Quantifying And Controlling The Nano Architecture Of Neuronal Synapses
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Quantifying And Controlling The Nano Architecture Of Neuronal Synapses
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Author : Xiaobing Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-27
Quantifying And Controlling The Nano Architecture Of Neuronal Synapses written by Xiaobing Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-27 with Science categories.
Recent Advances In Measuring And Controlling Synaptic Communication
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Author : Jacopo Lamanna
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-10
Recent Advances In Measuring And Controlling Synaptic Communication written by Jacopo Lamanna and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-10 with Science categories.
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
Molecular Nanomachines Of The Presynaptic Terminal
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Author : Silvio O. Rizzoli
language : en
Publisher: Frontiers Media SA
Release Date : 2016-10-18
Molecular Nanomachines Of The Presynaptic Terminal written by Silvio O. Rizzoli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-18 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Synaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in the formation or dissolution of memories, and can equally lead to neurological and psychiatric disorders. The proteins composing the synapse, and their respective functions, are getting increasingly known. One aspect that has become evident in the last years is that most synaptic functions are performed not by single proteins, but by highly organized multi-protein machineries, which interact dynamically to provide responses optimally suited to the needs of the neuronal network. To decipher synaptic and neuronal function, it is essential to understand the organisational, morphological and functional aspects of the molecular nanomachines that operate at the synapse. We discuss these aspects in 11 different chapters, focusing on the structure and function of the active zone, on the functional anatomy of the synaptic vesicle, and on some of the best known soluble protein complexes from the synapse, including those involved in endocytosis and vesicle recycling.
Imaging Synapse Structure And Function
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Author : George J. Augustine
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-06
Imaging Synapse Structure And Function written by George J. Augustine and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Electronic book categories.
Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.
Neuromorphic Photonics
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Author : Paul R. Prucnal
language : en
Publisher: CRC Press
Release Date : 2017-05-08
Neuromorphic Photonics written by Paul R. Prucnal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-08 with Science categories.
This book sets out to build bridges between the domains of photonic device physics and neural networks, providing a comprehensive overview of the emerging field of "neuromorphic photonics." It includes a thorough discussion of evolution of neuromorphic photonics from the advent of fiber-optic neurons to today’s state-of-the-art integrated laser neurons, which are a current focus of international research. Neuromorphic Photonics explores candidate interconnection architectures and devices for integrated neuromorphic networks, along with key functionality such as learning. It is written at a level accessible to graduate students, while also intending to serve as a comprehensive reference for experts in the field.
Shedding Light On The Nervous System Progress In Neurophotonics Research
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Author : Jean-Claude Béïque
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-01
Shedding Light On The Nervous System Progress In Neurophotonics Research written by Jean-Claude Béïque and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-01 with Science categories.
Scientific And Technical Aerospace Reports
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Author :
language : en
Publisher:
Release Date : 1992
Scientific And Technical Aerospace Reports written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Aeronautics categories.
Methods For Synaptic Interrogation
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Author : Dirk Feldmeyer
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14
Methods For Synaptic Interrogation written by Dirk Feldmeyer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
From Cell Physiology To Emerging Brain Functions
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Author : Philippe Isope
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-11
From Cell Physiology To Emerging Brain Functions written by Philippe Isope and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-11 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Current Opinion In Biotechnology
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Author :
language : en
Publisher:
Release Date : 1995
Current Opinion In Biotechnology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Biotechnology categories.