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Recent Advances In Noncoding Rnas


Recent Advances In Noncoding Rnas
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Recent Advances In Noncoding Rnas


Recent Advances In Noncoding Rnas
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Author : Lütfi Tutar
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-11-02

Recent Advances In Noncoding Rnas written by Lütfi Tutar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-02 with Medical categories.


The discovery of noncoding RNAs (ncRNAs) is changed our understanding of genome, transcriptome, and interactions with proteome in a cell. Since the discovery of the first microRNA (miRNA) called lin-4 on Caenorhabditis elegans in 1993, our understanding of gene expression has deepened. Further miRNA discoveries have led to the investigation of new ncRNA families and their function, biogenesis, and interactions with other types of molecules. Recent developments in bioinformatics, public databases, sequencing technologies, and biochemical techniques have increased our understanding of the biogenesis, function, and interactions of ncRNAs. This book provides an overview of current ncRNA research dealing with human diseases and cancer and plant miRNAs.



Long Noncoding Rnas In Plants


Long Noncoding Rnas In Plants
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Author : Santosh Kumar Upadhyay
language : en
Publisher: Academic Press
Release Date : 2020-11-13

Long Noncoding Rnas In Plants written by Santosh Kumar Upadhyay and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Science categories.


The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. - Includes the latest advances and research in long noncoding RNAs in plants - Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops - Focuses on the application and uses of long noncoding RNAs



Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges


Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges
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Author : Carlo Maria Croce
language : en
Publisher: Frontiers Media SA
Release Date : 2017-01-27

Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges written by Carlo Maria Croce and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.


The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginning to be uncovered. Genetic and epigenetic aberrations affecting ncRNA gene sequences and their expression have been linked to a variety of pathological conditions, including cancer, cardiovascular and neurological diseases. Latest advances in the development of high throughput analysis techniques may help to shed light on the complex regulatory mechanisms in which ncRNA molecules are involved. Bioinformatics tools constitute a unique and essential resource for non-coding RNA studies, providing a powerful technology to organize, integrate and analyze the huge amount of data produced daily by wet biology experiments in order to discover patterns, identify relationships among heterogeneous biological elements and formulate functional hypotheses. This Research Topic reviews current knowledge, introduces novel methods, and discusses open challenges of this exciting and innovative field in connection with the most important biomedical applications. It consists of four reviews and six original research and methods articles, spanning the full scope of the Research Topic.



Recent Advances In Ipsc Technology


Recent Advances In Ipsc Technology
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Author : Alexander Birbrair
language : en
Publisher: Academic Press
Release Date : 2021-03-31

Recent Advances In Ipsc Technology written by Alexander Birbrair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Science categories.


The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies.Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use iPSCs for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-the-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. This volume will cover hot topics in the iPSC field, such as iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the noncoding genome, modeling of blood–brain barrier with iPSCs, mathematical modeling of iPSCs, iPSCs to study human brain evolution, selfrenewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more.The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics - Covers the following topics: iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the non-coding genome, modeling of blood-brain barrier with iPSCs, mathematical modelling of iPSCs, iPSCs to study human brain evolution, self-renewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more - Contributed by world-renown experts in the field



Recent Advances In Endometriosis From Bench To Clinical Application


Recent Advances In Endometriosis From Bench To Clinical Application
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Author : Achmad Kemal Harzif
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-27

Recent Advances In Endometriosis From Bench To Clinical Application written by Achmad Kemal Harzif and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-27 with Medical categories.


Endometriosis is a benign and enigmatic disease estimated to affect 6–10% of women of reproductive age. It has been associated with two significant problems, chronic pelvic pain and subfertility. Endometriosis is an estrogen-dependent disorder described as the presence of endometrial glands and stroma outside the uterine cavity. This disease may have undesirable consequences on a woman's physical and emotional well-being. Accordingly, it may attenuate women's quality of life and productivity. Likewise, Endometriosis can cause substantial economic and social problems for patients, families, and society. Despite its high prevalence, cost, and many published articles, the pathogenesis of Endometriosis remains controversial due to the lack of robust evidence. This issue may consequently restrict our understanding of the disease and decelerate innovation in diagnostic and treatment options. It is now well accepted that a combination of genetic, hormonal, and immunological factors may contribute to the development of Endometriosis. Endometriosis treatments have been primarily focused on alleviating the symptoms and not the underlying mechanisms of the disease. The nature of individual influencing factors, immune system and peritoneal cavity of women with Endometriosis remains to be elucidated. Although the advances in research over the years have enhanced our understanding associated with hormones and their receptors, immune disorder, the principle of hormonal treatments for Endometriosis, comprehensive and interdisciplinary approaches to disease management, and awareness for patients and health care providers are compulsory to eradicate stigma, intensify an accurate diagnosis and permit for new developments.



New Advances In Rna Targeting


New Advances In Rna Targeting
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Author : Olga N. Ilinskaya
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04

New Advances In Rna Targeting written by Olga N. Ilinskaya and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with RNA targeting categories.




Recent Advances In The Molecular Genetics Of Glioma


Recent Advances In The Molecular Genetics Of Glioma
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Author : Pawel Buczkowicz
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-30

Recent Advances In The Molecular Genetics Of Glioma written by Pawel Buczkowicz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-30 with Science categories.


Gliomas are central nervous tumours with a glial cell of origin, such as neural stem cells, astrocytes and oligodendrocytes. They usually occur in the brain (supratentorial, infratentorial, brainstem) but occasionally originate in the spine. Gliomas may be benign or malignant, comprise of various histopathological subtypes and WHO grades (I-IV). Despite having a low incidence rate of around 3.19 per 100,000 (in the US) and a median age of 64 years for a first diagnosis, gliomas account for 80% of malignant brain tumours, and are most often fatal; they are the leading cause of cancer-related death among males from the ages of 0-39 and in females aged 0-19.



Plant Biotechnology Recent Advancements And Developments


Plant Biotechnology Recent Advancements And Developments
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Author : Suresh Kumar Gahlawat
language : en
Publisher: Springer
Release Date : 2017-05-31

Plant Biotechnology Recent Advancements And Developments written by Suresh Kumar Gahlawat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-31 with Science categories.


This book presents an overview of the latest advances and developments in plant biotechnology. The respective chapters explore emerging areas of plant biotechnology such as RNAi technology, fermentation technology, genetic engineering, nanoparticles and their applications, climate resilient crops, bio-films, bio-plastic, bio-remediation, flavonoids, antioxidants etc. All chapters were written by respected experts and address the latest developments in plant biotechnology that are of industrial importance, especially with regard to crop yields and post-harvest strategies. As such, the book offers a valuable guide for students, educators and researchers in all disciplines of the life sciences, agricultural sciences, medicine, and biotechnology at universities, research institutions and biotechnology companies.



Long Noncoding Rnas


Long Noncoding Rnas
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Author : Riki Kurokawa
language : en
Publisher: Springer
Release Date : 2015-06-30

Long Noncoding Rnas written by Riki Kurokawa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-30 with Science categories.


This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approaches lead to insights into molecular mechanisms of these lncRNA actions. At the cellular or individual level of analysis, we grasp the biology and medicine of lncRNAs. These three layers of approaches are thoroughly new and produce novel insights into functions of lncRNAs in living cells. The book consists of five parts: 1) Bioinformatics and other methodologies for lncRNAs, 2) Atomic and molecular structures of lncRNAs, 3) Molecular functions of lncRNAs, 4) Biological actions of lncRNAs, and 5) Potential outcomes for clinical medicine. These sections connect well and work synergistically. The book is for researchers whose specialty is RNA biology and chemistry and also for advanced students at the graduate and undergraduate levels. Readers can grasp the leading edge of lncRNA studies in a comprehensive manner and are inspired to pursue their own particular interests.



Recent Advances In Molecular Targets For Drug Discovery And Delivery In Tumor


Recent Advances In Molecular Targets For Drug Discovery And Delivery In Tumor
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Author : Sanjun Shi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-05

Recent Advances In Molecular Targets For Drug Discovery And Delivery In Tumor written by Sanjun Shi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Science categories.