Quorum Network Sensing Quenching In Multidrug Resistant Pathogens
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Quorum Network Sensing Quenching In Multidrug Resistant Pathogens
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Author : Rodolfo Garcia-Conteras
language : en
Publisher: Frontiers Media SA
Release Date : 2019-06-28
Quorum Network Sensing Quenching In Multidrug Resistant Pathogens written by Rodolfo Garcia-Conteras and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-28 with categories.
The findings of the contributed studies from this Research Topic reflect important aspects (hot topics) of Quorum network (Sensing/Quenching) in multidrug-resistant pathogens, which including: (i) novel mechanisms of QS and detection techniques, (ii) QS/QQ in clinical multidrug resistant strains, (iii) the relationship between QS/QQ as well as multidrug resistance, and (iv) the application of new QQ therapies.
Trends In Quorum Sensing And Quorum Quenching
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Author : V. Ravishankar Rai
language : en
Publisher: CRC Press
Release Date : 2020-05-04
Trends In Quorum Sensing And Quorum Quenching written by V. Ravishankar Rai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-04 with Science categories.
The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling
Beyond Antimicrobials Non Traditional Approaches To Combating Multidrug Resistant Bacteria
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Author : Natalia V. Kirienko
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-24
Beyond Antimicrobials Non Traditional Approaches To Combating Multidrug Resistant Bacteria written by Natalia V. Kirienko and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-24 with categories.
Quorum Quenching
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Author : Naga Raju Maddela
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-12-15
Quorum Quenching written by Naga Raju Maddela and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-15 with Science categories.
Antibiotic resistance is a global health concern. Strains of pathogenic microorganisms that have developed resistance to multiple antibiotics, such as MRSA, are extremely difficult to treat, and alternative methods for tackling pathogenic microorganisms are in demand. One potential target for new therapeutics is inhibition of quorum sensing: how microorganisms communicate and form biofilms in a density-dependent manner. Inhibiting this system via ‘quorum quenching’ (QQ) is a promising route to new pharmaceuticals and for controlling biofilm formation and growth. Quorum sensing also provides interesting possibilities in synthetic biology for producing novel products, biosensors, bioactive molecules, and so on. This book covers the biology of quorum sensing and quenching, and potential sources of QQ enzymes and other inhibitors, as well as an overview of their mechanism and potential biotech applications. The book also covers the potential for new drug development from QQ, covering a range of related topics including protein engineering, imaging and computational studies, and integrated systems. This book is an ideal companion to researchers in chemical biology and medicinal chemistry, particularly those interested in biofilm formation, quorum sensing, novel antimicrobial development, synthetic biology and enzymology.
Biotechnological Applications Of Quorum Sensing Inhibitors
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2018-05-30
Biotechnological Applications Of Quorum Sensing Inhibitors written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Science categories.
This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors. Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.
Alternatives To Combat Bacterial Infections
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Author : Rodolfo García-Contreras
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-26
Alternatives To Combat Bacterial Infections written by Rodolfo García-Contreras and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-26 with Science categories.
Quorum Sensing Vs Quorum Quenching A Battle With No End In Sight
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2014-09-29
Quorum Sensing Vs Quorum Quenching A Battle With No End In Sight written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-29 with Science categories.
Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?
Facing The Upcoming Of Multidrug Resistant And Extensively Drug Resistant Bacteria Novel Antimicrobial Therapies Nats
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Author : Angel León-Buitimea
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-01
Facing The Upcoming Of Multidrug Resistant And Extensively Drug Resistant Bacteria Novel Antimicrobial Therapies Nats written by Angel León-Buitimea and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Science categories.
Contemporary Approaches To Mitigating Antibacterial Drug Resistance
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Author : Grewal, Ajmer Singh
language : en
Publisher: IGI Global
Release Date : 2024-04-01
Contemporary Approaches To Mitigating Antibacterial Drug Resistance written by Grewal, Ajmer Singh and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-01 with Medical categories.
In infectious disease management, antibacterial agents have long been viewed as pivotal tools in the relentless battle against microorganisms. However, the escalating threat of antibacterial drug resistance has emerged as a formidable challenge to global health. Contemporary Approaches to Mitigating Antibacterial Drug Resistance delves into the heart of this critical issue, exploring the mechanisms, consequences, and innovative strategies to counteract the surge of resistance, a phenomenon becoming increasingly pervasive and threatening worldwide. Antibacterial drug resistance, a pressing public health concern, transcends geographical boundaries. In regions where antibiotic accessibility and overuse prevail, resistance rates soar, giving rise to the ominous "superbugs." This book unravels the intricacies of drug resistance, examining its impact on infectious disease management, healthcare economics, and societal well-being. The exploration begins with a foundational understanding of antibacterial drug resistance, navigating through the intricate mechanisms that drive its rapid proliferation. Environmental and genetic factors, often overlooked, are dissected for their roles in fostering resistance. The book explores the interplay of antibacterial drugs with micro-biodiversity, shedding light on the indirect repercussions on human and environmental ecosystems. The primary audience, encompassing undergraduate and postgraduate students, medical practitioners, academicians, and researchers, will find in-depth insights into emerging therapeutic targets and recent advances in drug development. The secondary audience, including authorities in antibacterial drug resistance and institutional libraries, will discover a valuable resource addressing the multifaceted dimensions of this global menace.
Quorum Sensing And Its Biotechnological Applications
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2018-08-11
Quorum Sensing And Its Biotechnological Applications written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-11 with Medical categories.
This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy, Agriculture and Health sectors.