Probing Ribonuclease A Catalysis Using Non Natural Nucleic Acids
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Probing Ribonuclease A Catalysis Using Non Natural Nucleic Acids
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Author : Bradley Roger Kelemen
language : en
Publisher:
Release Date : 1999
Probing Ribonuclease A Catalysis Using Non Natural Nucleic Acids written by Bradley Roger Kelemen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Ribonucleases Part A Functional Roles And Mechanisms Of Action
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-09-26
Ribonucleases Part A Functional Roles And Mechanisms Of Action written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-26 with Science categories.
This first of two volumes provides up-to-date, methods-related information on ribonuclease functions, assays, and applications. Chapter topics include the identification of, characterization of, and assays for secreted ribonucleases; viral ribonucleases, artificial and engineered ribonucleases, and ribozymes. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Artificial Nucleases
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Author : Marina A. Zenkova
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-07
Artificial Nucleases written by Marina A. Zenkova and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-07 with Medical categories.
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.
Structural And Catalytic Roles Of Metal Ions In Rna
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Author : Astrid Sigel
language : en
Publisher: de Gruyter
Release Date : 2015
Structural And Catalytic Roles Of Metal Ions In Rna written by Astrid Sigel and has been published by de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Metals categories.
First published by the Royal Society of Chemistry in 2009 (volumes 5 & 6), 2010 (volume 7), and 2011 (volumes 8 & 9).
Histological And Histochemical Methods Fifth Edition
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Author : John Kiernan
language : en
Publisher: Scion Publishing Ltd
Release Date : 2015-06-08
Histological And Histochemical Methods Fifth Edition written by John Kiernan and has been published by Scion Publishing Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-08 with Science categories.
This fifth edition of Histological and Histochemical Methods continues to provide a clear and consistent introduction to the techniques, description and analysis of the chemical and physical principles of fixation, tissue processing, staining, enzyme location, immunohistochemistry and other key procedures. The overall structure of the book remains unchanged, but the content has been heavily revised to update the techniques used in line with recent technological advances. Additionally, there are new sections on: Artefacts and troubleshooting Methods for microorganisms and fungi in sections Methods for various pigments and mineral deposits in tissues Methods for skeletal elements (bone, cartilage) in whole-mounts Histological and Histochemical Methods 5e is essential reading for students, lecturers, researchers and professionals using histological and histochemical techniques. From reviews: "Histological and Histochemical Methods is a tour de force wholly suited to the modern age of histology and Professor Kiernan has triumphed again. To cover so much ground clearly and concisely while including the justification of the underlying chemistry makes this book unique. There should not be a histology laboratory or an undergraduate library that does not own a copy." Biotechnic & Histochemistry 2016, 91(2): 145. "This book should be present on the bookshelves of every research or analysis laboratory where histology and histochemistry are routinely used, as an essential reference source of basic and practical information for scientists and technicians." European Journal of Histochemistry, 2016, vol. 60.
Molecular Methods For Virus Detection
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Author : Danny L. Wiedbrauk
language : en
Publisher: Elsevier
Release Date : 1995-02-08
Molecular Methods For Virus Detection written by Danny L. Wiedbrauk and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-02-08 with Science categories.
Molecular diagnostic procedures have been described in a number of recent books and articles. However, these publications have not focused on virus detection, nor have they provided practical protocols for the newer molecular methods. Written by the inventors or principal developers of these technologies, Molecular Methods for Virus Detection provides both reviews of individual methods and instructions for detecting virus nucleic acid sequences in clinical specimens. Each procedure includes quality assurance protocols that are often ignored by other methodology books. Molecular Methods for Virus Detection provides clinically relevant procedures for many of the newer diagnostic methodologies. Provides state-of-the-art PCR methods for amplification, quantitation, in situ hybridization, and multiplex reactions Goes beyond PCR with protocols for 3SR, NASBA, LCR, SDA, and LAT Covers important virus detection methods such as in situ hybridization; Southern, dot, and slot blots; branched chain signal amplification; and chemiluminescence Includes quality control information crucial in research and clinical laboratories Most chapters are written by the inventors and principal developers of the methodologies Includes color plates, 77 figures, and 18 tables
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2008
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Dissertations, Academic categories.
Bioinorganic Chemistry Of Copper
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Author : K.D. Karlin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bioinorganic Chemistry Of Copper written by K.D. Karlin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Bioinorganic Chemistry of Copper focuses on the vital role of copper ions in biology, especially as an essential metalloenzyme cofactor. The book is highly interdisciplinary in its approach--the outstanding list of contributors includes coordination chemists, biochemists, biophysicists, and molecular biologists. Chapters are grouped into major areas of research interest in inorganic copper chemistry, spectroscopy, oxygen chemistry, biochemistry, and molecular biology. The book also discusses basic research of great potential importance to pharmaceutical scientists. This book is based on the first Johns Hopkins University Copper Symposium, held in August 1992. Researchers in chemistry, biochemistry, molecular biology, and medicinal chemistry will find it to be an essential reference on its subject.
Origins Of The Earth Moon And Life
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Author : Akio Makishima
language : en
Publisher: Elsevier
Release Date : 2017-01-27
Origins Of The Earth Moon And Life written by Akio Makishima and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with Science categories.
Origins of the Earth, Moon, and Life in the Solar System: An Interdisciplinary Approach presents state-of-the-art knowledge that is based on theories, experiments, observations, calculations, and analytical data from five astro-sciences, astronomy, astrobiology, astrogeology, astrophysics, and cosmochemistry. Beginning with the origin of elements, and moving on to cover the formation of the early Solar System, the giant impact model of the Earth and Moon, the oldest records of life, and the possibility of life on other planets in the Solar System, this interdisciplinary reference provides a complex understanding of the planets and the formation of life. Synthesizing concepts from all branches of astro-sciences into one, the book is a valuable reference for researchers in astrogeology, astrophysics, cosmochemistry, astrobiology, astronomy, and other space science fields, helping users better understand the intersection of these sciences. Includes extensive figures and tables to enhance key concepts Uses callout boxes throughout to provide context and deeper explanations Presents up-to-date information on the universe, stars, planets, moons, and life in the solar system Combines knowledge from the fields of astrogeology, astrophysics, cosmochemistry, astrobiology, and astronomy, helping readers understand the origins of the Earth, the moon, and life in our solar system