Pseudomonas And Acinetobacter From Drug Resistance To Pathogenesis
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Pseudomonas And Acinetobacter From Drug Resistance To Pathogenesis
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Author : Ghassan M. Matar
language : en
Publisher: Frontiers Media SA
Release Date : 2018-05-03
Pseudomonas And Acinetobacter From Drug Resistance To Pathogenesis written by Ghassan M. Matar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-03 with categories.
Pseudomonas aeruginosa and Acinetobacter baumannii are among the most common non-lactose-fermenting Gram-negative pathogens responsible for hospital-acquired infections, especially in intensive care units (ICUs). The treatment of infections caused by these bacteria is complicated due to the emergence of multi-drug resistance as the two species are noted for their intrinsic resistance to antimicrobial agents and their ability to acquire genetic elements that encode for resistance determinants. In both species, resistance to multiple classes of antimicrobial agents can seriously compromise the ability to treat infected patients, especially the immunocompromised. Consequently, very few antimicrobials remain as treatment options. Mechanisms of resistance in both of these pathogens include the production of β-lactamases and aminoglycoside-modifying enzymes as well as reduced or lack of expression of outer membrane proteins, mutations in topoisomerases, and up-regulation of efflux pumps. To that purpose, the findings of the studies included in this book deal with the prevalence of resistant isolates to various antimicrobial agents in both P. aeruginosa and A. baumannii, their underlying mechanisms of resistance, their virulence factors, their pathogenesis, and prospective treatment options. Special thanks are due to Mr. Bassam El-Hafi for facilitating procedures involved in this publication.
Genetics Of Acquired Antimicrobial Resistance In Animal And Zoonotic Pathogens
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Author : Axel Cloeckaert
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-26
Genetics Of Acquired Antimicrobial Resistance In Animal And Zoonotic Pathogens written by Axel Cloeckaert and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-26 with categories.
Development and spread of antimicrobial resistance is the result of an evolutionary process by which microorganisms adapt to antibiotics through several mechanisms including alteration of drug target by mutation and horizontal transfer of resistance genes. The concomitant occurrence of independent antimicrobial resistance mechanisms is a serious threat to human health and has appeared in several emerging epidemic clones over the past decade in humans and also in animals. The increasing prevalence of antimicrobial drug resistance among animal and zoonotic foodborne pathogens is of particular concern for public health. In this Ebook, we gathered a collection of articles which deal with the most important aspects of the genetics of acquired antimicrobial resistance extending from medically-important resistance, emerging epidemic resistant clones, main mobile genetic elements spreading resistance, resistomes, dissemination between animals and humans, to the “One Health” concept.
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery
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Author : Busi Siddhardha
language : en
Publisher: Springer Nature
Release Date : 2020-03-28
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery written by Busi Siddhardha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-28 with Science categories.
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
Genomic Basis Of Antibiotic Resistance And Virulence In Acinetobacter
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Author : Santiago Castillo Ramírez
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-31
Genomic Basis Of Antibiotic Resistance And Virulence In Acinetobacter written by Santiago Castillo Ramírez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-31 with Science categories.
Microbial Pathogenesis
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Author : Uday Kishore
language : en
Publisher: Springer Nature
Release Date : 2021-10-18
Microbial Pathogenesis written by Uday Kishore and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-18 with Medical categories.
This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.
Bacterial Pathogenesis And Antibacterial Control
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Author : Sahra Kırmusaoğlu
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-30
Bacterial Pathogenesis And Antibacterial Control written by Sahra Kırmusaoğlu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Science categories.
Bacterial pathogens have been becoming the main problem in hospital and community-acquired infections. It is hard to treat the strains that are resistant to antibiotics, due to the causing recurrent and untreatable infections. In recent years, the combination treatments and the novel technologies have been preferred to overcome the emergence of antibacterial resistance of pathogens. In this book, examples of pathogenesis by clinical cases, control by antibiotics and bioactive antimicrobials, control by novel technologies with the collection of up-to-date researches and reviews are presented. This book can be useful for researchers interested in antibacterials, bioactive compounds, and novel technologies.
Acinetobacter
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Author : E. Bergogne-Berezin
language : en
Publisher: CRC Press
Release Date : 1995-12-05
Acinetobacter written by E. Bergogne-Berezin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-05 with Science categories.
Acinetobacter details the clinical aspects of this bacterium responsible for many infections in hospitalized patients. This reference explains the importance of these organisms, both from the patient's viewpoint and the economic perspective, and provides clinicians with the knowledge they need to control these bacteria.
Bacterial Pathogenesis
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Author : Brenda A. Wilson
language : en
Publisher: John Wiley & Sons
Release Date : 2020-08-11
Bacterial Pathogenesis written by Brenda A. Wilson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.
This highly anticipated update of the acclaimed textbook draws on the latest research to give students the knowledge and tools to explore the mechanisms by which bacterial pathogens cause infections in humans and animals. Written in an approachable and engaging style, the book uses illustrative examples and thought-provoking exercises to inspire students with the potential excitement and fun of scientific discovery. Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments. A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens.
Mandell Douglas And Bennett S Principles And Practice Of Infectious Diseases
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Author : John E. Bennett, MD, MACP
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-08-28
Mandell Douglas And Bennett S Principles And Practice Of Infectious Diseases written by John E. Bennett, MD, MACP and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-28 with Medical categories.
After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
Metabolic Regulation Of Drug Resistance And Pathogenicity In Aquatic Pathogens
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Author : Bo Peng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-07
Metabolic Regulation Of Drug Resistance And Pathogenicity In Aquatic Pathogens written by Bo Peng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-07 with Science categories.