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Quantile Regression In Clinical Research


Quantile Regression In Clinical Research
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Quantile Regression In Clinical Research


Quantile Regression In Clinical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer Nature
Release Date : 2022-01-17

Quantile Regression In Clinical Research written by Ton J. Cleophas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-17 with Medical categories.


Quantile regression is an approach to data at a loss of homogeneity, for example (1) data with outliers, (2) skewed data like corona - deaths data, (3) data with inconstant variability, (4) big data. In clinical research many examples can be given like circadian phenomena, and diseases where spreading may be dependent on subsets with frailty, low weight, low hygiene, and many forms of lack of healthiness. Stratified analyses is the laborious and rather explorative way of analysis, but quantile analysis is a more fruitful, faster and completer alternative for the purpose. Considering all of this, we are on the verge of a revolution in data analysis. The current edition is the first textbook and tutorial of quantile regressions for medical and healthcare students as well as recollection/update bench, and help desk for professionals. Each chapter can be studied as a standalone and covers one of the many fields in the fast growing world of quantile regressions. Step by step analyses of over 20 data files stored at extras.springer.com are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology(2000-2002). From their expertise they should be able to make adequate selections of modern quantile regression methods for the benefit of physicians, students, and investigators.



Quantile Regression In Clinical Research


Quantile Regression In Clinical Research
DOWNLOAD
Author : Ton J. Cleophas
language : en
Publisher:
Release Date : 2021

Quantile Regression In Clinical Research written by Ton J. Cleophas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


Quantile regression is an approach to data at a loss of homogeneity, for example (1) data with outliers, (2) skewed data like corona - deaths data, (3) data with inconstant variability, (4) big data. In clinical research many examples can be given like circadian phenomena, and diseases where spreading may be dependent on subsets with frailty, low weight, low hygiene, and many forms of lack of healthiness. Stratified analyses is the laborious and rather explorative way of analysis, but quantile analysis is a more fruitful, faster and completer alternative for the purpose. Considering all of this, we are on the verge of a revolution in data analysis. The current edition is the first textbook and tutorial of quantile regressions for medical and healthcare students as well as recollection/update bench, and help desk for professionals. Each chapter can be studied as a standalone and covers one of the many fields in the fast growing world of quantile regressions. Step by step analyses of over 20 data files stored at extras.springer.com are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology(2000-2002). From their expertise they should be able to make adequate selections of modern quantile regression methods for the benefit of physicians, students, and investigators. .



Regression Analysis In Medical Research


Regression Analysis In Medical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer Nature
Release Date : 2021-03-01

Regression Analysis In Medical Research written by Ton J. Cleophas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-01 with Science categories.


Regression analysis of cause effect relationships is increasingly the core of medical and health research. This work is a 2nd edition of a 2017 pretty complete textbook and tutorial for students as well as recollection / update bench and help desk for professionals. It came to the authors' attention, that information of history, background, and purposes, of the regression methods addressed were scanty. Lacking information about all of that has now been entirely covered. The editorial art work of the first edition, however pretty, was less appreciated by some readerships, than were the original output sheets from the statistical programs as used. Therefore, the editorial art work has now been systematically replaced with original statistical software tables and graphs for the benefit of an improved usage and understanding of the methods. In the past few years, professionals have been flooded with big data. The Covid-19 pandemic gave cause for statistical software companies to foster novel analytic programs better accounting outliers and skewness. Novel fields of regression analysis adequate for such data, like sparse canonical regressions and quantile regressions, have been included.



Modern Survival Analysis In Clinical Research


Modern Survival Analysis In Clinical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer Nature
Release Date : 2023-05-29

Modern Survival Analysis In Clinical Research written by Ton J. Cleophas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-29 with Medical categories.


An important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.



Regression Analysis In Medical Research


Regression Analysis In Medical Research
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Author : Ton J. Cleophas
language : en
Publisher:
Release Date : 2021

Regression Analysis In Medical Research written by Ton J. Cleophas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


Regression analysis of cause effect relationships is increasingly the core of medical and health research. This work is a 2nd edition of a 2017 pretty complete textbook and tutorial for students as well as recollection / update bench and help desk for professionals. It came to the authors' attention, that information of history, background, and purposes, of the regression methods addressed were scanty. Lacking information about all of that has now been entirely covered. The editorial art work of the first edition, however pretty, was less appreciated by some readerships, than were the original output sheets from the statistical programs as used. Therefore, the editorial art work has now been systematically replaced with original statistical software tables and graphs for the benefit of an improved usage and understanding of the methods. In the past few years, professionals have been flooded with big data. The Covid-19 pandemic gave cause for statistical software companies to foster novel analytic programs better accounting outliers and skewness. Novel fields of regression analysis adequate for such data, like sparse canonical regressions and quantile regressions, have been included. .



Focused Model Selection In Quantile Regression


Focused Model Selection In Quantile Regression
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Author : Peter Behl
language : en
Publisher:
Release Date : 2012

Focused Model Selection In Quantile Regression written by Peter Behl and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.




Quantile Regression


Quantile Regression
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Author : Lingxin Hao
language : en
Publisher: SAGE Publications
Release Date : 2007-04-18

Quantile Regression written by Lingxin Hao and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-18 with Social Science categories.


Quantile Regression, the first book of Hao and Naiman′s two-book series, establishes the seldom recognized link between inequality studies and quantile regression models. Though separate methodological literature exists for each subject, the authors seek to explore the natural connections between this increasingly sought-after tool and research topics in the social sciences. Quantile regression as a method does not rely on assumptions as restrictive as those for the classical linear regression; though more traditional models such as least squares linear regression are more widely utilized, Hao and Naiman show, in their application of quantile regression to empirical research, how this model yields a more complete understanding of inequality. Inequality is a perennial concern in the social sciences, and recently there has been much research in health inequality as well. Major software packages have also gradually implemented quantile regression. Quantile Regression will be of interest not only to the traditional social science market but other markets such as the health and public health related disciplines. Key Features: Establishes a natural link between quantile regression and inequality studies in the social sciences Contains clearly defined terms, simplified empirical equations, illustrative graphs, empirical tables and graphs from examples Includes computational codes using statistical software popular among social scientists Oriented to empirical research



Kernel Ridge Regression In Clinical Research


Kernel Ridge Regression In Clinical Research
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Author : Ton J. Cleophas
language : en
Publisher: Springer Nature
Release Date : 2022-09-12

Kernel Ridge Regression In Clinical Research written by Ton J. Cleophas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-12 with Science categories.


IBM (international business machines) has published in its SPSS statistical software 2022 update a very important novel regression method entitled Kernel Ridge Regression (KRR). It is an extension of the currently available regression methods, and is suitable for pattern recognition in high dimensional data, particularly, when alternative methods fail. Its theoretical advantages are plenty and include the kernel trick for reduced arithmetic complexity, estimation of uncertainty by Gaussians unlike histograms, corrected data-overfit by ridge regularization, availability of 8 alternative kernel density models for datafit. A very exciting and wide array of preliminary KRR research has already been published by major disciplines (like studies in quantum mechanics and nuclear physics, studies of molecular affinity / dynamics, atomisation energy studies, but also forecasting economics studies, IoT (internet of things) studies for e-networks, plant stress response studies, big data streaming studies, etc). In contrast, it is virtually unused in clinical research. This edition is the first textbook and tutorial of kernel ridge regressions for medical and healthcare students as well as recollection / update bench, and help desk for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional regression analyses. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern KRR methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 24 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.



On Testing The Change Point In The Longitudinal Bent Line Quantile Regression Model


On Testing The Change Point In The Longitudinal Bent Line Quantile Regression Model
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Author : Nanshi Sha
language : en
Publisher:
Release Date : 2011

On Testing The Change Point In The Longitudinal Bent Line Quantile Regression Model written by Nanshi Sha and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.


Furthermore, we demonstrate, through a series of simulations, that the proposed methods also outperform the extensively used bootstrap methods by providing more accurate and computationally efficient confidence intervals. To illustrate the usage of our methods, we apply them to two datasets from real studies: the Finnish Longitudinal Growth Study and an AIDS clinical trial. In each case, the proposed approach sheds light on the response pattern by providing an estimated location of abrupt change along with its 95% confidence interval at any quantile of interest -- a key parameter with clinical implications. The proposed methods allow for different change-points at different quantile levels of the outcome. In this way, they offer a more comprehensive picture of the covariate effects on the response variable than is provided by other change-point models targeted exclusively on the conditional mean. We conclude that our framework and proposed methodology are valuable for studying the change-point problem involving longitudinal data.



Application Of Statistical Tools In Biomedical Domain An Overview With Help Of Software


Application Of Statistical Tools In Biomedical Domain An Overview With Help Of Software
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Author : Editor, ISJMI
language : en
Publisher: Create Space
Release Date : 2018-03-30

Application Of Statistical Tools In Biomedical Domain An Overview With Help Of Software written by Editor, ISJMI and has been published by Create Space this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-30 with Medical categories.


This book is an edited book from the papers of International Journal of Statistics and Medical Informatics authored by Editor, International of Statistics and Medical Informatics. It covers topics such as systematic review and meta-analysis, factor analysis, structural equation modelling and quantile regression in the field of biomedical domain. It also provides insight into the post hoc comparison, clinical trail data management and natural language processing