Problem Solving In Enzyme Biocatalysis
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Problem Solving In Enzyme Biocatalysis
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Author : Andrés Illanes
language : en
Publisher: John Wiley & Sons
Release Date : 2013-10-02
Problem Solving In Enzyme Biocatalysis written by Andrés Illanes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-02 with Technology & Engineering categories.
Enzyme biocatalysis is a fast-growing area in process biotechnology that has expanded from the traditional fields of foods, detergents, and leather applications to more sophisticated uses in the pharmaceutical and fine-chemicals sectors and environmental management. Conventional applications of industrial enzymes are expected to grow, with major opportunities in the detergent and animal feed sectors, and new uses in biofuel production and human and animal therapy. In order to design more efficient enzyme reactors and evaluate performance properly, sound mathematical expressions must be developed which consider enzyme kinetics, material balances, and eventual mass transfer limitations. With a focus on problem solving, each chapter provides abridged coverage of the subject, followed by a number of solved problems illustrating resolution procedures and the main concepts underlying them, plus supplementary questions and answers. Based on more than 50 years of teaching experience, Problem Solving in Enzyme Biocatalysis is a unique reference for students of chemical and biochemical engineering, as well as biochemists and chemists dealing with bioprocesses. Contains: Enzyme properties and applications; enzyme kinetics; enzyme reactor design and operation 146 worked problems and solutions in enzyme biocatalysis.
Immobilized Biocatalysts
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Author : Peter Grunwald
language : en
Publisher: MDPI
Release Date : 2018-11-14
Immobilized Biocatalysts written by Peter Grunwald and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-14 with Science categories.
This book is a printed edition of the Special Issue "Immobilized Biocatalysts" that was published in Catalysts
Enzyme Cascade Design And Modelling
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Author : Selin Kara
language : en
Publisher: Springer Nature
Release Date : 2021-02-24
Enzyme Cascade Design And Modelling written by Selin Kara and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-24 with Science categories.
This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.
Industrial Enzyme Applications
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Author : Andreas Vogel
language : en
Publisher: John Wiley & Sons
Release Date : 2019-07-10
Industrial Enzyme Applications written by Andreas Vogel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Science categories.
This reference is a "must-read": It explains how an effective and economically viable enzymatic process in industry is developed and presents numerous successful examples which underline the efficiency of biocatalysis.
Biocatalyst Immobilization
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Author : Maria Lujan Ferreira
language : en
Publisher: Academic Press
Release Date : 2022-11-12
Biocatalyst Immobilization written by Maria Lujan Ferreira and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-12 with Science categories.
Biocatalyst Immobilization: Foundations and Applications provides a comprehensive overview of biocatalytic immobilization processes, as well as methods for study, characterization and application. Early chapters discuss current progress in enzyme immobilization and methods for selecting and pretreating enzymes prior to immobilization, with an emphasis on navigating common challenges and employing enzyme supports and post immobilization treatments to impact enzymatic activity. Process-based chapters instruct on measuring and reporting on enzyme immobilization efficiency, protein final content, quantification of reaction products, and the use of nanomaterials to characterize immobilized enzymes. Later chapters examine recent advances, including novel enzymatic reactors, multi-enzymatic biocatalysts, enzymatic biosensors, whole cell immobilization, the industrial application of immobilized enzymes, and perspectives on future trends. - Provides a thorough overview of biocatalyst and enzyme immobilization for research and practical application - Presents methods based content that instructs in enzyme immobilization pretreatment, enzyme supports, post immobilization treatments, measuring enzyme immobilization efficiency, quantification of reaction products, and whole cell immobilization - Features chapter contributions from international leaders in the field
Nanomaterials For Biocatalysis
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Author : Guillermo R. Castro
language : en
Publisher: Elsevier
Release Date : 2021-10-12
Nanomaterials For Biocatalysis written by Guillermo R. Castro and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-12 with Technology & Engineering categories.
Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications. - Explains the major fabrication techniques and applications of nanobiocatalysts - Shows how nanobiocatalysts are used in a variety of environmental and biomedical sectors - Assesses the major challenges associated with the widespread manufacture of nanobiocatalysts
Removal Of Emerging Contaminants Through Microbial Processes
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Author : Maulin P Shah
language : en
Publisher: Springer Nature
Release Date : 2020-10-14
Removal Of Emerging Contaminants Through Microbial Processes written by Maulin P Shah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-14 with Science categories.
The abundance of organic pollutants found in wastewater affect urban surface waters. Traditional wastewater management technologies focus on the removal of suspended solids, nutrients and bacteria, however, new pollutants such as synthetic or naturally occurring chemicals are often not monitored in the environment despite having the potential to enter the environment and cause adverse ecological and human health effects. Collectively referred to as "emerging contaminants," they are mostly derived from domestic activities and occur in trace concentrations ranging from pico to micrograms per liter. Environmental contaminants are resistant to conventional wastewater treatment processes and most of them remain unaffected, causing contamination of receiving water. This in turn leads to the need for advanced wastewater treatment processes capable of removing environmental contaminants to ensure safe fresh water sources. This book provides an up-to-date overview of the current bioremediation strategies, including their limitations, challenges and their potential application to remove environmental pollutants. It also introduces the latest trends and advances in environmental bioremediation, and presents the state-of-the-art in biological and chemical wastewater treatment processes. As such, it will appeal to researchers and policy-makers, as well as undergraduate and graduate environmental sciences students.
Enzyme Biocatalysis
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Author : Andrés Illanes
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-19
Enzyme Biocatalysis written by Andrés Illanes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-19 with Technology & Engineering categories.
This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds. We sincerely hope that this book will represent an element in the toolbox of gr- uate students in applied biology and chemical and biochemical engineering and also of undergraduate students with formal training in organic chemistry, biochemistry, thermodynamics and chemical reaction kinetics. Beyond that, the book pretends also to illustrate the potential of biocatalytic processes with case studies in the ?eld of organic synthesis, which we hope will be of interest for the academia and prof- sionals involved in R&D&I. If some of our young readers are encouraged to engage or persevere in their work in biocatalysis this will certainly be our more precious reward.
Biocatalysis In Asymmetric Synthesis
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Author : Gonzalo De Gonzalo
language : en
Publisher: Elsevier
Release Date : 2024-05-04
Biocatalysis In Asymmetric Synthesis written by Gonzalo De Gonzalo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-04 with Science categories.
Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion of synthesizing biological catalysts using asymmetric synthesis, for applications across research and industry. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries, with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products. - Explores biocatalysts as exquisite catalysts for fine chiral compound synthesis in different reaction media - Features both foundational overviews and applied, practical examples across research and industry - Includes chapter contributions from international leaders in the field
Pharmaceutical Biocatalysis
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Author : Peter Grunwald
language : en
Publisher: CRC Press
Release Date : 2019-11-07
Pharmaceutical Biocatalysis written by Peter Grunwald and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-07 with Business & Economics categories.
This volume provides an insight into the future strategies for commercial biocatalysis with a focus on sustainable technologies, together with chemoenzymatic and biotechnological approaches to synthesize various types of approved and new active pharmaceutical ingredients (APIs) via proven and latest synthetic routes using single-step biocatalytic or enzyme cascade reactions. Many of these drugs act as enzyme inhibitors, as discussed in a chapter with a variety of examples. The targeted enzymes are involved in diseases such as different cancers, metastatic and infectious diseases, osteoporosis, and cardiovascular disorders. The biocatalysts employed for API synthesis include hydrolytic enzymes, alcohol dehydrogenases, laccases, imine reductases, reductive aminases, peroxygenases, cytochrome P450 enzymes, polyketide synthases, transaminases, and halogenases. Many of them have been improved with respect to their properties by engineering methods. The book discusses the syntheses of drugs, including alkaloids and antibiotics, non-ribosomal peptides, antimalarial and antidiabetic drugs, prenylated xanthones, antioxidants, and many important (chiral) intermediates required for the synthesis of pharmaceuticals.