Proteins In Solution And At Interfaces
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Proteins In Solution And At Interfaces
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Author : Juan M. Ruso
language : en
Publisher: John Wiley & Sons
Release Date : 2013-01-31
Proteins In Solution And At Interfaces written by Juan M. Ruso and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Science categories.
Explores new applications emerging from our latest understanding of proteins in solution and at interfaces Proteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology. Proteins in Solution and at Interfaces is divided into two parts: Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methods Part Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamics The book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments. Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.
Proteins At Liquid Interfaces
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Author : D. Möbius
language : en
Publisher: Elsevier
Release Date : 1998-04-24
Proteins At Liquid Interfaces written by D. Möbius and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-04-24 with Science categories.
The interfacial behaviour of surfactants and proteins, and their mixtures, is of importance in a wide range of areas such as food technology, detergency, cosmetics, coating processes, biomedicine, pharmacy and biotechnology. Methods such as surface and interfacial tension measurements and interfacial dilation and shear rheology characterise the relationships between these interfacial properties and the complex behaviour of foams and emulsions is established. Recently-developed experimental techniques, such as FRAP which enable the measurement of molecular mobility in adsorption layers, are covered in this volume. The development of theories to describe the thermodynamic surface state or the exchange of matter for proteins and protein/surfactant mixtures is also described.Features of this book:• Reflects the state-of-the-art research and application of protein interfacial layers rather than a snapshot of only some recent developments.• Emphasis is placed on experimental details as well as recent theoretical developments.• New experimental techniques applied to protein interfacial layers are described, such as FRAP or ADSA, or rheological methods to determine the mechanical behaviour of protein-modified interfaces.• A large number of practical applications, ranging from emulsions relevant in food technology for medical problems such as lung surfactants, to the characterisation of foams intrinsic to beer and champagne production.The book will be of interest to research and university institutes dedicated to interfacial studies in chemistry, biology, pharmacy, medicine and food engineering. Industrial departments for research and technology in food industry, pharmacy, medicine and brewery research will also find this volume of value.
Protein Instability At Interfaces During Drug Product Development
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Author : Jinjiang Li
language : en
Publisher: Springer Nature
Release Date : 2021-02-12
Protein Instability At Interfaces During Drug Product Development written by Jinjiang Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-12 with Medical categories.
Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.
Biomolecular Interfaces
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Author : Ariel Fernández Stigliano
language : en
Publisher: Springer
Release Date : 2015-04-20
Biomolecular Interfaces written by Ariel Fernández Stigliano and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-20 with Science categories.
The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.
Proteins At Solid Liquid Interfaces
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Author : Philippe Déjardin
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-09-28
Proteins At Solid Liquid Interfaces written by Philippe Déjardin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-28 with Science categories.
This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight - secondary ion mass spectrometry (TOF–SIMS). A model study of fibronectin at polymer surfaces is included, as are studies using microporous membranes and textiles with immobilized enzymes for large-scale applications. Biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules are among the other topics addressed in this invaluable book.
Food Proteins And Their Applications
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Author : Srinivasan Damodaran
language : en
Publisher: CRC Press
Release Date : 2017-10-19
Food Proteins And Their Applications written by Srinivasan Damodaran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-19 with Technology & Engineering categories.
Reviews the physiochemical properties of the main food proteins and explores the interdependency between the structure-function relationship of specific protein classes and the processing technologies applied to given foods. The book offers solutions to current problems related to the complexity of food composition, preparation and storage, and includes such topics as foams, emulsions, gelation by macromolecules, hydrolysis, microparticles/fat replacers, protein-based edible films, and extraction procedures.
Biopolymers At Interfaces Second Edition
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Author : Martin Malmsten
language : en
Publisher: CRC Press
Release Date : 2003-01-15
Biopolymers At Interfaces Second Edition written by Martin Malmsten and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-15 with Science categories.
This new edition features research from nearly 60 of the profession's most distinguished international authorities. Recognizing emerging developments in biopolymer systems research with fully updated and expanded chapters, the second edition discusses the biopolymer-based multilayer structures and their application in biosensors, the progress made in the understanding of protein behaviour at the air-water interface, experimental findings in ellipsometry and reflectometry, and recent developments concerning protein interfacial behaviour in microfabricated total analysis systems and microarrays. With over 3000 references, this is an essential reference for professionals and students in surface, pharmaceutical, colloid, polymer, and medicinal chemistry; chemical, formulation, and application engineering; and pharmacy.
Adsorption From Solution At The Solid Liquid Interface
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Author : G. D. Parfitt
language : en
Publisher:
Release Date : 1983
Adsorption From Solution At The Solid Liquid Interface written by G. D. Parfitt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
Non-electrolytes. Adsorption of small molecules. Adsorption from mixtures of miscible liquids. Adsorption of nonionic surfactants. Adsorption of polymers. Electrolytes. Adsorption of small ions. Adsorption of ionic surfactants. Adsorption of dyes. Adsorption of polyelectrolytes from dilute solution.
Surfaces And Interfaces For Biomaterials
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Author : Pankaj Vadgama
language : en
Publisher: Elsevier
Release Date : 2005-05-27
Surfaces And Interfaces For Biomaterials written by Pankaj Vadgama and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-27 with Technology & Engineering categories.
Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and interfaces for biomaterials summarises the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue.The first part of the book reviews the way biomaterial surfaces form. Part Two discusses ways of monitoring and characterising surface structure and behaviour. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility.Surfaces and interfaces for biomaterials is a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine. - Complete coverage on the fundamentals of surface structure and forming to biological and clinical outcomes - Includes reviews of key surface analytical techniques - Edited by a renowned expert and written by an international team of authors
Polyurethanes In Biomedical Applications
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Author : NinaM.K. Lamba
language : en
Publisher: Routledge
Release Date : 2017-10-19
Polyurethanes In Biomedical Applications written by NinaM.K. Lamba and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-19 with Medical categories.
Polyurethanes in Biomedical Applications studies the use of polyurethanes in implanted medical devices. This analysis describes the concepts of polymer science, the manufacture of polyurethanes, and the biological responses to implant polyurethanes, reflecting the developments in biomaterials science and the interdisciplinary nature of bioengineering.