Protein Phosphorylation In Parasites
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Protein Phosphorylation In Parasites
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Author : Christian Doerig
language : en
Publisher: John Wiley & Sons
Release Date : 2013-10-11
Protein Phosphorylation In Parasites written by Christian Doerig and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-11 with Medical categories.
This is the first book to collect and summarize in one publication the efforts to use kinases or phosphatases for drug development against parasite infections. The editors and contributors comprise the Who is Who in the field, and they are comprehensive in covering every aspect of the topic, from basic research findings to translational approaches in drug development The result will be welcomed by everyone in academia and industry participating in the global effort to finally combat the major diseases caused by eukaryotic parasites. This is volume one of a two-volume treatise, the second being exclusively dedicated to efforts to combat malaria using the same approach.
Proteins And Proteomics Of Leishmania And Trypanosoma
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Author : André L.S. Santos
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-22
Proteins And Proteomics Of Leishmania And Trypanosoma written by André L.S. Santos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-22 with Medical categories.
This book contains a collection of critical reviews on the expression of biologically functional proteins in Leishmania and Trypanosoma, which was written by renowned researchers on this field. Species belonging to these trypanosomatids’ genera are etiological agents of leishmaniasis, Chagas’ disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quiet unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by Leishmania and Trypanosoma by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategies against trypanosomiasis. With these proposals in mind, the book “Proteins and Proteomics of Leishmania and Trypanosoma” encompasses (i) an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera; (ii) an updated review on the expression of biologically relevant proteins by human pathogenic trypanosomatids and their possible role in the interaction with host cells/molecules as well as a target for development of both alternative chemotherapies and vaccine; and (iii) several pictures, diagrams and tables that can be used to illustrate both undergraduate and postgraduate teaching as well as scientific lectures, being a useful resource for students and researchers.
Protein Traffic In Parasites And Mammalian Cells
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Author : J. D. Lonsdale-Eccles
language : en
Publisher:
Release Date : 1989
Protein Traffic In Parasites And Mammalian Cells written by J. D. Lonsdale-Eccles and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Carrier proteins categories.
Subversion Of Immune Cell Signalling By Parasites Volume 41 Symposia Of The British Society For Parasitology
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Author : William Harnett
language : en
Publisher: Cambridge University Press
Release Date : 2006-01-30
Subversion Of Immune Cell Signalling By Parasites Volume 41 Symposia Of The British Society For Parasitology written by William Harnett and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-30 with Science categories.
An introduction to the topic from experts in the field.
Molecular Mechanisms Of Parasite Invasion
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Author : Barbara A. Burleigh
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-05
Molecular Mechanisms Of Parasite Invasion written by Barbara A. Burleigh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-05 with Medical categories.
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Malaria Targeting Toolkit Host Parasite Interaction
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Author : Jing-wen Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10
Malaria Targeting Toolkit Host Parasite Interaction written by Jing-wen Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Science categories.
Biochemical Adaptation In Parasites
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Author : C. Bryant
language : en
Publisher: Springer
Release Date : 1989-09-30
Biochemical Adaptation In Parasites written by C. Bryant and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-09-30 with Science categories.
Encyclopedia Of Malaria
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Author :
language : en
Publisher: Springer
Release Date : 2018-07-12
Encyclopedia Of Malaria written by and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with Medical categories.
The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.
Apicomplexan Parasites
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Author : Katja Becker
language : en
Publisher: John Wiley & Sons
Release Date : 2011-01-19
Apicomplexan Parasites written by Katja Becker and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-19 with Medical categories.
This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.
Biology Of Trypanosoma Cruzi
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Author : Wanderley De Souza
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18
Biology Of Trypanosoma Cruzi written by Wanderley De Souza and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Medical categories.
Trypanosoma cruzi, an important zoonotic protozoan that causes Chagas disease, affects at least 8 million people in Latin America. Chagas disease is an important life-long infection in humans that can be divided into distinct clinical stages: the acute phase, where patient symptoms can vary from asymptomatic to severe; the indeterminate form, which is usually asymptomatic; and the chronic phase, where cardiomyopathy and/or digestive megasyndromes appear. In addition to its medical importance, T. cruzi is an interesting biological model for studying processes such as: (1) cell differentiation, where a non-infective stage transforms into an infective one; (2) cell invasion, where the infective stages are able to penetrate into a mammalian host cell, where they multiply several times and thus amplify the infection; and (3) evasion from the immune system, using several mechanisms. This book, with 13 chapters, has been organized in four major sections: 1. "Basic Biology," 2. "Biochemistry and Molecular Biology," 3. "Parasite"Host Cell Interaction," and 4 "Chemotherapy." The chapters include basic biological information on the protozoan lifecycle, including new information on parasite genomics and proteomics. In addition, they analyze the interaction with host cells as well the immune response and evasion, ending with information on experimental chemotherapy against Chagas disease.