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Prostaglandin E1 In Vascular Disease


Prostaglandin E1 In Vascular Disease
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Prostaglandin E1 In Vascular Disease


Prostaglandin E1 In Vascular Disease
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Author : Antonio Strano
language : en
Publisher:
Release Date : 1989

Prostaglandin E1 In Vascular Disease written by Antonio Strano and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Arteriosclerosis categories.




Prostaglandin E1 In Atherosclerosis


Prostaglandin E1 In Atherosclerosis
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Author : Helmut Sinzinger
language : en
Publisher:
Release Date : 1986

Prostaglandin E1 In Atherosclerosis written by Helmut Sinzinger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Atherosclerosis categories.




Prostaglandin E1


Prostaglandin E1
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Author : Curt Diehm
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Prostaglandin E1 written by Curt Diehm and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Although prostaglandin El (PGE ) has been clinically available for a long 1 time, only in recent years has its effectiveness in peripheral arterial occlusive disease been confirmed in controlled studies. Not surprisingly, the favour able results achieved both in patients with critical limb ischaemia and in those with intermittent claudication has stimulated research activities into the clinical pharmacology of this prostaglandin. As a consequence of these efforts, exciting new findings have revealed that PGE has anti thrombotic , endothelium-stabilizing and leucocyte-stabi 1 lizing properties as well as effects on lipid metabolism, all of which, quite apart from its well-known anti-aggregating and vasodilator effects, may add to the clinical efficacy of the substance. New data have also been gathered on the metabolism of PGE most b notably the detection of 13,14-dihydro-PGE a metabolite which was b recently isolated in humans following the administration of PGE . Being 1 biologically active, the pharmacodynamic spectrum of 13,14-dihydro-PGE 1 very closely resembles that of PGE . This finding may help to explain the 1 efficacy of PGE despite its rapid metabolization when given intravenously.



Prostaglandin E1 In Atherosclerosis


Prostaglandin E1 In Atherosclerosis
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Author : Helmut Sinzinger
language : en
Publisher:
Release Date : 1986-11-01

Prostaglandin E1 In Atherosclerosis written by Helmut Sinzinger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-11-01 with categories.




Prostaglandin E1 In Atherosclerosis


Prostaglandin E1 In Atherosclerosis
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Author : Helmut Sinzinger
language : en
Publisher:
Release Date : 1986

Prostaglandin E1 In Atherosclerosis written by Helmut Sinzinger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Arteriosclerosis categories.




Prostaglandin E1


Prostaglandin E1
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Author : C. Diehm
language : en
Publisher: Springer Verlag
Release Date : 1991-01-01

Prostaglandin E1 written by C. Diehm and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-01 with Medical categories.




Critical Limb Ischemia


Critical Limb Ischemia
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Author : Svante Horsch
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Critical Limb Ischemia written by Svante Horsch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Chronic critical limb ischemia remains one of the most frequent causes of illness and hospitalization in the western world. Interest in critical limb ischemia has increased markedly in recent years. There have been significant achievements in diagnostic pro cedures as well as in the medical, invasive, and surgical treatment of patients with critical limb ischemia. Despite a considerable research effort, the pathophysiological mechanisms of critical limb ischemia in humans remains to be established. Prominent is the increasing interest in the microcirculation, as well as in the hemorheological, hemostatic and inflammatory changes which may promote critical limb ischemia. Further research is necessary to quantify the relevance of microcirculatory in vestigations in terms of predicting the prognosis or to evaluate the effects of new therapies. Our main task is to offer the patient the best possible therapy in order to avoid limb loss and to improve quality of life. The various methods of treatment, their suc cess rates, and their complications, must be carefully evaluated and discussed. This volume presents the complex field of diagnosis and treatment of critical limb ischemia. The diagnosis and treatment involves different specialists including angio logists, interventional radiologists, vascular surgeons, plastic surgeons, diabeto logists, etc. Individual chapters have been written by Belgian and German experts in the various specialities, who present their own experience. We are very grateful that these experts have joined us to produce this book on the epidemiology, pathophysiology, and rational therapy.



Prostaglandins Platelets Lipids


Prostaglandins Platelets Lipids
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Author : Hadley L. Conn
language : en
Publisher: Elsevier
Release Date : 2014-05-23

Prostaglandins Platelets Lipids written by Hadley L. Conn and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-23 with Medical categories.


Prostaglandins, Platelets, Lipids: New Developments in Atherosclerosis focuses on developments pertaining to atherosclerosis and suggested novel approaches for its prevention, treatment, and complications. The selection first underscores the biological importance and therapeutic potential of prostacyclin and rationale for the suppression of platelet aggregation and thrombosis by dietary manipulation of fatty acids. Discussions focus on eicosapentaenoic acid as a potential antithrombotic substance, vascular effects of prostacyclin, antithrombotic and hemostatic effects of prostacyclin, fatty acids, prostacyclin, and thrombosis, and therapeutic uses of prostacyclin. The text then examines prostaglandins and hypertension, role of platelets in stroke and transient ischemic attack, and antiplatelet agents in the prevention of acute coronary events. Topics include thrombosis and clinical complications of atherosclerosis, mechanisms in thrombosis, vascular prostaglandins and antihypertensive mechanisms, and renal prostaglandins and antihypertensive mechanisms. The book ponders on a specific inhibitor of thrombin and cardiovascular actions of prostacyclin in man, including prostacyclin and angina pectoris, prostacyclin therapy for peripheral arterial disease, and hemodynamic changes induced by prostacyclin. The selection is a dependable source of data for researchers interested in atherosclerosis.



Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension


Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension
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Author : Toshio Nakanishi
language : en
Publisher: Springer Nature
Release Date : 2020-02-28

Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension written by Toshio Nakanishi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-28 with Medical categories.


This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.



Angiogenesis In Health Disease And Malignancy


Angiogenesis In Health Disease And Malignancy
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Author : Ali Salajegheh
language : en
Publisher: Springer
Release Date : 2016-03-10

Angiogenesis In Health Disease And Malignancy written by Ali Salajegheh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-10 with Medical categories.


This book is about “Angiogenesis”. A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients. The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer. New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.