The Evolving Landscape Of Liver Cirrhosis Management


The Evolving Landscape Of Liver Cirrhosis Management
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The Evolving Landscape Of Liver Cirrhosis Management


The Evolving Landscape Of Liver Cirrhosis Management
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Author : Hitoshi Yoshiji
language : en
Publisher: Springer Nature
Release Date : 2019-08-29

The Evolving Landscape Of Liver Cirrhosis Management written by Hitoshi Yoshiji and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-29 with Medical categories.


This book comprehensively covers the latest developments in the diagnosis and treatment of liver cirrhosis, including molecular mechanisms and therapeutic strategies. It elaborates on and explores the relation between chronic liver disease (CLD) and its causes, including viral hepatitis, steatohepatitis, autoimmune liver diseases and/or inherited liver diseases, and sustained liver injury. Furthermore, it discusses various complications such as hepatic encephalopathy, ascites, sarcopenia, esophagogastric varices, muscle cramps and pruritus, and the fact that it frequently leads to the development of hepatocellular carcinoma. CLD is becoming a growing issue with substantial effects on public health, and Evolving Landscape in Management of Liver Cirrhosis provides scholars in gastroenterology and hepatology with invaluable insights. At the same time, it is a valuable resource for clinicians specializing in gastroenterology and hepatology as well as for researchers who are curious about new research on liver disease.



Immunotherapy Of Hepatocellular Carcinoma


Immunotherapy Of Hepatocellular Carcinoma
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Author : Tim F. Greten
language : en
Publisher: Springer
Release Date : 2017-10-04

Immunotherapy Of Hepatocellular Carcinoma written by Tim F. Greten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-04 with Medical categories.


In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.



Changing Landscape Of Heart Failure Imaging An Issue Of Heart Failure Clinics An Issue Of Heart Failure Clinics E Book


Changing Landscape Of Heart Failure Imaging An Issue Of Heart Failure Clinics An Issue Of Heart Failure Clinics E Book
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Author : Purvi Parwani
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-09-19

Changing Landscape Of Heart Failure Imaging An Issue Of Heart Failure Clinics An Issue Of Heart Failure Clinics E Book written by Purvi Parwani and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.


In this issue of Heart Failure Clinics, guest editor Dr. Purvi Parwani brings her considerable expertise to the topic of the Changing Landscape of Heart Failure Imaging. Top experts cover the latest updates in heart failure imaging; imaging in HCM: beyond risk stratification; aortic stenosis: advanced Imaging parameters and the changing treatment landscape; mitral regurgitation: advanced Imaging parameters and the changing treatment landscape; heart failure preserved EF in women; and more. Contains 12 relevant, practice-oriented topics including artificial intelligence in heart failure imaging; ischemic cardiomyopathy: imaging-guided therapies; evaluation and management of cardiac sarcoidosis with advanced imaging; viral myocarditis and dilated cardiomyopathy: changing diagnostic insight from advanced imaging; and more. Provides in-depth clinical reviews on the changing landscape of heart failure imaging, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.



Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics E Book


Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics E Book
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Author : Nader Rifai
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-09-02

Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics E Book written by Nader Rifai and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Medical categories.


Master clinical lab testing skills with the condensed version of the Tietz Textbook! Designed for use by CLS students, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 9th Edition provides a streamlined guide to the clinical chemistry knowledge you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry educator Nader Rifai, this textbook shows how to select and perform diagnostic lab tests, and how to accurately evaluate results. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Authoritative, foundational content mirrors that in the Tietz "bible" of laboratory medicine but in a more concise way. Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. Clinical cases from the Coakley Collection demonstrate how concepts from the text are applied in real-life scenarios. More than 400 illustrations and easy-to-read summary tables help you better understand and remember key concepts. Learning objectives, key words with definitions, and review questions are included in each chapter to make learning easier. NEW! Updated content throughout the text keeps you up to date on the latest techniques, instrumentation, and technologies. NEW! Additional questions are added to each chapter for subject reinforcement. NEW! Access to Adaptive Learning courses in clinical chemistry and molecular diagnostics is provided on the Evolve website.



50 Studies Every Surgeon Should Know


50 Studies Every Surgeon Should Know
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Author : SreyRam Kuy
language : en
Publisher: Oxford University Press
Release Date : 2017-10-13

50 Studies Every Surgeon Should Know written by SreyRam Kuy and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-13 with Medical categories.


50 Studies Every Surgeon Should Know presents key studies that have shaped the practice of surgery. Selected using a rigorous methodology, the studies cover topics including: vascular, colorectal, bariatric, abdominal, hernial, and endocrine surgery, surgical outcomes, surgical oncology, trauma and surgical critical care, and studies of historical interest. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.



Variceal Bleeding In Liver Cirrhosis


Variceal Bleeding In Liver Cirrhosis
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Author : Xiaozhong Guo
language : en
Publisher: Springer Nature
Release Date : 2020-11-02

Variceal Bleeding In Liver Cirrhosis written by Xiaozhong Guo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-02 with Medical categories.


This book discusses the management of variceal bleeding in liver cirrhosis, covering a wide range of topics, including epidemiology, mechanism, diagnosis and monitoring, prophylaxis, treatment, and prognostic assessment. It also presents the latest research in the field, such as non-invasive approaches, self-expanding metal stents, hemostatic powder, and early TIPS. The book is a valuable resource for physicians wanting to establish standard treatment strategies, researchers launching innovative clinical and experimental studies, and also for patients and their relatives wishing to gain a better understanding of this disease.



Diagnostic Molecular Pathology


Diagnostic Molecular Pathology
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Author : William B. Coleman
language : en
Publisher: Academic Press
Release Date : 2016-10-05

Diagnostic Molecular Pathology written by William B. Coleman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-05 with Science categories.


Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests



Liver Cirrhosis


Liver Cirrhosis
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Author : Georgios Tsoulfas
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-07-05

Liver Cirrhosis written by Georgios Tsoulfas and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-05 with Medical categories.


Liver cirrhosis represents one of the major challenges for most physicians and surgeons on a global scale. This book provides practicing hepatologists, gastroenterologists and liver surgeons with a valuable tool in their efforts to understand the (molecular) mechanisms involved, be updated regarding the newest and less invasive diagnostic methods, and educate themselves about the challenges involved in the management of liver cirrhosis and its complications. The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of liver cirrhosis, giving us a well-rounded overview.



Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book


Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book
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Author : Elizabeth J Carey
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-13

Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book written by Elizabeth J Carey and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Medical categories.


The Guest Editors have put together an issue of clinical reviews that provides the most current look at PBC. Authors, all experts in their respective areas, have submitted articles in the following areas: Changes in epidemiology of PBC; Genetic and epigenetics in PBC; Role of bile acids and the bicarbonate umbrella in the pathogenesis of PBC; Current treatment options in PBC; Work in progress: Drugs in development; Natural history of PBC in the UDCA era: Role of scoring systems; Treatment of Pruritus: Tricks of the trade; Chronic complications of cholestasis: Work-up and Management; Individualizing care: Management beyond medical therapy; Role of liver biopsy: When to do, how to stage; AMA-negative PBC: Is it really the same as AMA-positive PBC?; New thoughts on Overlap syndrome with auto-immune hepatitis; and Current status of liver transplantation for PBC.



Hepatocellular Carcinoma Moving Into The 21st Century An Issue Of Clinics In Liver Disease E Book


Hepatocellular Carcinoma Moving Into The 21st Century An Issue Of Clinics In Liver Disease E Book
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Author : Catherine Frenette
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-10-22

Hepatocellular Carcinoma Moving Into The 21st Century An Issue Of Clinics In Liver Disease E Book written by Catherine Frenette and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-22 with Medical categories.


In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editor Dr. Catherine Frenette has assembled expert authors to provide current updates on Hepatocellular Carcinoma (HCC). This issue asks important questions and provides answers and current thoughts on the staging and treatment of HCC. Clinical review articles are specifically dedicated to the following topics: The Changing Global Epidemiology of Hepatocellular Carcinoma; Prevention Strategies for HCC; Biomarkers or Biopsy for Diagnosis of HCC; Screening and Surveillance Strategies to Improve the Chance of Success; Imaging Diagnosis of HCC; Surgical Resection: Old dog--Any new tricks; Hepatocellular Carcinoma and Liver Transplant: How Will Organ Allocation Changes Affect the HCC Patient Within Transplant Criteria; Downstaging to Liver Transplant: Success Involves Choosing the Right Patient; Locoregional Therapies for Hepatocellular Carcinoma: What has Changed in the Past Ten Years; External Beam Radiotherapy: Is There a Place for This in HCC Treatment; Tyrosine Kinase Inhibitors and Hepatocellular Carcinoma; Immuno-oncology for Hepatocellular Carcinoma: The Present and the Future; Management of Side Effects of Systemic Therapies for HCC: Guide for the Hepatologist; and Why a Multi-disciplinary Tumor Board is Critical for Success with Hepatocellular Carcinoma. Readers will come away with the information they need to improve patient outcomes in the patient with HCC.