Quantifying And Controlling The Nano Architecture Of Neuronal Synapses
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Quantifying And Controlling The Nano Architecture Of Neuronal Synapses
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Author : Xiaobing Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-27
Quantifying And Controlling The Nano Architecture Of Neuronal Synapses written by Xiaobing Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-27 with Science categories.
Imaging Synapse Structure And Function
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Author : George J. Augustine
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-06
Imaging Synapse Structure And Function written by George J. Augustine and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with categories.
Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.
The Hippocampus Book
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Author : Per Andersen
language : en
Publisher: Oxford University Press
Release Date : 2007
The Hippocampus Book written by Per Andersen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Encyclopedia Of Environmetrics
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Author : Abdel H. El-Shaarawi
language : en
Publisher: John Wiley & Sons
Release Date : 2002
Encyclopedia Of Environmetrics written by Abdel H. El-Shaarawi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Mathematics categories.
A comprehensive overview of environmetric research and its applications... Environmetrics covers the development and application of quantitative methods in the environmental sciences. It provides essential tools for understanding, predicting, and controlling the impacts of agents, both man-made and natural, which affect the environment. Basic and applied research in this area covers a broad range of topics. Primary among these are the quantitative sciences, such as statistics, probability and applied mathematics, chemometrics, and econometrics. Applications are also important, for example in, ecology and environmental biology, public health, atmospheric science, geology, engineering, risk management, and regulatory/governmental policy amongst others. * Divided into 12 sections, the Encyclopedia brings together over 600 detailed articles which have been carefully selected and reviewed through the collaborative efforts of the Editors-in-Chief and the appropriate Section Editor * Presented in alphabetical order all the articles will include an explanatory introduction, extensive cross-referencing and an up-to-date bibliography providing literature references for further reading. Presenting state of the art information in a readable, highly accessible style, the scope and coverage provided by the Encyclopedia of Environmetrics will ensure its place as the landmark reference for the many scientists, educators, and decision-makers working across this multidisciplinary field. An essential reference tool for university libraries, research laboratories, government institutions and consultancies concerned with the environmental sciences, the Encyclopedia of Environmetrics brings together for the first time, comprehensive coverage of the full range of topics, techniques and applications covered by this multidisciplinary field. There is currently no central reference source which addresses the needs of this multidisciplinary community. This new Encyclopedia will fill this gap by providing a comprehensive source of relevant fundamental concepts in environmetric research, development and applications for statisticians, mathematicians, economists, environmentalists, ecologist, government officials and policy makers.
Drebrin
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Author : Tomoaki Shirao
language : en
Publisher: Springer
Release Date : 2017-08-31
Drebrin written by Tomoaki Shirao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-31 with Medical categories.
This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Efficient Processing Of Deep Neural Networks
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Author : Vivienne Sze
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2020-06-24
Efficient Processing Of Deep Neural Networks written by Vivienne Sze and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-24 with Computers categories.
This book provides a structured treatment of the key principles and techniques for enabling efficient processing of deep neural networks (DNNs). DNNs are currently widely used for many artificial intelligence (AI) applications, including computer vision, speech recognition, and robotics. While DNNs deliver state-of-the-art accuracy on many AI tasks, it comes at the cost of high computational complexity. Therefore, techniques that enable efficient processing of deep neural networks to improve metrics—such as energy-efficiency, throughput, and latency—without sacrificing accuracy or increasing hardware costs are critical to enabling the wide deployment of DNNs in AI systems. The book includes background on DNN processing; a description and taxonomy of hardware architectural approaches for designing DNN accelerators; key metrics for evaluating and comparing different designs; features of the DNN processing that are amenable to hardware/algorithm co-design to improve energy efficiency and throughput; and opportunities for applying new technologies. Readers will find a structured introduction to the field as well as a formalization and organization of key concepts from contemporary works that provides insights that may spark new ideas.
Guide To Research Techniques In Neuroscience
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Author : Matt Carter
language : en
Publisher: Academic Press
Release Date : 2022-03-26
Guide To Research Techniques In Neuroscience written by Matt Carter and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-26 with Medical categories.
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Quantum Computing For The Brain
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Author : Melanie Swan
language : en
Publisher: Wspc (Europe)
Release Date : 2022
Quantum Computing For The Brain written by Melanie Swan and has been published by Wspc (Europe) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Computers categories.
Quantum Computing for the Brain argues that the brain is the killer application for quantum computing. No other system is as complex, as multidimensional in time and space, as dynamic, as less well-understood, as of peak interest, and as in need of three-dimensional modeling as it functions in real-life, as the brain. Quantum computing has emerged as a platform suited to contemporary data processing needs, surpassing classical computing and supercomputing. This book shows how quantum computing's increased capacity to model classical data with quantum states and the ability to run more complex permutations of problems can be employed in neuroscience applications such as neural signaling and synaptic integration. State-of-the-art methods are discussed such as quantum machine learning, tensor networks, Born machines, quantum kernel learning, wavelet transforms, Rydberg atom arrays, ion traps, boson sampling, graph-theoretic models, quantum optical machine learning, neuromorphic architectures, spiking neural networks, quantum teleportation, and quantum walks. Quantum Computing for the Brain is a comprehensive one-stop resource for an improved understanding of the converging research frontiers of foundational physics, information theory, and neuroscience in the context of quantum computing.
Biophysics Of Computation
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Author : Christof Koch
language : en
Publisher: Oxford University Press
Release Date : 2004-10-28
Biophysics Of Computation written by Christof Koch and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-28 with Medical categories.
Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.