various aspects of liver health, including liver inflammation, liver scarring, liver damage, and liver failure. It addresses critical topics such as liver cancer, hepatocellular carcinoma, and hepatic steatosis, shedding light on their classification and impact on the overall disease progression. Furthermore, the book examines the essential methods for liver disease management, liver transplantation, and the latest advancements in liver disease treatment. It explores liver disease prognosis, prevention strategies, risk factors, epidemiology, and the role of genetic and lifestyle factors in the development of liver diseases. In addition, the book provides valuable insights into liver disease research, guidelines, monitoring techniques, and the significance of liver-specific markers and biomarkers in disease diagnosis and assessment. It emphasizes the importance of public health initiatives, healthcare systems, and educational campaigns in tackling the burden of liver disease. Written in a comprehensive and accessible manner, "Boundary Features Classifying Chronic Liver Disease" is an indispensable resource for healthcare professionals, researchers, students, and anyone seeking a deeper understanding of chronic liver disease classification, diagnosis, management, and its broader implications in public health and healthcare.
Handbook Of Liver Disease
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Author : Lawrence Samuel Friedman
language : en
Publisher:
Release Date : 2004
Handbook Of Liver Disease written by Lawrence Samuel Friedman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.