Progress Of Allo And Xeno Transplantation Facilitating The Initial Xeno Kidney And Islet Clinical Trials
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Progress Of Allo And Xeno Transplantation Facilitating The Initial Xeno Kidney And Islet Clinical Trials
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Author : Burcin Ekser
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-11
Progress Of Allo And Xeno Transplantation Facilitating The Initial Xeno Kidney And Islet Clinical Trials written by Burcin Ekser and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-11 with Medical categories.
Community Series In Progress Of Allo And Xeno Transplantation Facilitating The Initial Xeno Kidney And Islet Clinical Trials Volume Ii
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Author : Lisha Mou
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-21
Community Series In Progress Of Allo And Xeno Transplantation Facilitating The Initial Xeno Kidney And Islet Clinical Trials Volume Ii written by Lisha Mou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-21 with Medical categories.
Owing to the availability of more advanced genetically engineered pigs, more immunological and physiological barriers have been overcome. With the results of pig organ xenotransplantation steadily improving, consideration is now given to the first clinical trials of xenotransplantation. The first step is kidneys, but possibilities also exist in pig islet transplantation for patients with diabetes.
The Future Direction Toward Immunological Issues Of Allo And Xeno Islet Transplantation
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Author : Chunming Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-19
The Future Direction Toward Immunological Issues Of Allo And Xeno Islet Transplantation written by Chunming Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-19 with Medical categories.
Islet transplantation can effectively control the blood glucose of fragile type 1 diabetes patients, thus significantly reducing hyperglycemia and improving HbA1c, and has become one of the ideal options for the treatment of type 1 diabetes patients. However, despite great progress, current islet transplantation is still limited by the isolation process, the culture period, and the rapid decline in islet functional activity after transplantation. Long-term survival and function of islet grafts are affected by non-immune and immune-related factors. To overcome these obstacles, various strategies, including stem cell combination transplantation, have been used for islet transplantation. Stem cells can promote vascular regeneration of islets and reduce inflammation and innate immune damage in the early stage of islet transplantation through potential immunomodulatory and anti-inflammatory effects. Therefore, combined transplantation of islets and stem cells can improve the survival rate of islets. In view of this, we are very honored and pleased to have some of the leading research groups in diabetes research contribute to the topic of islet transplantation. This special issue of the current landscape is dedicated to summarizing the latest advancements in allogenic and xenogenic islet transplantation and strategies to overcome its current limitations. Diversified topics related to islet isolation, islet transplantation, stem cells, immune regulation, angiogenesis, and strategies overcoming immune responses are welcome.
Transplantation Of The Pancreas
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Author : Rainer W.G. Gruessner
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-04-27
Transplantation Of The Pancreas written by Rainer W.G. Gruessner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-27 with Medical categories.
Although pancreas transplants have been performed for more than 30 years, the last few years have witnessed significant growth in the options available for pancreas transplantation. Transplantation of the Pancreas, edited by Drs. Gruessner and Sutherland provides a state-of-the-art, definitive reference work on pancreas transplantation for transplant surgeons and physicians as well as for endocrinologists, diabetologists, nephrologists, and neurologists. The editors, from the renowned University of Minnesota Transplant Division and the Diabetes Institute, have assembled a group of renowned experts to provide an all-inclusive overview of pancreas transplantation. The text features insights on the pathophysiology of diabetes mellitus and the limitations of nontransplant treatments, highlights experimental research and clinical history of pancreas transplantation, and compares and contrasts different surgical procedures. The discussions detail the broad spectrum of post-transplant complications and their treatments, which frequently require skills in general, vascular, and laparoscopic surgery; interventional radiology; critical care; and infectious disease. Chapters on pretransplant evaluation, immunosuppression, immunology, pathology, long-term outcome, quality of life, and cost-effectiveness focus on issues unique to pancreas recipients. Evolving areas, such as pretransplant evaluation of pancreas transplant candidates, living donation, and the current status of islet transplantation are discussed. Augmented by more than 280 illustrations, including full color line drawings created exclusively for the text, this book is the standard reference for all transplant professionals as well as for all physicians caring for the transplant patient.
Kidney Transplantation E Book
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Author : Stuart J. Knechtle
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-11-27
Kidney Transplantation E Book written by Stuart J. Knechtle and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-27 with Medical categories.
A must-have resource for all members of the transplant team, Kidney Transplantation: Principles and Practice, 9th Edition, provides comprehensive, up-to-date information on every aspect of this complex field. Drs. Stuart J. Knechtle and Lorna P. Marson, along with a global team of internationally renowned surgeons and nephrologists, offer balanced coverage of both surgical techniques and medical considerations related to kidney transplantation. With updates from cover to cover, this core reference delivers the practical guidance you need to achieve optimal outcomes in both adults and children. - Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression. - Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field. - Includes new chapters on xenotransplantation and COVID-19 in renal transplantation. - Adds new information on normothermic regional perfusion to the discussion of DCD organ donation and ethics of transplantation, and new information on iBox (the first universal algorithm for predicting the risk of kidney transplant loss) to the biomarkers section. - Provides relevant, up-to-date information on kidney transplant for all members of the transplant team, with practical information on applied science, clinical information, and surgical procedures. - Features intraoperative videos and hundreds of superb illustrations to help readers visualize key concepts and nuances of renal transplantation. - Covers each major immunosuppressive drug in individual chapters, and provides a reference list of all randomized trials for convenient access to critical information.
Kidney Transplantation Principles And Practice E Book
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Author : Stuart J. Knechtle
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-08-31
Kidney Transplantation Principles And Practice E Book written by Stuart J. Knechtle and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-31 with Medical categories.
Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, in both adults and children. - Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression. - Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field. - Includes new information on desensitization and considerable new data on the clinical use of costimulation blockade. - Keeps you current with new chapters on kidney allocation policy that reflects the ethical and societal values of different countries and populations; and biomarkers of kidney injury and rejection, including the need for better monitoring tools to guide therapy and patient management. - Covers hot topics such as management of chronic allograft failure, the sensitized patient and antibody-mediated rejection, and paired exchange principles. - Features hundreds of superb illustrations to help you visualize key concepts and nuances of renal transplantation. - Provides dynamic visual guidance with new real-time video coverage of ultrasound-guided pancreas allograft biopsy; a new animation of calcineurin inhibitor mechanism of action animation; and videos that demonstrate the formation of an immune synapse, 3-D rotational images of immune synapses, an NK cell killing its target, peritoneal dialysis-catheter insertion techniques, laparoendoscopic single site (LESS) donor nephrectomy, and more. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1993
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Xenotransplantation
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1996-07-12
Xenotransplantation written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-12 with Medical categories.
Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Cell Transplantation
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Author :
language : en
Publisher:
Release Date : 1996
Cell Transplantation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Cell transplantation categories.
Transplantation Bioengineering And Regeneration Of The Endocrine Pancreas
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Author : Giuseppe Orlando
language : en
Publisher: Academic Press
Release Date : 2019-11-09
Transplantation Bioengineering And Regeneration Of The Endocrine Pancreas written by Giuseppe Orlando and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-09 with Science categories.
Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. - Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation - Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more - Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes