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Protein Traffic In Parasites And Mammalian Cells


Protein Traffic In Parasites And Mammalian Cells
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Protein Traffic In Parasites And Mammalian Cells


Protein Traffic In Parasites And Mammalian Cells
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Author : J. D. Lonsdale-Eccles
language : en
Publisher:
Release Date : 1989

Protein Traffic In Parasites And Mammalian Cells written by J. D. Lonsdale-Eccles and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Carrier proteins categories.




Heat Shock Proteins Of Malaria


Heat Shock Proteins Of Malaria
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Author : Addmore Shonhai
language : en
Publisher: Springer Nature
Release Date : 2021-09-26

Heat Shock Proteins Of Malaria written by Addmore Shonhai and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-26 with Medical categories.


This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular parasite stages. Thoroughly revised, this work provides a general introduction to the structural and functional features of heat shock proteins with a special focus on their role as molecular chaperones in ensuring protein quality control. The emphasis is on the heat shock protein families from Plasmodium falciparum, and their role in proteostasis and the development of malaria pathology. Moreover, the authors explore the latest prospects of targeting heat shock proteins in antimalarial drug discovery either directly or in combination therapies. Readers will experience a functional analysis of the individual families of heat shock proteins and their cooperation in functional networks, including both the parasite-resident proteome and the exportome released into host cells during intracellular stages. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts associated with Plasmodium species are discussed in detail. The book highlights the role of heat shock proteins in the development and function of these structures. Biochemical expertise and the inclusion of novel therapeutic solutions make this collection a unique reference for experts in heat shock protein research, parasitology and infectious diseases, cell stress, molecular biology and drug discovery. Not least, advances in malaria control will contribute to ending epidemics and ensuring healthy lives in line with the UN Sustainable Development Goals.



Molecular Mechanisms Of Membrane Traffic


Molecular Mechanisms Of Membrane Traffic
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Author : D. James Morre
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Molecular Mechanisms Of Membrane Traffic written by D. James Morre and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


The study of membrane traffic in reconstituted cell-free systems has generated an unprecedented amount of new information on the biochemistry, molecular biology and genetics of membrane-based molecular events that underly normal and abnormal cellular function. Many of the individual steps have now been isolated and dissected in simple systems that permit detailed molecular analyses of transport mechanisms and their regulation. Reconstituted events of intercompartment transport include inter-membrane recognition, and controlled membrane fusion-fission reactions. Among the many advances is the growi ng awareness of a remarkabl e evolutionary conservation of many of the components involved in the many steps of membrane traffic, this realization has accelerated greatly the pace of progress in the field. This book provides a collection of participant contributions from the 1992 Summer Research Conference, "Mol ecul ar Mechani sms of Membrane Traffi c, " jointly sponsored with NATO by the American Society of Cell Biology. The conference was held May 9-13, at the Airlie Conference Center in the Virginia countryside, near Warrenton. The conference was attended by 158 scientists. A unique feature was the high proportion of young scientists among the participants. Approximately 65% were students, postdoctoral fe 11 ows and young investigators. Each attendee contri buted to the conference with either a pl atform or poster presentation.



Encyclopedia Of Malaria


Encyclopedia Of Malaria
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Author :
language : en
Publisher: Springer
Release Date : 2018-07-12

Encyclopedia Of Malaria written by and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with Medical categories.


The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.



Cell Compartments And Intracellular Trafficking Of Lipids And Proteins Impact On Biomedicine


Cell Compartments And Intracellular Trafficking Of Lipids And Proteins Impact On Biomedicine
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Author : Silvana Zanlungo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-30

Cell Compartments And Intracellular Trafficking Of Lipids And Proteins Impact On Biomedicine written by Silvana Zanlungo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-30 with Science categories.




Molecular Mechanisms Of Parasite Invasion


Molecular Mechanisms Of Parasite Invasion
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Author : Barbara A. Burleigh
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-05

Molecular Mechanisms Of Parasite Invasion written by Barbara A. Burleigh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-05 with Medical categories.


All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.



Ilrad Annual Scientific Report 1990


Ilrad Annual Scientific Report 1990
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Author : International Laboratory for Research on Animal Diseases
language : en
Publisher: ILRI (aka ILCA and ILRAD)
Release Date :

Ilrad Annual Scientific Report 1990 written by International Laboratory for Research on Animal Diseases and has been published by ILRI (aka ILCA and ILRAD) this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Ilrad Annual Report 1989


Ilrad Annual Report 1989
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Author : International Laboratory for Research on Animal Diseases
language : en
Publisher: ILRI (aka ILCA and ILRAD)
Release Date :

Ilrad Annual Report 1989 written by International Laboratory for Research on Animal Diseases and has been published by ILRI (aka ILCA and ILRAD) this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Signaling Networks And Cell Cycle Control


Signaling Networks And Cell Cycle Control
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Author : J. Silvio Gutkind
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-04-14

Signaling Networks And Cell Cycle Control written by J. Silvio Gutkind and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-14 with Medical categories.


Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Cutting-edge and highly suggestive, Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases presents a wealth of information on the emerging principles of the field, as well as an invaluable guide for all experimental and clinical investigators of cell regulation and its rapidly emerging pharmacological opportunities today.



Metal Transporters


Metal Transporters
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Author : Jose M. Arguello
language : en
Publisher: Academic Press
Release Date : 2012-10-25

Metal Transporters written by Jose M. Arguello and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-25 with Science categories.


This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise