Protein Synthesis By A Ribosomal System Derived From Yeast

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Protein Synthesis By A Ribosomal System Derived From Yeast

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Author : Shih Eh Wang
language : en
Publisher:
Release Date : 1967

Protein Synthesis By A Ribosomal System Derived From Yeast written by Shih Eh Wang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1967 with Proteins categories.

Protein Synthesis And Targeting In Yeast

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Author : Alistair J.P. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Protein Synthesis And Targeting In Yeast written by Alistair J.P. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.

Due to fundamental similarities between the yeast Saccharomyces cerevisiae and multicellular organisms at the molecular level, and the powerful range of experimental tools available for this yeast, S. cerevisiae is proving an ideal model system for studies on protein synthesis and targeting. The topics covered are: - Messenger RNA stability and translation.- The translation apparatus. - Translational control andfidelity. - Protein targeting to the mitochondrion. - Nuclear transport. - The secretory pathway. - Protein folding and degradation. - Protein splicing. Modern and often novel molecular, genetic and biochemical approaches as well as most recent data are provided. The reader will gain a comprehensive view of the current status of the field.

Observations On Protein Synthesis Using A Ribosomal System Derived From Rat Liver

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Author : Roger Lewis Heintz
language : en
Publisher:
Release Date : 1964

Observations On Protein Synthesis Using A Ribosomal System Derived From Rat Liver written by Roger Lewis Heintz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Proteins categories.

Protein Synthesis And Ribosome Structure

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Author : Knud H. Nierhaus
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-10

Protein Synthesis And Ribosome Structure written by Knud H. Nierhaus and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-10 with Science categories.

Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.

Regulation Of Ribosomal Protein Synthesis In Yeast

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Author : Charles Gorenstein
language : en
Publisher:
Release Date : 1977

Regulation Of Ribosomal Protein Synthesis In Yeast written by Charles Gorenstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.

Method For Yeast Protein Synthesis In A Cell Free System

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Author : C.H. Sissons
language : en
Publisher:
Release Date : 1978

Method For Yeast Protein Synthesis In A Cell Free System written by C.H. Sissons and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.

Studies On Initiation Of Protein Synthesis In Yeast

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Author : Welda Lajean Chaffin
language : en
Publisher:
Release Date : 1969

Studies On Initiation Of Protein Synthesis In Yeast written by Welda Lajean Chaffin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Proteins categories.

Use Of Protein Synthesis Inhibitors To Study The Biochemistry And Genetics Of The Yeast Ribosome

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Author : Daniel Gordon Schindler
language : en
Publisher:
Release Date : 1976

Use Of Protein Synthesis Inhibitors To Study The Biochemistry And Genetics Of The Yeast Ribosome written by Daniel Gordon Schindler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Saccharomyces cerevisiae categories.

Role Of Ribosomal Protein Us9 Ys16 In Translation Initiation And Elongation In Yeast Saccharomyces Cerevisiae

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Author : Supriya Jindal
language : en
Publisher:
Release Date : 2019

Role Of Ribosomal Protein Us9 Ys16 In Translation Initiation And Elongation In Yeast Saccharomyces Cerevisiae written by Supriya Jindal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.

The process of translation in all living cells is performed by ribosomes and is divided intofour major steps (initiation, elongation, termination and ribosome recycling). Ribosomesconsist of ribosomal RNA (rRNA) and proteins and are composed of two subunits smalland large. There are three major sites for tRNA binding within ribosome: the (aminoacyl)A-site which accepts the aminoacyl (aa)-tRNA; the P-site, where the peptidyl-tRNA isformed and the (exit) E-site, where deacylated tRNA exits the ribosome. These sites areformed by both rRNA and ribosomal proteins. Though rRNA are involved in the catalysisof protein synthesis, the contribution of individual ribosomal proteins to protein synthesisis not fully understood in molecular terms. Yeast ribosomal protein uS9/yRps16, isuniversally conserved and is located on the solvent side of the small ribosomal subunit. Ithas a long protruding C-terminal tail (CTT) which extends towards the mRNA cleft. ThisCTT contributes to the formation of the ribosomal P-site. uS9/yRps16 last positivelycharged C terminal residue (Arg), is invariably conserved and is believed to enhanceinteraction of the negatively charged initiator tRNA, when base-paired to AUG codon inthe P site. However, biochemical evidence in support of this notion is limited. Ourbiochemical analysis of the uS9 mutants showed that the C terminus of uS9 plays animportant role during translation initiation. We found that uS9 C-terminal residues (theirexact location and nature) are critical for efficient recruitment of the eIF2•GTP•MettRNAiMet ternary complex and for responding properly to an AUG codon in the P-site,during scanning phase of initiation. These residues also regulate hydrolysis of GTP (from eIF2•GTP•MettRNAiMet complex) to GDP and Pi. Furthermore, deletion of the last tworesidues of uS9 CTT, exhibits resistance to anisomycin, decreased association ofelongation factor eEF1A to polyribosomes at the A-site and decreased programmedribosomal frameshift (PRF) efficiency, thus showing that uS9 C terminal region modulateselongation fidelity. Therefore, we propose that uS9 CTT is critical for proper control of thecomplex interplay of events surrounding the accommodation of initiator and elongator tRNAsin the P- and A-sites of the ribosome.

Molecular Biology Of The Cell

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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.